Name: Xuebiao Yao（X. Yao, 姚雪彪）
　Address: Laboratory of Cellular Dynamics, University of Science and Technology of China,

230026 Hefei,P. R. China
　Tel: 86-
　Fax: 86-
　E-mail: yaoxb@ustc.edu.cn

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　EDUCATION AND RESEARCH EXPERIENCE
1980-1984
B.S., Jiangxi College of Chinese Medicine, China
1991-1995
Ph.D., University of California-Berkeley, USA
1995-1997
Research Associate, University of California-San Diego, USA
1997-1999
Assistant Professor, University of Wisconsin-Madison, USA
2000-2003
Visiting Research Professor, University of California-Berkeley, USA
2003-2008
Georgia Cancer Coalition Eminent Scholar, USA
1999-
Professor of Cell Biology, University of Science & Technology of China
2008-
Director, Anhui Key Laboratory for Cellular Dynamics and Chemical Biology, China
2016-
Head, Innovation Team on Centromere Dynamics & Plasticity Control, Natural Science Foundation of China


　RESEARCH INTERESTS
1.
Chromosome segregation and stemness control
2.
Organoids architect and plasticity control
3.
Chemical biology of mitosis and metastasis
4.
Single molecule and super-resolution imaging


　CURRENT RESEARCH PROJECTS
1.
Centromere Dynamics & Plasticity Control, Natural Science Foundation of China (2017-2012)
2.
Chemical biology of mitosis, Chinese Academy of Sciences (2016-2020)
3.
Single cell dynamics, Natural Science Foundation of China (2015-2019)


　REPRESENTATIVE PUBLICATIONS
1.
Ding, X; Yan, F; Yao, P; Yang, Z; Wan, W; Wang, X; Liu, J; Gao, X; Abrieu, A; Zhu, T; Zhang, J; Dou, Z;Yao, X. 2010. Probing CENP-E function in mitotic chromosome dynamics using small molecule inhibitor syntelin.Cell Research20, 1386-1389.

2.
Chen Y, Wang D, Guo Z, Zhao J, Wu B, Deng H, Xiang H, Gao F, Yu X, Liao J, Ward T, Xia P, Emenari C. Ding X, Thompson W, Ma K, Zhu J, Aikhionbare F, Dou K, Zhu J, Cheng S, andYao X. 2011. Rho kinase phosphorylation promotes ezrin-mediated metastasis in hepatocellular carcinoma.Cancer Research71, 1721-1730.

3.
Chen J, Yu F, Gong C, Yao D, Deng H, Wang F, Anderson K, Liu Q, McEwen M,Yao X*, Song E*. 2011. CCL18 from tumor associated macrophages promotes breast cancer metastasis via PITPNM3.Cancer Cell19, 541-555; *correspondence.

4.
Tao Y, Jin C, Li X, Qi S, Chu L, Niu L,Yao X*, Teng M*. 2012. The structure of the FANCM-MHF complex reveals physical features for functional assembly.Nature Commun. 3, 782-791.

5.
Xia P, Wang Z, Liu X, Wu B, Ward T, Zhang L, Ding X, Gibbons G, Shi Y,Yao X. 2012. EB1 acetylation by PCAF ensures accurate kinetochore-microtubule interactions in mitosis.Proc Natl Acad Sci U S A. 109, 16564-9.

6.
Zhao X, Wang D, Liu X, Liu L, Song Z, Zhu T, Adams G, Gao X, Tian R, Huang Y, Chen R, Wang F, Liu D, Yu X, Chen Y, Chen Z, Teng M, Ding X,Yao X. 2013. Phosphorylation of BAR domain of ACAP4 regulates membrane tubulation.Proc Natl Acad Sci USA. 110, 11023-8.

7.
Yao X, Li D, Pei G. 2013. In focus: Molecular and Cell Biology Research in China.Nat Rev Mol Cell Biol. 14, 600-606.

8.
Dou Z, Liu X, Wang W, Zhu T, Wang X, Xu L, Abrieu A, Fu C, Hill DL,Yao X*. 2015. Dynamic localization of Mps1 kinase to kinetochores is essential for accurate spindle microtubule attachment.Proc Natl Acad Sci USA.112, E4546-55

9.
Mo F, Zhuang X, Liu X*, Yao P, Qin B, Su Z, Zang J, Wang Z, Zhang J, Niu L, Hill DL, Fang G, Fu C,Yao X*. 2016. Acetylation of Aurora B by TIP60 ensures accurate chromosomal segregation.Nature Chem. Biol. 12, 226-232. *correspondence.