姓名：方泽民
邮箱：zemin_fang@163.com
职称：副教授，博士
联系电话：
地址：合肥市经开区九龙路111号安徽大学生命科学学院，合肥，安徽，中国
邮政编码：230601
2012年作为副教授优秀青年人才，进入安徽大学生命科学学院从事教学和研究工作。目前主持国家自然科学基金、教育部博士点基金、国家“863计划”子课题各1项，以及安徽省自然科学基金项目等4项。在国内外重要期刊发表学术论文20余篇。其中，作为第一作者/通讯作者在Biotechnology for Biofuels、Bioresource Technology、PLoS ONE、Applied Microbiology and Biotechnology等国际期刊发表SCI论文8篇，申报中国发明专利5项，获得授权3项。是Bioresource Technology、Enzyme and Microbial Technology等多个杂志的审稿人。
主要研究方向：
1.新颖性质新型工业用酶的发现及制备
2.芳香族化合物诱导及真菌互作过程中的真菌漆酶差异表达调控机制

主持在研项目：
1.安徽省教育厅自然科学基金重大项目，“Hsp70家族成员ThHspA1功能研究”（KJ2017ZD04）
2.国家自然科学基金，“共培养条件下灰盖鬼伞菌漆酶Lcc9表达的转录调控机制”(**)
3.教育部高等学校博士学科点专项科研基金（新教师类），“真菌相互作用过程中灰盖鬼伞菌Lcc9功能研究”(20**0)
4.国家863计划子课题，“远海大型生物全新天然产物的发现及药物先导化合物的优化”(2013AA092901)
5.安徽省自然科学基金，“真菌相互作用诱导漆酶表达核心转录因子研究”(**QC46)
6.安徽省教育厅自然科学基金重点，“乙醇耐受的新型真菌漆酶筛选”(KJ2013A022)
7.安徽大学人才引进启动基金
发表文章：
1.Zhang YF, Xu Y, Fang W, Wang XT, Fang ZM*, Xiao YZ.Pseudoruegeriamarinistellae sp. nov.,isolated from an unidentified starfish in Sanya, China.Antonie van Leeuwenhoek, 2017, 110, 187-194 (*Corresponding author)
2.Zhang YF, Tang PP, Xu Y, Fang W, Wang XT,Fang ZM*, Xiao YZ*.Lutimaribactermarinistellae sp. nov., isolated from a starfish.Int J Sys EvoMicrob, 2016, 66: 3675-3680, doi: 10.1099/ijsem.0.001251. (*Corresponding author)
3.Fang W, Yang Y, Zhang XX, Yin Q, Zhang XB, Wang XT, Fang ZM*, Xiao YZ*. Improve ethanol tolerance of β-glucosidase Bgl1A by semi-rational engineering for the hydrolysis of soybean isoflavone glycosides. J Biotechnol, 2016, 227,64-71. (*Corresponding author)
4.Chen L, Yi XM, Deng FJ, Fang W, Zhang XC, Wang XT,Fang ZM*, Xiao YZ. A novel ethanol-tolerant laccase, Tvlac, from Trametes versicolor. Biotech Lett, 2016, 38:471-476. (*Corresponding author)
5.He C, Li J, Li W, Xue Y, Fang ZM, Fang W, Zhang XC, Wang XT, Xiao YZ. Structures of PspAG97A α-glucoside hydrolase reveal a novel mechanism for chloride induced activation. J StruBiol, 2016, 196: 426-436
6.Li W, Fan H, He C, Zhang XC, Wang XT, Yuan J, Fang ZM, Fang W, Xiao YZ. PspAG97A: a halophilic α-glucoside hydrolase with novel substrate specificity from glycoside hydrolase family 97. J MicrobiolBiotechnol,2016, 26(11): 1933-1942
7.Li W, Xue Y, Li J, Yuan J, Wang X, Fang W, Fang Z*, Xiao Y. A cold-adapted and glucose-stimulated type II α-glucosidase from a deep-sea bacterium Pseudoalteromonas sp. K8. Biotech Lett, 2016, 38:345-349. (*Corresponding author)
8.Yang Y, Zhang X, Yin Q, Fang W, Fang Z, Wang X, Zhang X, Xiao Y. A mechanism of glucose tolerance and stimulation of GH1 β-glucosidases. Sci Rep, 2015. 5:17296 DOI: 10.1038/srep17296
9.Wang J, Zhang Y, Xu Y, Fang W, Wang X,Fang Z*, Xiao Y*. Genome sequence of a laccase producing fungus Trametes sp. AH28-2. J Biotechnol, 2015, 216, 167-168. (*Corresponding author)
10.Fang Z, Liu X, Chen L, Shen Y, Zhang X, Fang W, Wang X, Bao X, Xiao Y. Identification of a laccase Glac15 from Ganodermalucidum 77002 and its application in bioethanol production. Biotech Biofuel, 2015, 8:54 DOI 10.1186/s13068-015-0235-x
11.Fang W, Song R, Zhang X, Zhang X, Zhang X, Wang X, Fang Z*, Xiao Y*. Characterization of a novel β-glucosidase from Gongronella sp. W5 and its application in the hydrolysis of soybean isoflavone glycosides. J Agric Food Chem2014, 62, 11688-11695. (*Corresponding author)
12.Fang ZM, Zhou P, Chang F, Yin Q, Fang W, Yuan J, Zhang XC, Xiao YZ. Structure-based rational design to enhance the solubility and thermostability of a bacterial laccase Lac15. 2014, PLoS ONE 9(7): e102423. doi:10.1371/journal.pone.**
13.Fang ZM*, Li JJ*, Wang Q, Fang W, Peng H, Zhang XC, XiaoYZ. A novelesterase from a marine metagenomic library exhibiting salt tolerance ability. J MicrobiolBiotechnol, 2014, 24(6), 771-780. (* co-first author)
14.Pan K, Zhao NN, Yin Q, Zhang TW, Xu XL, Fang W, Hong YZ, Fang ZM*, Xiao YZ. Induction of laccase Lcc9 from Coprinopsis cinereaby fungal coculture and its application on indigo dye decolorization. BioresourTechnol, 2014, 162: 45-52. (*Corresponding author)
15.Fang W*,Fang ZM*,Liu ZM, Yuan J, Zhang XC, Peng H, Hong YZ, Xiao YZ. Phylogenetic analysis of bacterial community in the gut of American cockroach (Periplanetaamericana). ActaMicrobiologicaSinica, 2013, 53: 984-994. (* co-first author)
16.Fang ZM*,Li TL*, Chang F, Zhou P, Fang W, Hong YZ, Zhang XC, Peng H, Xiao YZ. A new marine bacterial laccase with chloride-enhancing, alkaline-dependent activity and dye decolorization ability. BioresourTechnol, 2012, 111: 36-41. (* co-first author)
17.Fang W*,Fang ZM*, Zhou P, Chang F, Hong YZ, Zhang XC, Peng H, Xiao YZ. Evidence for lignin oxidation by the giant panda fecal microbiome. PLoS ONE, 2012, 7(11): e50312. (* co-first author)
18.Fang ZM, Li TL, Chang F, Zhou P, Fang W, Hong YZ, Zhang XC, Peng H, Xiao YZ. A bacterial laccase from marine microbial metagenome exhibiting chloride tolerance and dye decolorization ability. ApplMicrobiolBiotechnol, 2011, 89: 1103-1110.
19.Liu JJ, Zhang XC, Fang ZM, Fang W, Peng H, Xiao YZ. The 184th residue of β-glucosidaseBgl1B plays an important role in glucose tolerance. J BiosciBioeng, 2011, 112: 447-450.
20.GeHH, Xu PS, Xu Y, Fang ZM, Xiao YZ. Purification, crystallization and preliminary crystallographic analysis of recombinant Lac15 from a marine microbial metagenome. ActaCryst F, 2011, 67: 956-958.
21.Fang ZM, Fang W, Liu JJ, Hong YZ, Peng H, Zhang XC, Sun BL, Xiao YZ. Cloning and characterization of a β-glucosidase from marine microbial metagenome with excellent glucose tolerance. J MicrobiolBiotechnol, 2010, 20: 1351-1358.