张　智　中国科学技术大学生命科学学院教授、博士生导师，国家****基金获得者，科技部青年973首席科学家。2001年毕业于安徽大学并获生物化学学士学位，2008年获中国科学技术大学神经生物学博士学位，2008-2012年在美国德克萨斯大学MD Anderson cancer center麻醉与疼痛医学系从事博士后工作，主要研究疼痛与情绪相互作用的分子和神经环路机制，以通讯作者在Nature Neuroscience、PNAS和Anesthesiology等学术期刊上发表多篇相关论文，分别被Nature Reviews Neuroscience和Nature Reviews Drug Discovery Highlight。2012年11月起任中国科学技术大学生命科学学院教授，兼任中科院脑功能与脑疾病重点实验室副主任和安徽省神经科学学会秘书长。
主要研究兴趣:
1.疼痛与情绪疾病（抑郁和焦虑等）相互作用的神经机制
2. 中枢神经系统和外周器官相互作用机制
3.调控疼痛和情绪神经环路的物理刺激方式（声、光、电和磁刺激）
代表性论文:
Xia Zhu^#;Hao-Di Tang^#;Wan-Ying Dong^#;Fang Kang^#; An Liu; Yu Mao; Wen Xie; Xulai Zhang; Peng Cao; Wenjie Zhou; Haitao Wang; Zahra Farzinpou; Wenjuan Tao; Xiaoyuan Song; Yan Zhang; Tian Xue; Yan Jin*; Juan Li*; Zhi Zhang*; Distinct thalamocortical circuits underlie allodynia induced by tissue injury and by depression-like states, Nature Neuroscience, 2021, 24(4): 542-553.
Kai An; Huan Zhao*; Ying Miao; Qi Xu; Yu-Fei Li; Yu-Qian Ma; Yi-Ming Shi; Jia-Wei Shen; Jian-Jun Meng; Yong-Gang Yao; Zhi Zhang; Ju-Tao Chen; Jin Bao; Mei Zhang; Tian Xue*; A circadian rhythm-gated subcortical pathway for nighttime-light-induced depressive-like behaviors in mice,Nature Neuroscience, 2020, 23(7): 869-880.
Peng Chen; Shihao Lou; Zhao-Huan Huang; Zhenni Wang; Qing-Hong Shan; Yu Wang; Yupeng Yang; Xiangning Li; Hui Gong; Yan Jin;Zhi Zhang; Jiang-Ning Zhou*; Prefrontal cortex corticotropin-releasing factor neurons control behavioral style selection under challenging situations,Neuron, 2020, 106: 1-15.
Wenjuan Tao^#; Changmao Chenb^#; Yuping Wang^#; Wenjie Zhou; Yan Jin; Yu Mao; Haitao Wang; Likui Wang; Wen Xie; Xulai Zhangd; Jie Li; Juan Li; Xiangyao Lie; Zhen-Quan Tang; Chenghua Zhoug; Zhizhong Z. Pang*; Zhi Zhang*; MeCP2 mediates transgenerational transmission of chronic pain,Progress in Neurobiology, 2020, 189:101790.
Yan Jin^#; Qian Meng^#; Lisheng Mei; Wenjie Zhou; Xia Zhu; Yu Mao; Wen Xie; Xulai Zhang; Min-Hua Luo; Wenjuan Tao; Haitao Wang; Jie Li; Juan Li; Xiangyao Li;Zhi Zhang*; A somatosensory cortex input to the caudal dorsolateral striatum controls comorbid anxiety in persistent pain,PAIN, 2020, 161(2): 416-428.
Weiwei Yin^#; Lisheng Mei^#; Tingting Sun; Yuping Wang; Jie Li; Changmao Chen; Zahra Farzinpour; Yu Mao; Wenjuan Tao; Juan Li; Wen Xie; Zhi Zhang*; A central amygdala–ventrolateral periaqueductal gray matter pathway for pain in a mouse model of depression-like behavior,Anesthesiology, 2020, Jan 27.
Wenjie Zhou^#; Yan Jin^#; Qian Meng^#; Xia Zhu^#; Tongjian Bai; Yanghua Tian; Yu Mao; Likui Wang; Wen Xie; Hui Zhong; Na Zhang; Min-Hua Luo; Wenjuan Tao; Haitao Wang; Jie Li; Juan Li; Ben-Sheng Qiu; Jiang-Ning Zhou; Xiangyao Li; Han Xu; Kai Wang; Xiaochu Zhang; Yong Liu; Gal Richter-Levin; Lin Xu;Zhi Zhang*; A neural circuit for comorbid depressive symptoms in chronic pain,Nature Neuroscience, 2019, 22(10): 1649-1658.
Tingting Sun^#; Zihua Song^#; Yanghua Tian^#; Wenbo Tian; Chunyan Zhu; Gongjun Ji; Yudan Luo; Shi Chen; Likui Wang; Yu Mao; Wen Xie; Hui Zhong; Fei Zhao; Min-Hua Luo; Wenjuan Tao; Haitao Wang; Jie Li; Juan Li; Jiang-Ning Zhou; Kai Wang*;Zhi Zhang*; Basolateral amygdala input to the medial prefrontal cortex controls obsessive-compulsive disorder-like checking behavior,PNAS, 2019, 116(9): 3799-3804.
Xia Zhu^#; Wenjie Zhou^#; Yan Jin; Haodi Tang; Peng Cao; Yu Mao; Wen Xie; Xulai Zhang; Fei Zhao; Min-Hua Luo; Haitao Wang; Jie Li; Wenjuan Tao; Zahra Farzinpour; Likui Wang; Xiangyao Li; Juan Li; Zheng-Quan Tang; Chenghua Zhou; Zhizhong Z. Pan*;Zhi Zhang*; A central amygdala input to the parafascicular nucleus controls comorbid pain in depression,Cell Reports, 2019, 29(12): 3847-3858.
Haitao Wang^#; Jiahui Chen^#; Xiaotong Xu; Wen-Jian Sun; Xi Chen; Fei Zhao; Min-Hua Luo; Chunhua Liu; Yiping Guo; Wen Xie; Hui Zhong; Tongjian Bai; Yanghua Tian; Yu Mao; Chonghuan Ye; Wenjuan Tao; Jie Li; Zahra Farzinpour; Juan Li; Jiang-Ning Zhou; Kai Wang; Jufang He; Lin Chen*;Zhi Zhang*; Direct auditory cortical input to the lateral periaqueductal gray controls sound-driven defensive behavior,PLoS Biology, 2019, 17(8): e**.
Zhi Zhang; Wenjuan Tao; Yuan-Yuan Hou; Wei Wang; Paul J. Kenny; Zhizhong Z. Pan*; MeCP2 repression of G9a in regulation of pain and morphine reward,Journal of Neuroscience, 2014, 34(27): 9076-9087.
Zhi Zhang; You-Qing Cai; Fang Zou; Bihua Bie; Zhizhong Z. Pan*; Epigenetic suppression of GAD65 expression mediates persistent pain,Nature Medicine, 2011, 17(11): 1448-1455. Highlighted byNature Reviews Drug Discovery(2011 Nov 18;10(12):900).
Zhi Zhang; Zhizhong Z. Pan*; Synaptic mechanism for functional synergism between delta- and mu-opioid receptors,Journal of Neuroscience, 2010, 30(13): 4735-4745.Highlighted byNature Reviews Neuroscience(2010 May 12; 11:374-375).
Zhi Zhang; Neng Gong; Wei Wang; Lin Xu; Tian-Le Xu*; Bell-shaped D-serine actions on hippocampal long-term depression and spatial memory retrieval,Cerebaral Cortex, 2008, 18(10): 2391-2401.
招生招聘：
实验室招聘免疫学和胶质细胞等相关背景的博士后/副研究员/研究员。
联系方式：zhizhang@ustc.edu.cn
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