姓　　名:
黄成栋
地　　址:
安徽省合肥市中国科学技术大学生命科学学院附楼706
邮　　编:
230027
电　　话:
(0551)-**
电　　邮:
huangcd@ustc.edu.cn
主　　页:
https://biox.ustc.edu.cn/2017/0301/c699a167436/page.htm

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　教育与科研经历


2001年毕业于大连理工大学获得工科学士学位；2004年于中科院大连化学物理研究所获工科硕士学位；2010年于美国奥本大学化学系获生物化学博士学位。此后先后在石溪大学、罗格斯大学以及明尼苏达大学从事博士后研究。多年来一直从事生物核磁共振领域的研究，在Nature、PNAS、JACS等国际期刊上发表了系列文章，并在Annual Review of Biophysics杂志上撰写综述文章。



　目前研究方向


应用生物核磁共振解析动态生物大分子的结构及功能机理


　代表性论文
1.
Huang, Chengdong;Kalodimos, Charalampos, G. Structures of Large Protein Complexes by NMR.Annu. Rev. Biophys.(2017) 46，317-336.
2.
Huang, Chengdong; Rossi, Paolo; Saio, Tomohide; Kalodimos, Charalampos, G. Structural basis for the antifolding activity of a molecular chaperone.Nature. (2016) 537, 202-206.
3.
Rath, Poonam;Huang, Chengdong; Wang, Tao; Wang, Tianzhi; Li, Huilin; Prados-Rosales, Rafael; Elemento, Olivier; Casadevall, Arturo; Nathan, Carl F. Genetic regulation of vesiculogenesis and immunomodulation in Mycobacterium tuberculosis.Proc. Natl. Acad. Sci. USA.(2013) 110(49), E4790-4797.
4.
Huang, Chengdong*;Li, Guangtao*; Lennarz, William J.Dynamic flexibility of the ATPase p97 is important for its interprotomer motion transmission.(*Equal contribution)Proc. Natl. Acad. Sci. USA(2012) 109(25), 9792-9297.
5.
Li, Guangtao*;Huang, Chengdong*,Zhao, Gang; Lennarz, William J. Interprotomer motion-transmission mechanism for the hexameric AAA ATPase p97. (*Equal contribution)Proc. Natl. Acad. Sci. USA(2012), 109(10), 3737-3741.
6.
Huang, Chengdong;Bhaskaran, Rajagopalan; Mohanty, Smita. Eukaryotic N-glycosylation Occurs Via membrane-anchored C-terminal domain of Stt3p subunit of oligosaccharyl transferase.J. Biol. Chem.(2012) 287(39), 32450-32458.
7.
Huang, Chengdong;Mohanty, Smita. Challenging the Limit: NMR Assignment of a 31 kDa Monomeric Helical Membrane Protein.J. Am. Chem. Soc.(2010), 132, 3662–3663.
8.
Huang, Chengdong;Mohanty, Smita, Bannerjee, Monimoy. A novel method of production and biophysical characterization of C-terminal domain of Stt3p, the catalyzing subunit of yeast Oligosaccharyl Transferase.Biochemistry (2010), 49, 1115–1126.