寿惠霞

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欢迎来到寿惠霞教授实验室！

寿惠霞，1981年进入浙江农业大学农学系学习，1988年获植物遗传与育种学硕士学位；1998年赴美留学，学习植物分子生物学与转基因技术，2003博士毕业于美国爱荷华州立大学植物转基因研究中心。2004年回国任浙江大学生命科学学院教授、博士生导师，现任生科院生物技术系主任，浙江大学-爱丁堡大学工程生物中心主任。2013年入选浙江大学“求是特聘****”。
多年来从事植物转基因和植物基因组研究，已在植物功能基因克隆、植物转基因技术体系研究、植物抗逆转基因及其分子机理研究等方面取得多项研究成果。在National Science Review、PNAS、Plant Journal、 Plant Physiology、 Molecular Plant、CellResearch 等杂志发表发表研究论文60余篇。实验室在植物功能基因研究方向承担国家重点基础研究计划项目、国家转基因专项、国家基金项目、国际Harvestplus项目等多项科研项目。
主要研究方向包括：水稻、大豆磷铁吸收代谢关键基因的克隆及功能研究；大豆功能基因研究；抗除草剂大豆新种质创制研究。
实验室现有副教授（副研究员），博士后、博士、硕士研究生18名，技术员2名；实验室师生关系融洽，学习气氛浓郁。

******************************************************************
近5年发表的论文:
1. Wang SD, Liu SL, Wang J, Yokosho K, Zhou B, Yu YC, Liu Z, Frommer WB, Ma JF, Chen LQ*, Guan Y*, Shou H*, Tian Z*. Simultaneous changes in seed size, oil content, and protein content driven by selection of SWEET homologues during soybean domestication. Natl Sci Rev. nwaa110, https:\/\/doi.org\/10.1093\/nsr\/nwaa110
2. Wang SD, Li L, Ying YH, Wang J, Shao JF, Yamaji N, Whelan J, Ma JF, Shou HX*. 2020. A transcription factor OsbHLH156 regulates Strategy II iron acquisition through localising IRO2 to the nucleus in rice. New Phytol. 225: 1247-1260
3. Borges MB, Ng S, Berkowitz O, Clercq ID, Mao CZ, Shou HX, Whelan J, Jost R. 2019. At-SPX4 regulates intracellular P status in shoots. Plant Physiol. pp.00594.2018
4. Wang SD, Yokosho K, Guo RZ, Whelan J, Ruan YL, Ma JF, Shou HX*. 2019. The Soybean Sugar Transporter GmSWEET15 Mediates Sucrose Export from Endosperm to Early Embryo. Plant Physiol. 180 (4) 2133-2141
5. Li L, Ye L, Kong Q, Shou HX*. 2019. A vacuolar membrane ferric-chelate reductase, OsFRO1 alleviates Fe toxicity in rice (Oryza sativa L.). Front Plant Sci. 10: doi: 10.3389\/fpls.2019.00700
6. Li L,Gao WW, Peng Q, Zhou B, Kong QH, Ying YH, Shou HX*. 2018. Two soybean bHLH factors regulate response to iron deficiency. J Integ Plant Biol. 20(7) :608-622.
7. Lu L,Dong C,Liu R,Zhou B,Wang C,Shou HX*. 2018. Roles of soybean plasma membrane intrinsic protein GmPIP2;9 in drought tolerance and seed development. Front Plant Sci. 9:530. doi: 10.3389\/fpls.2018.00530.
8. Gao WW, Lu LH, Qiu WM, Wang C, Shou HX*. 2017. OsPAP26 encodes a major purple acid phosphatase and regulates phosphate remobilization in rice. Plant Cell & Physiol. 58 (5), 885-892
9. Li S, Ying YH, Secco D, Wang C, Narsai R, Whelan J, Shou HX*. 2017. Molecular interaction between PHO2 and GIGANTEA reveals a new crosstalk between flowering time and phosphate homeostasis in Oryza sativa. Plant Cell & Envir. 40(8):1487-1499.
10. Yue WH, Ying YH, Wang C, Zhao Y, Dong CH, Whelan J, Shou HX*. 2017. OsNLA1, a RING-type ubiquitin ligase, maintains phosphate homeostasis in Oryza sativa via degradation of phosphate transporters. Plant J. 90(6):1040-1051
11. Ying YH, Yue WH, Wang SD, Li S, Wang M, Zhao Y, Wang C, Mao CZ, Whelan J, Shou HX*. 2017. Two h-type thioredoxins interact with the PHO2ubiquitin-conjugating E2 enzyme to fine-tune phosphate homeostasis in rice. Plant Physiol. 173: 812–824
12. Du J, Wang SD, He CM, Zhou B, Ruan YL, Shou HX*. 2017. Identification of regulatory networks and hub genes controlling soybean seed set and size using RNA-Seq. J Exp Bot. 68(8):1955-1972.
13. Lu GH, Hua XM, Cheng J, Zhu YL, Wang GH, Pang YJ, Yang RW, Zhang L , Shou, HX , Wang XM, Qi JL, Yang, YH. 2018. Impact of Glyphosate on the Rhizosphere Microbial Communities of An EPSPS-Transgenic Soybean Line ZUTS31 by Metagenome Sequencing. Current Genomics. 19:36-49
14. Lu LH, Qiu WM, Gao WW, Tyerman S, Wang C*, Shou HX*. 2016. OsPAP10c, a novel secreted acid phosphatase in rice, plays an important role in utilization of external organic phosphorus. Plant Cell & Envir. 39:2249-2259
15. Li S, Yue WH, Wang M, Qiu WM, Zhou L, Shou HX*. 2016. Mutation of OsGIGANTEA leads to enhanced tolerance to polyethylene glycol-generated osmotic stress in rice. Front. Plant Sci.7:465
16. Foyer CH, Lam HM, Nguyen HT, Siddique KHM, Varshney RK, Colmer TD, Cowling W, Bramley H, Mori TA, Hodgson JM, Cooper JW, Miller AJ, Kunert K, Vorster J, Cullis C, Ozga JA, Wahlqvist ML, Liang Y, Shou HX, Shi K, Yu JQ, Fodor N, Kaiser BN, Wong FL, Valliyodan B, Considine MJ. 2016. Neglecting legumes has compromised human health and sustainable food production. Nature-Plant, 2:16112
17. Wang C, Yue WH, Ying YH, Wang SD, Secco D, Liu Y, Whelan J, Tyerman S, Shou HX*. 2015. Rice SPX-Major Facility Superfamily3, a vacuolar phosphate efflux transporter, is involved in maintaining phosphate homeostasis in rice. Plant Physiol. 169: 2822-2831.
18. Ye LX, Li L, Wang L, Wang SD, Li S, Du J, Zhang SQ, Shou HX*. 2015. MPK3\/MPK6 are involved in iron deficiency-induced ethylene production in Arabidopsis. Front. Plant Sci. 6: 953
19. Secco D, Wang C, Shou HX, Schultz MD，Chiarenza S, Nussaume L, Ecker J, Whelan J, Lister R. 2015. Stress induced gene expression drives transient DNA methylation changes at adjacent repetitive elements. eLife 2015;4:e09343.
20. Nawaz Z, Kakar KU, Li XB, Li S, Zhang B, Shou HX, Shu QY. Genome-wide association mapping of quantitative trait loci (QTLs) for contents of eight elements in brown rice. 2015. J Agri Food Chem. 63, 8008?8016


诚邀有志于植物分子生物学、生理学基础研究及生物技术应用研究的博士后研究人员、博士和硕士研究生加入研究团队。



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植物分子生物学、植物生理学、植物营养遗传学、植物生物技术。\r《分子生物学》、《基因组学》教学
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selfintroduction
\r \r \r \r
\r 欢迎来到寿惠霞教授实验室！\r

\r 本人1981年进入浙江农业大学农学系学习，1988年获植物遗传与育种学硕士学位；1998年赴美留学，学习植物分子生物学与转基因技术，2003博士毕业于美国爱荷华州立大学植物转基因研究中心。2004年回国任浙江大学生命科学学院教授、博士生导师、生物技术系主任，植物研究所副所长。2013年入选浙江大学“求是特聘****”。
\r 多年来从事植物转基因和植物基因组研究，已在植物功能基因克隆、植物转基因技术体系研究、植物抗逆转基因及其分子机理研究等方面取得多项研究成果。在PNAS、Plant Journal、 Plant Physiology、 CellResearch 等杂志发表发表研究论文40余篇。实验室在植物功能基因研究方向承担国家重点基础研究计划项目、国家转基因专项、国家基金项目、国际Harvestplus项目等多项科研项目。
\r 主要研究方向包括：水稻、大豆磷铁吸收代谢关键基因的克隆及功能研究；大豆功能基因研究；抗除草剂大豆新种质创制研究。
\r 实验室现有副教授（副研究员），博士后、博士、硕士研究生12名，技术员1名；实验室师生关系融洽，学习气氛浓郁。
\r ******************************************************************
\r 近5年发表的论文:
\r
\r 1. Ying YH, Yue WH, Wang SD, Li S, Wang M, Zhao Y, Wang C, Mao CZ, Whelan J, Shou HX*. 2016. Two h-type thioredoxins interact with Oryza sativa PHO2 to fine-tune phosphate homeostasis. Plant Physiol. doi: http:\/\/dx.doi.org\/10.1104\/pp.16.01639\r 2. Duan J, Wang SD, He Cuman, Zhou B, Ruan YL, Shou HX*. 2016. Identification of regulatory networks and hub genes controlling soybean seed set and size using RNA-Seq. J. Exp. Bot. 2016doi:10.1093\/jxb\/erw425
\r 3. Lu LH, Qiu WM, Gao WW, Tyerman S, Wang C*, Shou HX*. 2016. OsPAP10c, a novel secreted acid phosphatase in rice, plays an important role in utilization of external organic phosphorus. Plant Cell Envir. 39:2249-2259
\r 4. Li S, Yue WH, Wang M, Qiu WM, Zhou L, Shou HX*. 2016. Mutation of OsGIGANTEA leads to enhanced tolerance to polyethylene glycol-generated osmotic stress in rice. Front. Plant Sci.,http:\/\/dx.doi.org\/10.3389\/fpls. 2016.00465.
\r 5. Wang C, Yue WH, Ying YH, Wang SD, Secco D, Liu Y, Whelan J, Tyerman S, Shou HX*. 2015. Rice SPX-Major Facility Superfamily3, a vacuolar phosphate efflux transporter, is involved in maintaining phosphate homeostasis in rice. Plant Physiol. 169: 2822-2831.
\r 6. Ye LX, Li L, Wang L, Wang SD, Li S, Du J, Zhang SQ, Shou HX*. 2015. MPK3\/MPK6 are involved in iron deficiency-induced ethylene production in Arabidopsis. Front. Plant Sci.,http:\/\/dx.doi.org\/10.3389\/fpls.2015.00953
\r 7. Secco D, Wang C, Shou HX, Schultz MD，Chiarenza S, Nussaume L, Ecker J, Whelan J, Lister R. 2015. Stress induced gene expression drives transient DNA methylation changes at adjacent repetitive elements. eLife 2015;4:e09343.
\r 8. Nawaz Z, Kakar KU, Li XB, Li S, Zhang B, Shou HX, Shu QY. Genome-wide association mapping of quantitative trait loci (QTLs) for contents of eight elements in brown rice. 2015. J Agri Food Chem. 63, 8008−8016
\r 9. Zhou L, Wang C, Liu RF, Han Q, Rebecca VK, Juan D, Tyerman S, Shou HX*. 2014. Constitutive overexpression of soybean plasma membrane intrinsic protein GmPIP1;6 confers salt tolerance. BMC Plant Biol. 14:181doi:10.1186\/1471-2229-14-181
\r 10. Zhou L, He HL, Liu RF, Han Q, Liu B, Shou HX*. 2014. Overexpression of GmAKT2 potassium channel enhances resistance to soybean mosaic virus. BMC Plant Biol14:154 doi:10.1186\/1471-2229-14-154
\r 11. Wang C, Li S, Ng S, Zhang BC, Zhou YH, Whelan J, Wu P, Shou HX. 2014. Mutation in xyloglucan 6-xylosytransferase results in abnormal root hair development in Oryza sativa. J. Exp. Bot. 65:4149-4157
\r 12. Li S, Wang C, Zhou L, Shou HX, 2014. Oxygen deficit alleviates phosphate overaccumulation toxicity in OsPHR2 overexpression plants. J Plant Res 127:433-440.
\r 13. Narsai R, Devenish J, Castleden I, Narsai K, Xu L, Shou HX, Whelan J. 2013. Rice DB: an Oryza Information Portal linking annotation, subcellular location, function, expression, regulation, and evolutionary information for rice and Arabidopsis. Plant J 76: 1057–1073
\r 14. Secco D, Shou HX, Whelan J, Berkowitz O. 2014. RNA-seq analysis identifies an intricate regulatory network controlling cluster root development in white lupin. BMC Genom. 15:230 doi:10.1186\/1471-2164-15-230
\r 15. Song ZY, Tian JL, Fu WZ, Li L, Lu LH, Zhou L, Shan ZH, Tang GX, Shou HX*. 2013. Screening Chinese soybean genotypes for Agrobacterium-mediated genetic transformation suitability. J Zhejiang Univ Sci B. 14:289-198
\r 16. Wu P, Shou HX, Xu GH, Lian XM, 2013. Improvement of phosphorus efficiency in rice on the basis of understanding phosphate signaling and homeostasis. Curr Opin Plant Biol. 16: 205–212
\r 17. Secco D, Jabnoune M, Walker H, Shou HX, Wu P, Poirier Y, Whelan J, 2013. Spatio-Temporal Transcript Profiling of Rice Roots and Shoots in Response to Phosphate Starvation and Recovery. Plant Cell. 25:4285-4304.
\r 18. Wang L, Ying YH, Narsai R, Ye L, Zheng L, Tian J, Whelan J, Shou HX*. 2013. Identification of OsbHLH133 as a regulator of iron distribution between roots and shoots in Oryza sativa. Plant Cell & Envir. doi: 36:224-236
\r 19. Wang C, Huang W, Ying YH, Li S, Secco D, Tyerman S, Whelan J, Shou HX*. 2012. Functional characterization of the rice SPX-MFS family reveals a key role of OsSPX-MFS1 in controlling phosphate homeostasis in leaves. New Phytol. 196： 139–148
\r 20. Tian JL, Wang C, Zhang Q, He XW, Whelan J, Shou HX*. 2012. Overexpression of OsPAP10a, a root-associated acid phosphatase, increased extracellular organic phosphorus utilization in rice. J. Integr. Plant Biol. 54 (9): 631–639
\r 21. Secco D, Wang C, Arpat BA, Wang ZY, Poirier Y, Tyerman SD, Wu P, Shou HX, Whelan J. 2012. The emerging importance of the SPX domain-containing proteins in phosphate homeostasis. New Phyt. 193: 842–851
\r 22. Secco D, Wang C, Shou HX, Whelan J. 2012. Phosphate homeostasis in the yeast Saccharomyces cerevisiae, the key role of the SPX domain-containing proteins. FEBS Letters 586: 289-295. (IF: 3.5)
\r 23. Wu JJ, Wang C, Zheng LQ, Wang L, ChenYR, Whelan J, Shou HX* . 2011. Ethylene is involved in the regulation of iron homeostasis in rice by regulating the expression of iron-acquisition-related genes in Oryza sativa. J. Exp. Bot. 62：667-674.
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\r 诚邀有志于植物分子生物学、生理学基础研究及生物技术应用研究的博士后研究人员、博士和硕士研究生加入研究团队。
\r 2017年计划再招收硕士研究生2名、博士后2名。
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huixia@zju.edu.cn
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浙江大学紫金港校区生命科学学院402
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2021-01-24 22:42:56
content

欢迎来到寿惠霞教授实验室！

寿惠霞，1981年进入浙江农业大学农学系学习，1988年获植物遗传与育种学硕士学位；1998年赴美留学，学习植物分子生物学与转基因技术，2003博士毕业于美国爱荷华州立大学植物转基因研究中心。2004年回国任浙江大学生命科学学院教授、博士生导师，现任生科院生物技术系主任，浙江大学-爱丁堡大学工程生物中心主任。2013年入选浙江大学“求是特聘****”。
多年来从事植物转基因和植物基因组研究，已在植物功能基因克隆、植物转基因技术体系研究、植物抗逆转基因及其分子机理研究等方面取得多项研究成果。在National Science Review、PNAS、Plant Journal、 Plant Physiology、 Molecular Plant、CellResearch 等杂志发表发表研究论文60余篇。实验室在植物功能基因研究方向承担国家重点基础研究计划项目、国家转基因专项、国家基金项目、国际Harvestplus项目等多项科研项目。
主要研究方向包括：水稻、大豆磷铁吸收代谢关键基因的克隆及功能研究；大豆功能基因研究；抗除草剂大豆新种质创制研究。
实验室现有副教授（副研究员），博士后、博士、硕士研究生18名，技术员2名；实验室师生关系融洽，学习气氛浓郁。

******************************************************************
近5年发表的论文:
1. Wang SD, Liu SL, Wang J, Yokosho K, Zhou B, Yu YC, Liu Z, Frommer WB, Ma JF, Chen LQ*, Guan Y*, Shou H*, Tian Z*. Simultaneous changes in seed size, oil content, and protein content driven by selection of SWEET homologues during soybean domestication. Natl Sci Rev. nwaa110, https:\/\/doi.org\/10.1093\/nsr\/nwaa110
2. Wang SD, Li L, Ying YH, Wang J, Shao JF, Yamaji N, Whelan J, Ma JF, Shou HX*. 2020. A transcription factor OsbHLH156 regulates Strategy II iron acquisition through localising IRO2 to the nucleus in rice. New Phytol. 225: 1247-1260
3. Borges MB, Ng S, Berkowitz O, Clercq ID, Mao CZ, Shou HX, Whelan J, Jost R. 2019. At-SPX4 regulates intracellular P status in shoots. Plant Physiol. pp.00594.2018
4. Wang SD, Yokosho K, Guo RZ, Whelan J, Ruan YL, Ma JF, Shou HX*. 2019. The Soybean Sugar Transporter GmSWEET15 Mediates Sucrose Export from Endosperm to Early Embryo. Plant Physiol. 180 (4) 2133-2141
5. Li L, Ye L, Kong Q, Shou HX*. 2019. A vacuolar membrane ferric-chelate reductase, OsFRO1 alleviates Fe toxicity in rice (Oryza sativa L.). Front Plant Sci. 10: doi: 10.3389\/fpls.2019.00700
6. Li L,Gao WW, Peng Q, Zhou B, Kong QH, Ying YH, Shou HX*. 2018. Two soybean bHLH factors regulate response to iron deficiency. J Integ Plant Biol. 20(7) :608-622.
7. Lu L,Dong C,Liu R,Zhou B,Wang C,Shou HX*. 2018. Roles of soybean plasma membrane intrinsic protein GmPIP2;9 in drought tolerance and seed development. Front Plant Sci. 9:530. doi: 10.3389\/fpls.2018.00530.
8. Gao WW, Lu LH, Qiu WM, Wang C, Shou HX*. 2017. OsPAP26 encodes a major purple acid phosphatase and regulates phosphate remobilization in rice. Plant Cell & Physiol. 58 (5), 885-892
9. Li S, Ying YH, Secco D, Wang C, Narsai R, Whelan J, Shou HX*. 2017. Molecular interaction between PHO2 and GIGANTEA reveals a new crosstalk between flowering time and phosphate homeostasis in Oryza sativa. Plant Cell & Envir. 40(8):1487-1499.
10. Yue WH, Ying YH, Wang C, Zhao Y, Dong CH, Whelan J, Shou HX*. 2017. OsNLA1, a RING-type ubiquitin ligase, maintains phosphate homeostasis in Oryza sativa via degradation of phosphate transporters. Plant J. 90(6):1040-1051
11. Ying YH, Yue WH, Wang SD, Li S, Wang M, Zhao Y, Wang C, Mao CZ, Whelan J, Shou HX*. 2017. Two h-type thioredoxins interact with the PHO2ubiquitin-conjugating E2 enzyme to fine-tune phosphate homeostasis in rice. Plant Physiol. 173: 812–824
12. Du J, Wang SD, He CM, Zhou B, Ruan YL, Shou HX*. 2017. Identification of regulatory networks and hub genes controlling soybean seed set and size using RNA-Seq. J Exp Bot. 68(8):1955-1972.
13. Lu GH, Hua XM, Cheng J, Zhu YL, Wang GH, Pang YJ, Yang RW, Zhang L , Shou, HX , Wang XM, Qi JL, Yang, YH. 2018. Impact of Glyphosate on the Rhizosphere Microbial Communities of An EPSPS-Transgenic Soybean Line ZUTS31 by Metagenome Sequencing. Current Genomics. 19:36-49
14. Lu LH, Qiu WM, Gao WW, Tyerman S, Wang C*, Shou HX*. 2016. OsPAP10c, a novel secreted acid phosphatase in rice, plays an important role in utilization of external organic phosphorus. Plant Cell & Envir. 39:2249-2259
15. Li S, Yue WH, Wang M, Qiu WM, Zhou L, Shou HX*. 2016. Mutation of OsGIGANTEA leads to enhanced tolerance to polyethylene glycol-generated osmotic stress in rice. Front. Plant Sci.7:465
16. Foyer CH, Lam HM, Nguyen HT, Siddique KHM, Varshney RK, Colmer TD, Cowling W, Bramley H, Mori TA, Hodgson JM, Cooper JW, Miller AJ, Kunert K, Vorster J, Cullis C, Ozga JA, Wahlqvist ML, Liang Y, Shou HX, Shi K, Yu JQ, Fodor N, Kaiser BN, Wong FL, Valliyodan B, Considine MJ. 2016. Neglecting legumes has compromised human health and sustainable food production. Nature-Plant, 2:16112
17. Wang C, Yue WH, Ying YH, Wang SD, Secco D, Liu Y, Whelan J, Tyerman S, Shou HX*. 2015. Rice SPX-Major Facility Superfamily3, a vacuolar phosphate efflux transporter, is involved in maintaining phosphate homeostasis in rice. Plant Physiol. 169: 2822-2831.
18. Ye LX, Li L, Wang L, Wang SD, Li S, Du J, Zhang SQ, Shou HX*. 2015. MPK3\/MPK6 are involved in iron deficiency-induced ethylene production in Arabidopsis. Front. Plant Sci. 6: 953
19. Secco D, Wang C, Shou HX, Schultz MD，Chiarenza S, Nussaume L, Ecker J, Whelan J, Lister R. 2015. Stress induced gene expression drives transient DNA methylation changes at adjacent repetitive elements. eLife 2015;4:e09343.
20. Nawaz Z, Kakar KU, Li XB, Li S, Zhang B, Shou HX, Shu QY. Genome-wide association mapping of quantitative trait loci (QTLs) for contents of eight elements in brown rice. 2015. J Agri Food Chem. 63, 8008?8016


诚邀有志于植物分子生物学、生理学基础研究及生物技术应用研究的博士后研究人员、博士和硕士研究生加入研究团队。



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