计山明
性别:
男
专业名称:
分子生物学
研究方向:
免疫稳态与衰老长寿
技术职务:
教授
E-mail:
jismahau.edu.cn
通讯地址:
安徽农业大学生物科技楼
邮政编码:
230036
计山明,博士,教授,博士生导师,2017年安徽农业大学高层次引进人才。
主讲课程:
《分子生物学》
教育与工作经历:
(1) 2005年9月至2009年6月 武汉大学生命科学学院 学士
(2) 2009年9月至2015年1月 中国科学院动物研究所 博士
(3) 2015年7月至2017年7月 安徽农业大学生命科学学院 博士后
(4) 2017年8月至今 安徽农业大学生命科学学院 教授
研究方向:
(1)天然免疫信号传导的调控机理
(2)蛋白质液-液相分离的调控机理
科研项目:
(1) 瑞士Ferring合作项目,FIRMA200501,2020-2025,主持
(2) 安徽省****科学基金项目,**J14,2020-2022,主持
(3)国家自然科学基金面上项目,**,2019-2022,主持
(4) 安徽农业大学人才引进项目,**,2017-2022,主持
(5) 中国博士后基金面上项目,2017M612053,2017-2018,主持
发表文章:
(1) Shanming Ji#, Yuewan Luo#, Qingshuang Cai#, Zhijie Cao,Yuanyuan Zhao,Jie Mei,Chenxiao Li, Pengyan Xia,Zhongwen Xie,Zongping Xia,Jian Zhang,Qinmiao Sun*, Dahua Chen*.LC domain-mediated coalescenceis essential for Otu enzymatic activity to extendDrosophilalifespan. Molecular Cell. 2019.03.14, 74: 1~15. (IF=15.584)
(2) Shanming Ji#, Chaoyi Li#, Lin Hu#, Kehui Liu, Jie Mei, Yuewan Luo,Yi Tao, Zongping Xia, Qinmiao Sun, Dahua Chen*. Bam-dependentdeubiquitinase complex can disrupt germ-line stem cell maintenance by targeting cyclin A. PNAS. 2017.6.13, 114(24): 6316~6321. (IF=9.412)(3) Shanming Ji#, Ming Sun#, Xiudeng Zheng#, Lin Li, Liwei Sun, Dahua Chen*, Qinmiao Sun*. Cell-surface localization of Pellino antagonizes Toll-mediated innate immune signalling by controlling MyD88 turnover in Drosophila. Nature Communications. 2014.3.17, 5(3458): 1~14. (IF=12.121)
(4) Qingshuang Cai#, Shanming Ji#, Mengwan Li, Sen Zheng, Xiuhong Zhou, Huimin Guo, Siyu Deng, Junyan Zhu, Daxiang Li, Zhongwen Xie.Theaflavin-regulated Imd condensates control Drosophila intestinal homeostasis and aging. iScience. 2021.2.6,24(3):102150. (IF=4.447)
(5)Qingshuang Cai, Shanming Ji, Yue Sun, Linsheng Yu, xianli Wu*, Zhongwen Xie*. 10-Hydroxy-trans-2-decenoic acid attenuates angiotensin II-induced inflammatory responses in rat vascular smooth muscle cells. Journal of Functional Foods. 2018.4.14, 10(1016). (IF=3.701)
(6) Wenqing Li, Weini Li, Lihui Zou,Shanming Ji, Chaoyi Li, KehuiLiu, Guoqiang Zhang, Qinmiao Sun, Fei Xiao*, Dahua Chen*. Membranetargeting of inhibitory Smads through palmitoylation controls TGF-β/BMP signaling. PNAS. 2017.11.3, 10(1073).(IF=9.412)
(7) Chaoyi Li, Lijuan Kan, Yan Chen, Xiudeng Zheng, Weini Li, Wenxin Zhang,Lei Cao, Xiaohui Lin, Shanming Ji, Shoujun Huang, Guoqiang Zhang,Xiaohui Liu, Yi Tao; Shian Wu*, Dahua Chen*.Ci antagonizes Hippo signaling in the somatic cells of the ovary to drive germline stem cell differentiation. Cell Research. 2015.9.25, 10(1038). (IF=20.507)
(8) Yali Tang, Yang Wang, Shanming Ji, Kundi Zhang, Jun Dai, Lei Zhang, Fang Peng, Chengxiang Fang*. Pedobacter xinjianggensis sp. nov., from desert, Xinjiang. J Microbiol Biotechnol. 2010 Feb;20(2):397-402. (IF=1.992)
(9)Yali Tang, Jun Dai, Lei Zhang, Zhongying Mo, Yang Wang, Yaowei Li, Shanming Ji, Chengxiang Fang*, Congyi Zheng*. Dyadobacter alkalitolerans sp. nov., isolated from desert sand. Int J Syst Evol Microbiol. 2009 Jan;59(Pt 1):60-4. (IF=2.415)