李长生


性别：
男
单位：
生命科学学院
专业名称：
遗传学

研究方向：
作物基因组学

技术职务：
教授

E-mail：
csliahau.edu.cn

通讯地址：
安徽农业大学生物科技楼425

邮政编码：
230036

李长生，博士，教授，博导。2018年获得沈阳农业大学农学博士学位，同年进入中国科学院分子植物科学卓越创新中心博士后流动站工作。博士及博后期间主要利用遗传学，比较基因组学以及转录组学等多组学手段解析农作物玉米在胚乳发育过程中淀粉和蛋白质表达调控网络，为改善玉米种子的淀粉与蛋白的分配平衡和优良品质提供理论基础。2020年12高层次引进人才进入安徽农业大学生命科学学院工作。近年来相关研究成果分别发表在《Nature Communications》《Plant Biotechnology Journal 》《Plant Cell》《PNAS 》《Frontiers in plant science》等国内外学术期刊上。

　研究兴趣：

1.基于多组学及基因编辑手段研究结构变异对玉米品质性状的影响
2.基于表观基因组学研究非编码区远端调控对功能基因的影响

　教育与工作经历：

教育经历
2014/09 - 2018/07 博士（联合培养），作物学，沈阳农业大学，
中国科学院分子植物科学卓越创新中心和上海交通大学，导师：黄瑞冬，
巫永睿，王文琴
2011/09 - 2014/07，硕士，发育生物学，沈阳农业大学，导师：林
凤
2007/09 - 2011/07，学士，生物科学，沈阳农业大学
工作经历
2020/12 - 至今，教授， 安徽农业大学生命科学学院
2018/09 - 2020/12，上海市超级博士后，中国科学院分子植物科学卓越创新中心，合作导师：巫永睿

　科研项目：

1. 上海市“超级博士后”激励计划项目经费资助，优质蛋白玉米基因组的三代测序组装与
o2修饰因子的挖掘，主持。
2. 中国博士后基金会第66 批面上资助项目， 优质蛋白玉米胚乳修饰因子的组学和遗
传学解析，主持。

　论文论著：

1.Changsheng Li, Xiaoli Xiang, Yongcai Huang, Yong Zhou, Dong An, Jiaqiang
Dong, Chenxi Zhao, Hongjun Liu, Yubin Li, Qiong Wang, Chunguang Du,
Joachim Messing, Brian A. Larkins, Yongrui Wu, Wenqin Wang. 2020. Longread
sequencing reveals genomic structural variations that underlie creation of
Quality Protein Maize. Nature Communications, 11(1): 1-11.
2.Changsheng Li, Yongcai Huang, Ruidong Huang, Yongrui Wu and Wenqin
Wang. 2017.The Genetic Architecture of Amylose Biosynthesis in Maize Kernel.
Plant Biotechnol J, 16(2): 688-695.
3.Changsheng Li, Feng Lin, Dong An, Wenqin Wang and Ruidong Huang. 2017.
Genome Sequencing and Assembly by Long Reads in Plants. Genes, 9(1): 6.
4. Xiaoli Xiang, andChangsheng Li. Strategies and Tools for Sequencing
Duckweeds. The Duckweed Genomes. Springer, Cham, 2020. 67-75.
5. Dong An, Yong Zhou,Changsheng Li, Qiao Xiao, Tao Wang, Yating Zhang,
Yongrui Wu, Yubin Li, Dai-Yin Chao, Joachim Messing, and Wenqin Wang.
2019. Plant evolution and environmental adaptation unveiled by long-read
whole-genome sequencing of Spirodela. Proceedings of the National Academy
of Sciences, 116 (38) :18893-18899.
6. Xixi Zheng, Qi Li,Changsheng Li, Dong An, Qiao Xiao, Wenqin Wang,
Yongrui Wu. 2019. Intra-Kernel Reallocation of Proteins in Maize Depends on
VP1-Mediated Scutellum Development and Nutrient Assimilation. The Plant
Cell, 31(11): 2613–2635.
7. Haihai Wang, Yongcai Huang, Qiao Xiao, Xing Huang,Changsheng Li,
Xiaoyan Gao, Qiong Wang, Xiaoli Xiang, Yidong Zhu, Jiechen Wang, Wenqin
Wang, Brian A. Larkins, Yongrui Wu. 2020. Carotenoids modulate kernel
texture in maize by influencing amyloplast envelope integrity. Nature
communications, 11(1), 1-13.
8. Qi Li, Jiechen Wang, Jianwei Ye, Xixi Zheng, Xiaoli Xiang,Changsheng Li,
Miaomiao Fu, Qiong Wang, Zhiyong Zhang and Yongrui Wu. 2017. The Maize
Imprinted Gene Floury3 Encodes a PLATZ Protein Required for tRNA and 5S
rRNA Transcription through Interaction with RNA Polymerase III. The Plant
Cell, 29(10): 2661-2675.
9. Hongjun Liu, Junpeng Shi, Chuanlong Sun, Hao Gong, Xingming Fan, Fazhan
Qiu, Xuehui Huang, Qi Feng,Xixi Zheng, Ningning Yuan,Changsheng Li,
Zhiyong Zhang, Yiting Deng, Jiechen Wang, Guangtang Pan,Bin Han, Jinsheng
Lai and Yongrui Wu. 2016. Gene duplication confers enhanced expression of 27-
kDa γ-zein for endosperm modification in quality protein maize. Proceedings of
the National Academy of Sciences, 113(18): 4964-4969.
10. Dong An, Hieu X. Cao,Changsheng Li, Klaus Humbeck and Wenqin Wang.
2018. Isoform Sequencing and State-of-Art Applications for Unravelling
Complexity of Plant Transcriptomes. Genes, 9(1):43.
11. Hongjun Liu, Lin Zhang, Jiechen Wang,Changsheng Li,Xing Zeng, Shupeng
Xie,Yongzhong Zhang, Sisi Liu, Songlin Hu, Jianhua Wang, Michael
Lee,Thomas Lübberstedt and Guangwu Zhao. 2017. Quantitative Trait Locus
Analysis for Deep-Sowing Germination Ability in the Maize IBM Syn10 DH
Population. Frontiers in plant science,8(813):1-12.
12. Dong An,Changsheng Li, Yongrui Wu, Wenqin Wang. 2018.Genomes and
transcriptomes of duckweeds. Frontiers in chemistry, 6: 230.
13. Yating Zhang, Dong An,Changsheng Li, Zhixuan Zhao, Wenqin Wang. 2020.
The complete chloroplast genome of greater duckweed (Spirodela polyrhiza 7498)
using PacBio long reads: insights into the chloroplast evolution and transcription
regulation. BMC Genomics, 21(1), 76.