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浙江工业大学理学院导师教师师资介绍简介-孙李真

本站小编 Free考研考试/2021-04-10


孙李真,浙江临安人,党员,博士,博后,副教授,硕导。


一、教育与工作经历:
2004-2008,本科,浙江大学,物理学系
2008-2013,博士,浙江大学,物理学系凝聚态所
2013至今,教师,浙江工业大学,理学院
2015-2017,博士后,美国密苏里大学,天文与物理学院


二、主要研究领域:
(1) 生物高分子的移位运动。生物高分子通过纳米管道(或小孔)从一个空间到另一个空间的运动被称为高分子的移位运动。高分子移位在生物系统以及技术应用方面都有非常重要的作用,因此已成为二十年来研究热点之一。
(2) 生物高分子的离子结合效应。生物高分子(如DNA和RNA分子)需要结合离子屏蔽/中和其骨架电子排斥以折叠为正确的三维结构,才能展现出生物意义。因此,研究离子结合效应对我们预测生物高分子的结构并理解其生物作用有非常重要的意义。


三、主持项目
1. 国家自然科学基金青年项目,**,RNA折叠及对接过程中离子复杂结合效应的研究,2018/01-2020/12,25万元,在研
2. 浙江省自然科学基金一般项目,LQ14A040004,利用移位运动进行生物大分子测序的模拟研究,2014/01-2016/12,5万元,结题


四、近几年论文著作
[1] Jia Chen, Xian Chen,Li-Zhen Sun, Xiaojun Xu, Meng-Bo Luo. Translocation of a looped polymer threading through a nanopore. Soft Matter. 2021, DOI: 10.1039/d1sm00007a(通讯作者)
[2] Li-Zhen Sun, Wei-Ping Cao, Chang-Hui Wang, Xiaojun Xu. The translocation dynamics of the polymer through a conical pore: Non-stuck, weak-stuck, and strong-stuck modes. J. Chem. Phys. 2021, 154, 054903.
[3] Li-Zhen Sun, Yangwei Jiang, Yuanzhe Zhou, Shi-Jie Chen. RLDOCK: A new method for predicting RNA-ligand interactions. J. Chem. Theory Comput. 2020, 16, 7173-7183.
[4] Chang-Hui Wang, Meng-Bo Luo, Xiaojun Xu, Cao Wang, Li-Zhen Sun. Effects of salt concentration on the polyelectrolyte translocation through a cylinder nanopore. Eur. Polym. J.2019, 121, 109332.(通讯作者)
[5] Li-Zhen Sun,Yuanzhe Zhou, Shi-Jie Chen. Predicting monovalent ion correlation effects in nucleic acids. ACS Omega, 2019, 4, 13435-13446.
[6] Li-Zhen Sun, Qingmiao Nie, Haibin Li. Randomness of eigenstates of many-body quantum systems. Entropy, 2019, 21, 227.
[7] Li-Zhen Sun, Shi-Jie Chen. Predicting RNA-metal ion binding with ion dehydration effects.Biophys.J., 2019, 116, 184-195.
[8] Li-Zhen Sun, Chang-Hui Wang, Meng-Bo Luo, Haibin Li. Trapped and non-trapped polymer translocations through a spherical pore. J. Chem.Phys., 2019, 150, 024904.
[9] Li-Zhen Sun, Haibin Li, Xiaojun Xu, Meng-Bo Luo. Simulation study on the translocation of polyelectrolyte through conical nanopores.J. Phys.: CondensedMatt., 2018, 30, 495101.
[10] Li-Zhen Sun, Meng-Bo Luo, Wei-Ping Cao, Haibin Li.Theoretical study on the polymer translocation into an attractive sphere. J. Chem.Phys., 2018, 149, 024901.
[11] Li-Zhen Sun, Clayton Kranawetter, Xiao Heng, Shi-Jie Chen.Predicting ion effects in an RNA conformational equilibrium. J.Phys.Chem.B, 2017, 121, 8026-8036.
[12] Li-Zhen Sun, Jing-Xiang Zhang, Shi-Jie Chen.MCTBI: Aweb server for predicting metal ion effects in RNA structures. RNA, 2017, 23, 1155-1165.
[13]Li-Zhen Sun, Dong Zhang, Shi-Jie Chen. Theory and modeling of RNA structure and interactions with metal ions and small molecules. Annu.Rev.Biophys.,2017, 46, 227-246.
[14]Li-Zhen Sun, Xiao Heng, Shi-Jie Chen. Theory meets experiment: Metal ion effects in HCV genomic RNA kissing complex formation.Front. Mol. Biosci.,2017, 4, 92.
[15] Li-Zhen Sun, Shi-Jie Chen.Monte Carlo tightly bound ion model: Predicting ion-binding properties of RNA with ion correlations and fluctuations. J.Chem.Theory Comput.,2016, 12, 3370








教师简介
孙李真
孙李真,浙江临安人,党员,博士,博后,副教授,硕导。


一、教育与工作经历:
2004-2008,本科,浙江大学,物理学系
2008-2013,博士,浙江大学,物理学系凝聚态所
2013至今,教师,浙江工业大学,理学院
2015-2017,博士后,美国密苏里大学,天文与物理学院


二、主要研究领域:
(1) 生物高分子的移位运动。生物高分子通过纳米管道(或小孔)从一个空间到另一个空间的运动被称为高分子的移位运动。高分子移位在生物系统以及技术应用方面都有非常重要的作用,因此已成为二十年来研究热点之一。
(2) 生物高分子的离子结合效应。生物高分子(如DNA和RNA分子)需要结合离子屏蔽/中和其骨架电子排斥以折叠为正确的三维结构,才能展现出生物意义。因此,研究离子结合效应对我们预测生物高分子的结构并理解其生物作用有非常重要的意义。


三、主持项目
1. 国家自然科学基金青年项目,**,RNA折叠及对接过程中离子复杂结合效应的研究,2018/01-2020/12,25万元,在研
2. 浙江省自然科学基金一般项目,LQ14A040004,利用移位运动进行生物大分子测序的模拟研究,2014/01-2016/12,5万元,结题


四、近几年论文著作
[1] Jia Chen, Xian Chen,Li-Zhen Sun, Xiaojun Xu, Meng-Bo Luo. Translocation of a looped polymer threading through a nanopore. Soft Matter. 2021, DOI: 10.1039/d1sm00007a(通讯作者)
[2] Li-Zhen Sun, Wei-Ping Cao, Chang-Hui Wang, Xiaojun Xu. The translocation dynamics of the polymer through a conical pore: Non-stuck, weak-stuck, and strong-stuck modes. J. Chem. Phys. 2021, 154, 054903.
[3] Li-Zhen Sun, Yangwei Jiang, Yuanzhe Zhou, Shi-Jie Chen. RLDOCK: A new method for predicting RNA-ligand interactions. J. Chem. Theory Comput. 2020, 16, 7173-7183.
[4] Chang-Hui Wang, Meng-Bo Luo, Xiaojun Xu, Cao Wang, Li-Zhen Sun. Effects of salt concentration on the polyelectrolyte translocation through a cylinder nanopore. Eur. Polym. J.2019, 121, 109332.(通讯作者)
[5] Li-Zhen Sun,Yuanzhe Zhou, Shi-Jie Chen. Predicting monovalent ion correlation effects in nucleic acids. ACS Omega, 2019, 4, 13435-13446.
[6] Li-Zhen Sun, Qingmiao Nie, Haibin Li. Randomness of eigenstates of many-body quantum systems. Entropy, 2019, 21, 227.
[7] Li-Zhen Sun, Shi-Jie Chen. Predicting RNA-metal ion binding with ion dehydration effects.Biophys.J., 2019, 116, 184-195.
[8] Li-Zhen Sun, Chang-Hui Wang, Meng-Bo Luo, Haibin Li. Trapped and non-trapped polymer translocations through a spherical pore. J. Chem.Phys., 2019, 150, 024904.
[9] Li-Zhen Sun, Haibin Li, Xiaojun Xu, Meng-Bo Luo. Simulation study on the translocation of polyelectrolyte through conical nanopores.J. Phys.: CondensedMatt., 2018, 30, 495101.
[10] Li-Zhen Sun, Meng-Bo Luo, Wei-Ping Cao, Haibin Li.Theoretical study on the polymer translocation into an attractive sphere. J. Chem.Phys., 2018, 149, 024901.
[11] Li-Zhen Sun, Clayton Kranawetter, Xiao Heng, Shi-Jie Chen.Predicting ion effects in an RNA conformational equilibrium. J.Phys.Chem.B, 2017, 121, 8026-8036.
[12] Li-Zhen Sun, Jing-Xiang Zhang, Shi-Jie Chen.MCTBI: Aweb server for predicting metal ion effects in RNA structures. RNA, 2017, 23, 1155-1165.
[13]Li-Zhen Sun, Dong Zhang, Shi-Jie Chen. Theory and modeling of RNA structure and interactions with metal ions and small molecules. Annu.Rev.Biophys.,2017, 46, 227-246.
[14]Li-Zhen Sun, Xiao Heng, Shi-Jie Chen. Theory meets experiment: Metal ion effects in HCV genomic RNA kissing complex formation.Front. Mol. Biosci.,2017, 4, 92.
[15] Li-Zhen Sun, Shi-Jie Chen.Monte Carlo tightly bound ion model: Predicting ion-binding properties of RNA with ion correlations and fluctuations. J.Chem.Theory Comput.,2016, 12, 3370




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