个人主页
平平安安
summary
姓名：谢强敏
\r性别：男
\r出生地：杭州
\r所属学科：药理学
\r现任职务：国家食品药品监督管理局浙江呼吸药物研究实验室副主任
\r联系方式：
\r电话：**，**
\rE-mail：xieqm@zju.edu.cn
\r学术团体、专业杂志编委和审稿：
\r中国药理学会抗炎免疫药理专业委员会理事
\r中国药理学会制药工业药理专业委员会理事
\r浙江省生理科学专业委员会常务理事
\r浙江省药理学专业委员会理事
\r世界临床药物杂志编委
\rActa Pharmacol Sin.审稿
\rEur J Pharmacol审稿
\rJ Pharm Pharmacol审稿
\rTrends in Pharmacol审稿
\r学科专长和研究方向: 呼吸药理学，免疫药理学，新药研究
\r主持和参与的课题：
\r1.国家自然科学基金项目（2008.01—2010.12）：Rho GTPase Rac作为治疗COPD新靶点的研究
\r2.国家自然科学基金项目（2007.01—2009.12）：5-酯氧酶代谢物对哮喘的神经内分泌免疫调节作用
\r3.浙江省科技计划重点项目（2006.03—2008.12）：甘草黄酮的开发与研究
\r4.浙江省科技计划重点项目（2007.05—2009.12）：虫草头孢菌粉抗心律失常的有效成分及其作用机制研究
\r5.浙江省自然科学基金重点项目 (2005.01—2007.12)：磷酸二酯酶-4在肺部炎症疾病的作用
\r一、著作（主编1部，副主编1部，参编7部）
\r1.主编 《药理学前沿－哮喘和COPD的新概念及新药》, 专著, 2003.8, 科学出版社
\r2.第二副主编《生理科学实验教程》, 精品课程教材, 2004.8, 浙江大学出版社
\r3.参编《免疫药理学新论》, 专著, 2004.5, 人民卫生出版社
\r4.参编《抗衰老药理学新论》,专著, 2004.5, 人民卫生出版社
\r5.参编《呼吸药理学新论》,专著, 2004.5, 人民卫生出版社
\r6.参编《药理实验方法学》第三版，专著, 2004.5, 人民卫生出版社
\r7.参编《药理学和药物治疗学全书》，编著，2000，人民卫生出版社
\r8.参编《中药药理与临床》，编著，2000，人民卫生出版社
\r9.参编《呼吸药理学与治疗学》，专著, 1999, 人民卫生出版社
\r10.参编《临床药理学》，2007，人民卫生出版社
\r二、主要论文
\r1.Wu X, Zeng LH, Taniguchi T, Xie QM（通讯作者）. Activation of PKA and phosphorylation of sodium-dependent vitamin C transporter 2 by prostaglandin E2 promote osteoblast-like differentiation in MC3T3-E1 cells. Cell Death Differ. 2007;14(10):1792-1801.(IF=7.463)
\r2.Deng YM, Xie QM（通讯作者）, Zhang SJ et al. Anti-astnmatic eeffects of Perilla Seed oil in the guinea pig in vitro and in vivo. Planta Med 2007; 73(1):53-58. IF=1.746
\r3.Deng YM, Xie QM（通讯作者）, Tang HF, Sun JG, Deng JF, Chen JQ, Yang SY. Effects of ciclamilast, a new PDE 4 inhibitor, on airway hyperresponsiveness, PDE4D expression and airway inflammation in a murine model of asthma. Eur J Pharmacol. 2006 Oct 10;547(1-3):125-35. IF=2,522
\r4.Sun JG, Deng YM, Wu X, Tang HF, Deng JF, Chen JQ, Yang SY, Xie QM（通讯作者）.Inhibition of phosphodiesterase activity, airway inflammation and hyperresponsiveness by PDE4 inhibitor and glucocorticoid in a murine model of allergic asthma. Life Sci. 2006 Oct 26;79(22):2077-2085. IF=2.389
\r5.Xie QM（通讯作者）, Deng JF, Deng YM, Shao CS, Zhang H, Ke CK. Effects of cryptoporus polysaccharide on rat allergic rhinitis associated with inhibiting eotaxin mRNA expression. J Ethnopharmacol. 2006 Oct 11;107(3):424-30. IF=1.625
\r6.Tang HF, Chen JQ, Xie QM, Zheng XY, Zhu YL, Adcock I, Wang X.The role of PDE4 in pulmonary inflammation and goblet cell hyperplasia in allergic rats. Biochim Biophys Acta. 2006 May;1762(5):525-32. IF=3.297
\r7.Zhou HL, Deng YM, Xie QM（通讯作者）. The modulatory effects of the volatile oil of ginger on the cellular immune response in vitro and in vivo in mice. J Ethnopharmacol. 2006 Apr 21;105(1-2):301-5.. IF=1.625
\r8.Xu XL, Zhou JY, Yang QH,Fang LB, Xie QM, Shen YL. An in vitro rat diaphragmatic fatigue model induced by combined hypoxic and hypercapnic acidosis and the effect of salmeterol. Pharmacol Res 2006 Feb 53 (2): 171-176 IF=2.421
\r9.Deng YM, Xie QM（通讯作者）, Zhang SJ, Chen JQ, Yang QH, Bian RL. Changes of 5-lipoxygenase pathway and proinflammatory mediators in cerebral cortex and lung tissue of sensitized rats. Acta Pharmacol Sin. 2005 Mar;26(3):353-8. IF=1.397
\r10.Chen JC, Chen JQ, Xie QM, Zhu YL. Selective inhibition of purified human phosphodiesterase 4A expressed in yeast cell GL62 by ciclamilast, piclamilast, and rolipram.Acta Pharmacol Sin. 2004 Sep;25(9):1171-5. IF=1.397
\r11.Zhao XY, Xie QM（通讯作者）, Chen JQ, Ke CK.Inhibitory effects of cryptoporus polysaccharide on airway constriction,eosinophil release, and chemotaxis in guinea pigs. Acta Pharmacol Sin. 2004 Apr;25(4):503-7. IF=1.397
\r12.Deng YM, Xie QM（通讯作者）, Chen JQ, Bian RL.Coincidental increase of leukotriene B4 between cerebral cortex and lung tissue of sensitized rats. Acta Pharmacol Sin. 2003 Oct;24(10):1039-44. IF=1.397
\r13.Zhou J, Kang ZM, Xie QM, Liu C, Lou SJ, Chen YZ, Jiang CL. Rapid nongenomic effects of glucocorticoids on allergic asthma reaction in the guinea pig. J Endocrinol. 2003 Apr;177(1):R1-4. IF=3.072
\r14.Xie QM（通讯作者）, Chen JQ, Shen WH, Yang QH, Bian RL.Comparison of bronchodilating and antiinflammatory activities of oral formoterol and its (R,R)-enantiomers. Acta Pharmacol Sin. 2003 Mar;24(3):277-82. IF=1.397
\r15.Xie QM , Chen Ying, Wu Xi-mei, Chen Ji-qiang, Bian Ru-lian. Mechanism of the Effect of Santengdingtong Recipeon Monosodium Urate Crystal-Induced Rabbit Arthritis. Chinese Journal of Integrated Medicine，2003；9（2）：128-131
\r16.Xie QM（通讯作者）, Tang HF, Chen JQ, Bian RL.Pharmacological actions of tetrandrine in inflammatory pulmonary diseases. Acta Pharmacol Sin. 2002 Dec;23(12):1107-13. Review. IF=1.397
\r17.Xie QM（通讯作者）, Chen JQ, Shen WH, Bian RL.Correlative changes of interferon-gamma and interleukin-4 between cortical layer and pulmonary airway of sensitized rats. Acta Pharmacol Sin. 2002 Mar;23(3):248-52. IF=1.397
\r18.Xie QM（通讯作者）, Chen JQ, Shen WH, Yang QH, Bian RL. Effects of cyclosporin A by aerosol on airway hyperresponsiveness and inflammation in guinea pigs. Acta Pharmacol Sin. 2002 Mar;23(3):243-7. IF=1.397
\r19.Xie QM（通讯作者）, Zeng LH, Zheng YX, Lu YB, Yang QH. Bronchodilating effects of bambuterol on bronchoconstriction in guinea pigs.Acta Pharmacol Sin.1999 Jul;20(7):651-4. IF=1.397
\r近2年参加重要国际学术会议大会发言和论文摘要
\r1.Xie QM, Deng YM, Chen JQ. The neuro-endocrine-immumo regulation of 5-lipoxygenase in the asthmatic model of rats. XVth World Congress of Pharmacology: Meeting Abstract P 340059, July 2-7, 2006
\r2.Tang HF, Chen JQ, Xie QM. Upregulation of PDE4 activity and expression in lung of asthmatic rats. XVth World Congress of Pharmacology: Meeting Abstract P 340053
\r3.Deng YM, Xie QM, Chen JQ, Zhang SJ, Yao HY, Zhang H. Anti-asthma effects of perilla seed oil in the guinea pig in vivo and vitro. XVth World Congress of Pharmacology: Meeting Abstract P 340065, July 2-7, 2006
\r4.Li ZG, Xie QM, Yin ZQ, Tang HF, Chen JQ. Inhibitory effects of local anesthetis on contractions of pregnant rat myometrium. XVth World Congress of Pharmacology: Meeting Abstract P 340076, July 2-7, 2006
\r5.Chen JQ, Xia Q, Xie QM, Wei EQ, Fu LQ. Pharmacology in the integrated course “Basic Medical Sciences” in Zhejiang University of School of Medicine. XVth World Congress of Pharmacology: Meeting Abstract P 410007, July 2-7, 2006
\r6.Xie QM, Hu HM, Zhu YL, Zhang SJ, Chen JQ. Desensitization effect of sublingul immunotherapy on the dust mite sensitized rats. Abstracts presented at concurrent aessions. Annual Scientific Meeting of the American College of Allergy,Asthma&Immunology 2005, november 4-9, Abstract Book p 50.
\r7.Xie QM, Deng YM, Sun JG, Tang HF, Deng JF, Chen JQ. Effects of Ciclamilast, a new PDE4 inhibitor, on upregulation of PDE4, airway mucus hypersecretion and airway hyperresponsiveness in mouse asthmatis model. Annual Scientific Meeting of the American College of Allergy,Asthma&Immunology 2005, november 4-9, Abstract Book p 84
\r8.Dong XW, ZhangSJ, Du XG, Fan X, Xie QM. Effects of XCT, a small molecule antagonist of ALPHA4 integrins on bronchoconstriction and airway inflammatory cells. Annual Scientific Meeting of the American College of Allergy,Asthma&Immunology 2005, november 4-9, Abstract Book p 84-85
\r9.Du XG, Fan X, Zhang SJ, Dong XW, Xie QM. Effects of the protien extract from Bortlatella pertussis on airway hyperresponsiveness and inflammation in sensitized mice. Annual Scientific Meeting of the American College of Allergy,Asthma&Immunology 2005, november 4-9, Abstract Book p 116
\r三、成果奖励：
\r1.《卡介苗和微卡对哮喘预防和治疗作用的系列实验研究》, 浙江省科技进步二等奖, 2005, 2\/7(本人排名\/总人数) 2.《药源性疾病基础与临床》，浙江省教育厅科技进步三等奖，2000，5\/5(本人排名\/总人数)
\r
\r

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呼吸药理学，抗炎免疫药理学
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2008-01-09 13:25:40
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selfintroduction
姓名：谢强敏
\r性别：男
\r出生地：杭州
\r所属学科：药理学
\r现任职务：国家食品药品监督管理局浙江呼吸药物研究实验室副主任
\r联系方式：
\r电话：**，**
\rE-mail：xieqm@zju.edu.cn
\r学术团体、专业杂志编委和审稿：
\r中国药理学会抗炎免疫药理专业委员会理事
\r中国药理学会制药工业药理专业委员会理事
\r浙江省生理科学专业委员会常务理事
\r浙江省药理学专业委员会理事
\r世界临床药物杂志编委
\rActa Pharmacol Sin.审稿
\rEur J Pharmacol审稿
\rJ Pharm Pharmacol审稿
\rTrends in Pharmacol审稿
\r学科专长和研究方向: 呼吸药理学，免疫药理学，新药研究
\r主持和参与的课题：
\r1.国家自然科学基金项目（2008.01—2010.12）：Rho GTPase Rac作为治疗COPD新靶点的研究
\r2.国家自然科学基金项目（2007.01—2009.12）：5-酯氧酶代谢物对哮喘的神经内分泌免疫调节作用
\r3.浙江省科技计划重点项目（2006.03—2008.12）：甘草黄酮的开发与研究
\r4.浙江省科技计划重点项目（2007.05—2009.12）：虫草头孢菌粉抗心律失常的有效成分及其作用机制研究
\r5.浙江省自然科学基金重点项目 (2005.01—2007.12)：磷酸二酯酶-4在肺部炎症疾病的作用
\r一、著作（主编1部，副主编1部，参编7部）
\r1.主编 《药理学前沿－哮喘和COPD的新概念及新药》, 专著, 2003.8, 科学出版社
\r2.第二副主编《生理科学实验教程》, 精品课程教材, 2004.8, 浙江大学出版社
\r3.参编《免疫药理学新论》, 专著, 2004.5, 人民卫生出版社
\r4.参编《抗衰老药理学新论》,专著, 2004.5, 人民卫生出版社
\r5.参编《呼吸药理学新论》,专著, 2004.5, 人民卫生出版社
\r6.参编《药理实验方法学》第三版，专著, 2004.5, 人民卫生出版社
\r7.参编《药理学和药物治疗学全书》，编著，2000，人民卫生出版社
\r8.参编《中药药理与临床》，编著，2000，人民卫生出版社
\r9.参编《呼吸药理学与治疗学》，专著, 1999, 人民卫生出版社
\r10.参编《临床药理学》，2007，人民卫生出版社
\r二、主要论文
\r1.Wu X, Zeng LH, Taniguchi T, Xie QM（通讯作者）. Activation of PKA and phosphorylation of sodium-dependent vitamin C transporter 2 by prostaglandin E2 promote osteoblast-like differentiation in MC3T3-E1 cells. Cell Death Differ. 2007;14(10):1792-1801.(IF=7.463)
\r2.Deng YM, Xie QM（通讯作者）, Zhang SJ et al. Anti-astnmatic eeffects of Perilla Seed oil in the guinea pig in vitro and in vivo. Planta Med 2007; 73(1):53-58. IF=1.746
\r3.Deng YM, Xie QM（通讯作者）, Tang HF, Sun JG, Deng JF, Chen JQ, Yang SY. Effects of ciclamilast, a new PDE 4 inhibitor, on airway hyperresponsiveness, PDE4D expression and airway inflammation in a murine model of asthma. Eur J Pharmacol. 2006 Oct 10;547(1-3):125-35. IF=2,522
\r4.Sun JG, Deng YM, Wu X, Tang HF, Deng JF, Chen JQ, Yang SY, Xie QM（通讯作者）.Inhibition of phosphodiesterase activity, airway inflammation and hyperresponsiveness by PDE4 inhibitor and glucocorticoid in a murine model of allergic asthma. Life Sci. 2006 Oct 26;79(22):2077-2085. IF=2.389
\r5.Xie QM（通讯作者）, Deng JF, Deng YM, Shao CS, Zhang H, Ke CK. Effects of cryptoporus polysaccharide on rat allergic rhinitis associated with inhibiting eotaxin mRNA expression. J Ethnopharmacol. 2006 Oct 11;107(3):424-30. IF=1.625
\r6.Tang HF, Chen JQ, Xie QM, Zheng XY, Zhu YL, Adcock I, Wang X.The role of PDE4 in pulmonary inflammation and goblet cell hyperplasia in allergic rats. Biochim Biophys Acta. 2006 May;1762(5):525-32. IF=3.297
\r7.Zhou HL, Deng YM, Xie QM（通讯作者）. The modulatory effects of the volatile oil of ginger on the cellular immune response in vitro and in vivo in mice. J Ethnopharmacol. 2006 Apr 21;105(1-2):301-5.. IF=1.625
\r8.Xu XL, Zhou JY, Yang QH,Fang LB, Xie QM, Shen YL. An in vitro rat diaphragmatic fatigue model induced by combined hypoxic and hypercapnic acidosis and the effect of salmeterol. Pharmacol Res 2006 Feb 53 (2): 171-176 IF=2.421
\r9.Deng YM, Xie QM（通讯作者）, Zhang SJ, Chen JQ, Yang QH, Bian RL. Changes of 5-lipoxygenase pathway and proinflammatory mediators in cerebral cortex and lung tissue of sensitized rats. Acta Pharmacol Sin. 2005 Mar;26(3):353-8. IF=1.397
\r10.Chen JC, Chen JQ, Xie QM, Zhu YL. Selective inhibition of purified human phosphodiesterase 4A expressed in yeast cell GL62 by ciclamilast, piclamilast, and rolipram.Acta Pharmacol Sin. 2004 Sep;25(9):1171-5. IF=1.397
\r11.Zhao XY, Xie QM（通讯作者）, Chen JQ, Ke CK.Inhibitory effects of cryptoporus polysaccharide on airway constriction,eosinophil release, and chemotaxis in guinea pigs. Acta Pharmacol Sin. 2004 Apr;25(4):503-7. IF=1.397
\r12.Deng YM, Xie QM（通讯作者）, Chen JQ, Bian RL.Coincidental increase of leukotriene B4 between cerebral cortex and lung tissue of sensitized rats. Acta Pharmacol Sin. 2003 Oct;24(10):1039-44. IF=1.397
\r13.Zhou J, Kang ZM, Xie QM, Liu C, Lou SJ, Chen YZ, Jiang CL. Rapid nongenomic effects of glucocorticoids on allergic asthma reaction in the guinea pig. J Endocrinol. 2003 Apr;177(1):R1-4. IF=3.072
\r14.Xie QM（通讯作者）, Chen JQ, Shen WH, Yang QH, Bian RL.Comparison of bronchodilating and antiinflammatory activities of oral formoterol and its (R,R)-enantiomers. Acta Pharmacol Sin. 2003 Mar;24(3):277-82. IF=1.397
\r15.Xie QM , Chen Ying, Wu Xi-mei, Chen Ji-qiang, Bian Ru-lian. Mechanism of the Effect of Santengdingtong Recipeon Monosodium Urate Crystal-Induced Rabbit Arthritis. Chinese Journal of Integrated Medicine，2003；9（2）：128-131
\r16.Xie QM（通讯作者）, Tang HF, Chen JQ, Bian RL.Pharmacological actions of tetrandrine in inflammatory pulmonary diseases. Acta Pharmacol Sin. 2002 Dec;23(12):1107-13. Review. IF=1.397
\r17.Xie QM（通讯作者）, Chen JQ, Shen WH, Bian RL.Correlative changes of interferon-gamma and interleukin-4 between cortical layer and pulmonary airway of sensitized rats. Acta Pharmacol Sin. 2002 Mar;23(3):248-52. IF=1.397
\r18.Xie QM（通讯作者）, Chen JQ, Shen WH, Yang QH, Bian RL. Effects of cyclosporin A by aerosol on airway hyperresponsiveness and inflammation in guinea pigs. Acta Pharmacol Sin. 2002 Mar;23(3):243-7. IF=1.397
\r19.Xie QM（通讯作者）, Zeng LH, Zheng YX, Lu YB, Yang QH. Bronchodilating effects of bambuterol on bronchoconstriction in guinea pigs.Acta Pharmacol Sin.1999 Jul;20(7):651-4. IF=1.397
\r近2年参加重要国际学术会议大会发言和论文摘要
\r1.Xie QM, Deng YM, Chen JQ. The neuro-endocrine-immumo regulation of 5-lipoxygenase in the asthmatic model of rats. XVth World Congress of Pharmacology: Meeting Abstract P 340059, July 2-7, 2006
\r2.Tang HF, Chen JQ, Xie QM. Upregulation of PDE4 activity and expression in lung of asthmatic rats. XVth World Congress of Pharmacology: Meeting Abstract P 340053
\r3.Deng YM, Xie QM, Chen JQ, Zhang SJ, Yao HY, Zhang H. Anti-asthma effects of perilla seed oil in the guinea pig in vivo and vitro. XVth World Congress of Pharmacology: Meeting Abstract P 340065, July 2-7, 2006
\r4.Li ZG, Xie QM, Yin ZQ, Tang HF, Chen JQ. Inhibitory effects of local anesthetis on contractions of pregnant rat myometrium. XVth World Congress of Pharmacology: Meeting Abstract P 340076, July 2-7, 2006
\r5.Chen JQ, Xia Q, Xie QM, Wei EQ, Fu LQ. Pharmacology in the integrated course “Basic Medical Sciences” in Zhejiang University of School of Medicine. XVth World Congress of Pharmacology: Meeting Abstract P 410007, July 2-7, 2006
\r6.Xie QM, Hu HM, Zhu YL, Zhang SJ, Chen JQ. Desensitization effect of sublingul immunotherapy on the dust mite sensitized rats. Abstracts presented at concurrent aessions. Annual Scientific Meeting of the American College of Allergy,Asthma&Immunology 2005, november 4-9, Abstract Book p 50.
\r7.Xie QM, Deng YM, Sun JG, Tang HF, Deng JF, Chen JQ. Effects of Ciclamilast, a new PDE4 inhibitor, on upregulation of PDE4, airway mucus hypersecretion and airway hyperresponsiveness in mouse asthmatis model. Annual Scientific Meeting of the American College of Allergy,Asthma&Immunology 2005, november 4-9, Abstract Book p 84
\r8.Dong XW, ZhangSJ, Du XG, Fan X, Xie QM. Effects of XCT, a small molecule antagonist of ALPHA4 integrins on bronchoconstriction and airway inflammatory cells. Annual Scientific Meeting of the American College of Allergy,Asthma&Immunology 2005, november 4-9, Abstract Book p 84-85
\r9.Du XG, Fan X, Zhang SJ, Dong XW, Xie QM. Effects of the protien extract from Bortlatella pertussis on airway hyperresponsiveness and inflammation in sensitized mice. Annual Scientific Meeting of the American College of Allergy,Asthma&Immunology 2005, november 4-9, Abstract Book p 116
\r三、成果奖励：
\r1.《卡介苗和微卡对哮喘预防和治疗作用的系列实验研究》, 浙江省科技进步二等奖, 2005, 2\/7(本人排名\/总人数) 2.《药源性疾病基础与临床》，浙江省教育厅科技进步三等奖，2000，5\/5(本人排名\/总人数)
\r
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xieqm@zju.edu.cn
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2021-01-23 18:40:45
content
姓名：谢强敏
\r性别：男
\r出生地：杭州
\r所属学科：药理学
\r现任职务：国家食品药品监督管理局浙江呼吸药物研究实验室副主任
\r联系方式：
\r电话：**，**
\rE-mail：xieqm@zju.edu.cn
\r学术团体、专业杂志编委和审稿：
\r中国药理学会抗炎免疫药理专业委员会理事
\r中国药理学会制药工业药理专业委员会理事
\r浙江省生理科学专业委员会常务理事
\r浙江省药理学专业委员会理事
\r世界临床药物杂志编委
\rActa Pharmacol Sin.审稿
\rEur J Pharmacol审稿
\rJ Pharm Pharmacol审稿
\rTrends in Pharmacol审稿
\r学科专长和研究方向: 呼吸药理学，免疫药理学，新药研究
\r主持和参与的课题：
\r1.国家自然科学基金项目（2008.01—2010.12）：Rho GTPase Rac作为治疗COPD新靶点的研究
\r2.国家自然科学基金项目（2007.01—2009.12）：5-酯氧酶代谢物对哮喘的神经内分泌免疫调节作用
\r3.浙江省科技计划重点项目（2006.03—2008.12）：甘草黄酮的开发与研究
\r4.浙江省科技计划重点项目（2007.05—2009.12）：虫草头孢菌粉抗心律失常的有效成分及其作用机制研究
\r5.浙江省自然科学基金重点项目 (2005.01—2007.12)：磷酸二酯酶-4在肺部炎症疾病的作用
\r一、著作（主编1部，副主编1部，参编7部）
\r1.主编 《药理学前沿－哮喘和COPD的新概念及新药》, 专著, 2003.8, 科学出版社
\r2.第二副主编《生理科学实验教程》, 精品课程教材, 2004.8, 浙江大学出版社
\r3.参编《免疫药理学新论》, 专著, 2004.5, 人民卫生出版社
\r4.参编《抗衰老药理学新论》,专著, 2004.5, 人民卫生出版社
\r5.参编《呼吸药理学新论》,专著, 2004.5, 人民卫生出版社
\r6.参编《药理实验方法学》第三版，专著, 2004.5, 人民卫生出版社
\r7.参编《药理学和药物治疗学全书》，编著，2000，人民卫生出版社
\r8.参编《中药药理与临床》，编著，2000，人民卫生出版社
\r9.参编《呼吸药理学与治疗学》，专著, 1999, 人民卫生出版社
\r10.参编《临床药理学》，2007，人民卫生出版社
\r二、主要论文
\r1.Wu X, Zeng LH, Taniguchi T, Xie QM（通讯作者）. Activation of PKA and phosphorylation of sodium-dependent vitamin C transporter 2 by prostaglandin E2 promote osteoblast-like differentiation in MC3T3-E1 cells. Cell Death Differ. 2007;14(10):1792-1801.(IF=7.463)
\r2.Deng YM, Xie QM（通讯作者）, Zhang SJ et al. Anti-astnmatic eeffects of Perilla Seed oil in the guinea pig in vitro and in vivo. Planta Med 2007; 73(1):53-58. IF=1.746
\r3.Deng YM, Xie QM（通讯作者）, Tang HF, Sun JG, Deng JF, Chen JQ, Yang SY. Effects of ciclamilast, a new PDE 4 inhibitor, on airway hyperresponsiveness, PDE4D expression and airway inflammation in a murine model of asthma. Eur J Pharmacol. 2006 Oct 10;547(1-3):125-35. IF=2,522
\r4.Sun JG, Deng YM, Wu X, Tang HF, Deng JF, Chen JQ, Yang SY, Xie QM（通讯作者）.Inhibition of phosphodiesterase activity, airway inflammation and hyperresponsiveness by PDE4 inhibitor and glucocorticoid in a murine model of allergic asthma. Life Sci. 2006 Oct 26;79(22):2077-2085. IF=2.389
\r5.Xie QM（通讯作者）, Deng JF, Deng YM, Shao CS, Zhang H, Ke CK. Effects of cryptoporus polysaccharide on rat allergic rhinitis associated with inhibiting eotaxin mRNA expression. J Ethnopharmacol. 2006 Oct 11;107(3):424-30. IF=1.625
\r6.Tang HF, Chen JQ, Xie QM, Zheng XY, Zhu YL, Adcock I, Wang X.The role of PDE4 in pulmonary inflammation and goblet cell hyperplasia in allergic rats. Biochim Biophys Acta. 2006 May;1762(5):525-32. IF=3.297
\r7.Zhou HL, Deng YM, Xie QM（通讯作者）. The modulatory effects of the volatile oil of ginger on the cellular immune response in vitro and in vivo in mice. J Ethnopharmacol. 2006 Apr 21;105(1-2):301-5.. IF=1.625
\r8.Xu XL, Zhou JY, Yang QH,Fang LB, Xie QM, Shen YL. An in vitro rat diaphragmatic fatigue model induced by combined hypoxic and hypercapnic acidosis and the effect of salmeterol. Pharmacol Res 2006 Feb 53 (2): 171-176 IF=2.421
\r9.Deng YM, Xie QM（通讯作者）, Zhang SJ, Chen JQ, Yang QH, Bian RL. Changes of 5-lipoxygenase pathway and proinflammatory mediators in cerebral cortex and lung tissue of sensitized rats. Acta Pharmacol Sin. 2005 Mar;26(3):353-8. IF=1.397
\r10.Chen JC, Chen JQ, Xie QM, Zhu YL. Selective inhibition of purified human phosphodiesterase 4A expressed in yeast cell GL62 by ciclamilast, piclamilast, and rolipram.Acta Pharmacol Sin. 2004 Sep;25(9):1171-5. IF=1.397
\r11.Zhao XY, Xie QM（通讯作者）, Chen JQ, Ke CK.Inhibitory effects of cryptoporus polysaccharide on airway constriction,eosinophil release, and chemotaxis in guinea pigs. Acta Pharmacol Sin. 2004 Apr;25(4):503-7. IF=1.397
\r12.Deng YM, Xie QM（通讯作者）, Chen JQ, Bian RL.Coincidental increase of leukotriene B4 between cerebral cortex and lung tissue of sensitized rats. Acta Pharmacol Sin. 2003 Oct;24(10):1039-44. IF=1.397
\r13.Zhou J, Kang ZM, Xie QM, Liu C, Lou SJ, Chen YZ, Jiang CL. Rapid nongenomic effects of glucocorticoids on allergic asthma reaction in the guinea pig. J Endocrinol. 2003 Apr;177(1):R1-4. IF=3.072
\r14.Xie QM（通讯作者）, Chen JQ, Shen WH, Yang QH, Bian RL.Comparison of bronchodilating and antiinflammatory activities of oral formoterol and its (R,R)-enantiomers. Acta Pharmacol Sin. 2003 Mar;24(3):277-82. IF=1.397
\r15.Xie QM , Chen Ying, Wu Xi-mei, Chen Ji-qiang, Bian Ru-lian. Mechanism of the Effect of Santengdingtong Recipeon Monosodium Urate Crystal-Induced Rabbit Arthritis. Chinese Journal of Integrated Medicine，2003；9（2）：128-131
\r16.Xie QM（通讯作者）, Tang HF, Chen JQ, Bian RL.Pharmacological actions of tetrandrine in inflammatory pulmonary diseases. Acta Pharmacol Sin. 2002 Dec;23(12):1107-13. Review. IF=1.397
\r17.Xie QM（通讯作者）, Chen JQ, Shen WH, Bian RL.Correlative changes of interferon-gamma and interleukin-4 between cortical layer and pulmonary airway of sensitized rats. Acta Pharmacol Sin. 2002 Mar;23(3):248-52. IF=1.397
\r18.Xie QM（通讯作者）, Chen JQ, Shen WH, Yang QH, Bian RL. Effects of cyclosporin A by aerosol on airway hyperresponsiveness and inflammation in guinea pigs. Acta Pharmacol Sin. 2002 Mar;23(3):243-7. IF=1.397
\r19.Xie QM（通讯作者）, Zeng LH, Zheng YX, Lu YB, Yang QH. Bronchodilating effects of bambuterol on bronchoconstriction in guinea pigs.Acta Pharmacol Sin.1999 Jul;20(7):651-4. IF=1.397
\r近2年参加重要国际学术会议大会发言和论文摘要
\r1.Xie QM, Deng YM, Chen JQ. The neuro-endocrine-immumo regulation of 5-lipoxygenase in the asthmatic model of rats. XVth World Congress of Pharmacology: Meeting Abstract P 340059, July 2-7, 2006
\r2.Tang HF, Chen JQ, Xie QM. Upregulation of PDE4 activity and expression in lung of asthmatic rats. XVth World Congress of Pharmacology: Meeting Abstract P 340053
\r3.Deng YM, Xie QM, Chen JQ, Zhang SJ, Yao HY, Zhang H. Anti-asthma effects of perilla seed oil in the guinea pig in vivo and vitro. XVth World Congress of Pharmacology: Meeting Abstract P 340065, July 2-7, 2006
\r4.Li ZG, Xie QM, Yin ZQ, Tang HF, Chen JQ. Inhibitory effects of local anesthetis on contractions of pregnant rat myometrium. XVth World Congress of Pharmacology: Meeting Abstract P 340076, July 2-7, 2006
\r5.Chen JQ, Xia Q, Xie QM, Wei EQ, Fu LQ. Pharmacology in the integrated course “Basic Medical Sciences” in Zhejiang University of School of Medicine. XVth World Congress of Pharmacology: Meeting Abstract P 410007, July 2-7, 2006
\r6.Xie QM, Hu HM, Zhu YL, Zhang SJ, Chen JQ. Desensitization effect of sublingul immunotherapy on the dust mite sensitized rats. Abstracts presented at concurrent aessions. Annual Scientific Meeting of the American College of Allergy,Asthma&Immunology 2005, november 4-9, Abstract Book p 50.
\r7.Xie QM, Deng YM, Sun JG, Tang HF, Deng JF, Chen JQ. Effects of Ciclamilast, a new PDE4 inhibitor, on upregulation of PDE4, airway mucus hypersecretion and airway hyperresponsiveness in mouse asthmatis model. Annual Scientific Meeting of the American College of Allergy,Asthma&Immunology 2005, november 4-9, Abstract Book p 84
\r8.Dong XW, ZhangSJ, Du XG, Fan X, Xie QM. Effects of XCT, a small molecule antagonist of ALPHA4 integrins on bronchoconstriction and airway inflammatory cells. Annual Scientific Meeting of the American College of Allergy,Asthma&Immunology 2005, november 4-9, Abstract Book p 84-85
\r9.Du XG, Fan X, Zhang SJ, Dong XW, Xie QM. Effects of the protien extract from Bortlatella pertussis on airway hyperresponsiveness and inflammation in sensitized mice. Annual Scientific Meeting of the American College of Allergy,Asthma&Immunology 2005, november 4-9, Abstract Book p 116
\r三、成果奖励：
\r1.《卡介苗和微卡对哮喘预防和治疗作用的系列实验研究》, 浙江省科技进步二等奖, 2005, 2\/7(本人排名\/总人数) 2.《药源性疾病基础与临床》，浙江省教育厅科技进步三等奖，2000，5\/5(本人排名\/总人数)
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