姜秀娥
单位：中国科学院长春应用化学研究所电分析化学国家重点实验室
地址：吉林省长春市人民大街5625号
邮编：130022
电话：
个人主页： https://www.x-mol.com/groups/jiang_xiue
实验室介绍：


个人简历 Personal resume


中国科学院长春应用化学研究所，电分析化学国家重点实验室，研究员教育经历： 2002/09 - 2005/12，中科院长春应化所，分析化学，博士，导师：董绍俊1999/09 - 2002/07，东北师范大学，分析化学，硕士，导师：郭黎平1995/09 - 1999/07，辽宁石油化工大学，化工工艺，学士工作经历： 2010/09 - 至今，中科院长春应化所，电分析化学国家重点实验室，研究员2010/01 - 2010/04， 德国 Karlsruhe 技术研究所，应用物理和纳米结构中心，博士后2008/06 - 2009/12，德国 ULM 大学，生物物理学院，博士后2006/04 - 2008/05，德国 Bielefeld 大学，化学系，洪堡****主持或参加科研项目及人才计划项目情况： 1、 国家自然科学基金****科学基金项目，谱学电化学分析，主持2、 国家自然科学基金优秀青年科学基金项目，纳米—生物相互作用的分析研究，主持3、 中国科学院科研仪器设备研制项目，超分辨荧光与纳米尺度红外成像显微镜，主持4、 国家自然科学基金国际合作项目，脑科学相关离子通道蛋白的调控机制及应用研究，主持5、 国家自然科学基金面上项目，纳米酶催化心磷脂过氧化双向调控细胞凋亡的基础研究及应用，主持6、 国家自然科学基金面上项目，氧化石墨烯类材料与肺表面活性剂作用的分子机理研究，主持


研究方向 Research direction


1、纳米生物效应的分子机理
2、生物界面分析
3、智能纳米材料的生物应用



招生信息 Enrollment information


办 公 室：无机分析楼504电话：8526-2378电子信箱：jiangxiue@ciac.ac.cn


论文专著 The monograph


1)Specific “unlocking” nanozyme-based butterfly effect for breaking the evolutionary fitness of chaotic tumor - Angewandte Chemie-International Edition - 2020 - 2020, 59(24), 9491-9497
2)The structure of water bonded to phosphate groups at the electrified zwitterionic phospholipid membranes/aqueous interface - Angewandte Chemie-International Edition - 2020 - 2020, 59(16), 6627-6630
3)Multi-caged IrOx for facile preparation of “six-in-one” nanoagent for subcutaneous and lymphatic tumors inhibition against recurrence and metastasis - Advanced Functional Materials - 2020 - 2020, 30(24), **
4)Specific generation of singlet oxygen through the russell mechanism in hypoxic tumors and GSH depletion by Cu-TCPP nanosheets for cancer therapy - Angewandte Chemie-International Edition - 2019 - 2019, 58(29), 9846-9850
5)BSA-IrO2: catalase-like nanoparticles with high photothermal conversion efficiency and a high X-ray absorption coefficient for anti-inflammation and antitumor theranostics - Angewandte Chemie-International Edition - 2018 - 2018, 57(32): 10309-10313
6)A facile ion-doping strategy to regulate tumor microenvironments for enhanced multimodal tumor theranostics - Journal of the American Chemical Society - 2018 - 2018, 140(1): 106-109
7)Revealing the nature of interaction between graphene oxide and lipid membrane by surface-enhanced infrared absorption spectroscopy - Journal of the American Chemical Society - 2015 - 2015, 137(32): 10052-10055
8) Molecular impact of the membrane potential on the regulatory mechanism of proton transfer in sensory rhodopsin II - Journal of the American Chemical Society - 2010 - 2010, 132(31): 10808-10815
9)Cellular uptake of nanoparticles by membrane penetration: a study combining confocal microscopy with FTIR - ACS Nano - 2012 - 2012, 6(2): 1251-1259
10)Endo- and exocytosis of zwitterionic quantum dot nanoparticles by live HeLa cells - ACS Nano - 2010 - 2010, 4(11): 6787-6797
11)MnO2 gatekeeper: an intelligent and O2-evolving shell for preventing premature release of high cargo payload core, overcoming tumor hypoxia, and acidic H2O2-sensitive MRI - Advanced Functional Materials - 2017 - 2017, 27(4): **
12)Resolving voltage-dependent structural changes of a membrane photoreceptor by surface-enhanced IR difference spectroscopy - PNAS - 2008 - 2008, 105(34): 12113-12117
13)Fe(III)-doped two-dimensional C3N4 nanofusiform: a new O2-evolving and mitochondria-targeting photodynamic agent for MRI and enhanced antitumor therapy - Small - 2016 - 2016, 12(39): 5477–5487
14)In situ surface-enhanced infrared absorption spectroscopy of aqueous molecules with facile-prepared large-area reduced graphene oxide island film - Analytical Chemistry - 2018 - 2018, 90(11), 6526-6531
15)Proton transfer at the interaction interface of graphene oxide - Analytical Chemistry - 2018 - 2018, 90 (17): 10223-10230
16)Revealing the effect of protein weak adsorption to nanoparticles on the interaction between the desorbed protein and its binding partner by surface-enhanced infrared spectroelectrochemistry - Analytical Chemistry - 2017 - 2017, 89 (5): 2724–2730
17)Analyzing structural properties of heterogeneous cardiolipin-bound cytochrome c and their regulation by surface-enhanced infrared absorption spectroscopy - Analytical Chemistry - 2016 - 2016, 88(23): 11727-11733
18)A facile one-pot synthesis of copper sulfide-decorated reduced graphene oxide composites for enhanced detecting of H2O2 in biological environments - Analytical Chemistry - 2013 - 2013, 85(17): 8095–8101