连佳长 (Lian, Jiazhang) - SMEL
合成生物学与代谢工程实验室 (Synthetic Metabolic Engineering Laboratory, SMEL)
summary
连佳长博士，生物质化工教育部重点实验室副主任，化学工程与生物工程学院研究员，博士生导师，入选国家级青年人才计划和浙江大学“****”，浙江省****基金获得者。主要从事基于合成生物学原理和基因组编辑技术的人工细胞工厂创建研究。共发表论文40余篇，包括Nature Communications,Metabolic Engineering, ACS Synthetic Biology, Biotechnology and Bioengineering, Applied Microbiology and Biotechnology等。受邀担任BMC Biotechnology Associate Editor、《合成生物学》编委、Frontiers in Biotechnology and Bioengineeringrs in Biotechnology and Bioengineering客座编辑以及Nature Chemical Biology,Metabolic Engineering, Applied Microbiology and Biotechnology, Biotechnology for Biofuels, Microbial Cell Factories, Journal of Industrial Microbiology and Biotechnology, Enzyme and Microbial Technology, Biochemical Engineering Journal, BMC Biotechnology等期刊审稿人。

教育背景
2003-2007，浙江大学，生物工程，学士
2007-2010，浙江大学，生物化工，硕士
2010-2015，伊利诺伊大学香槟分校，化学工程，博士

工作经历
2015-2017，伊利诺伊大学香槟分校，博士后
2017-至今，浙江大学，化学工程与生物工程学院，“****”研究员，博导

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合成生物学，代谢工程，CRISPR\/Cas9基因组编辑，蛋白质工程，无细胞蛋白质合成体系，生物炼制，生物化工\rSynthetic Biology, Metabolic Engineering, CRISPR\/Cas based Genome Editing, Protein Engineering, Cell-free Protein Synthesis, Biorefinery, Biochemical Engineering
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2017-07-17 12:36:45
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selfintroduction
连佳长博士，化学工程与生物工程学院研究员，博士生导师，入选浙江大学“****”。长期从事利用合成生物学的方法构建高效细胞工厂研究工作，i.e.构建了能够富集丙酮酸和乙酰辅酶A的平台细胞工厂；并发展了新的合成生物学工具，用于异源合成途径（i.e. DNA水平-质粒拷贝数；RNA水平-启动子工程；蛋白质水平-RBS工程等）以及宿主细胞代谢调控网络（i.e. 多功能CRISPR\/Cas系统）进行快速高效的优化和改造。此外，还从事蛋白质定向进化和无细胞蛋白质合成体系相关工作。共发表论文27篇，其中第一作者\/通讯作者文章17篇，包括Nature Communications,Metabolic Engineering, ACS Synthetic Biology, Biotechnology and Bioengineering, Applied Microbiology and Biotechnology等。受邀担任BMC Biotechnology副主编(Associate Editor)以及Metabolic Engineering, Applied Microbiology and Biotechnology, Biotechnology for Biofuels, Microbial Cell Factories, Journal of Industrial Microbiology and Biotechnology, Enzyme and Microbial Technology, Biochemical Engineering Journal, BMC Biotechnology等期刊审稿人。

教育背景
2003-2007，浙江大学，生物工程，学士
2007-2010，浙江大学，生物化工，硕士
2010-2015，伊利诺伊大学香槟分校，化学工程，博士

工作经历
2015-2017，伊利诺伊大学香槟分校，博士后
2017-至今，浙江大学，化学工程与生物工程学院，“****”研究员，博导
Profiles
Dr. Jiazhang Lian is a principle investigatorin the College of Chemical and Biological Engineering at Zhejiang University. His research focuses on the construction and optimization of cell factories using metabolic engineering and synthetic biology approaches.One sucheffort is to construct platform cell factories with enhanced supply ofsome generalprecursor metabolites (i.e. pyruvate and acetyl-CoA)fthat can be used for efficient production ofvalue-added compounds. The other effort is to develop novel synthetic biology tools, particularly the CRISPR\/Cas based genome engineering tools, to facilitate the development of cell factories. His group is also interested inexpanding the developed synthetic biology tools in new applications in environment biotechnology and drug discovery.

Dr. Lianhas published around 27 peer-reviewed papers at high impact journals such as Nature Communications,Metabolic Engineering, ACS Synthetic Biology, andBiotechnology and Bioengineering, and given several presentations in international conferences, such as AIChE annual meetings, SEED, and SIMB annual meeting. His research achievements have won him a couple of prestigious fellowships and awards, such as the Drickamer Fellowship, Shen Postdoc Fellowship, and the Award to attend the Global Young Scientists Summit in Singapore. He is invited as an associate editor of the journalBMC Biotechnologyand peer reviewers for a panel of biotechnology related journals, such asMetabolic Engineering, Applied Microbiology and Biotechnology, Biotechnology for Biofuels, Microbial Cell Factories, Journal of Industrial Microbiology and Biotechnology, Enzyme and Microbial Technology, Biochemical Engineering Journal, BMC Biotechnology.

Education Background
2003-2007, B.S., Bioengineering, Zhejiang University
2007-2010, M.S., Biochemical Engineering, Zhejiang University
2010-2015, Ph.D., Chemical Engineering, University of Illinois at Urbana-Champaign

Work Experience
2015-2017, Postdoctoral Fellow, University of Illinois at Urbana-Champaign2017-Present, Principle Investigator, Zhejiang University


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jzlian@zju.edu.cn
address
浙江大学玉泉校区合成生物学研究中心209
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2021-01-24 21:15:07
content
连佳长博士，生物质化工教育部重点实验室副主任，化学工程与生物工程学院研究员，博士生导师，入选国家级青年人才计划和浙江大学“****”，浙江省****基金获得者。主要从事基于合成生物学原理和基因组编辑技术的人工细胞工厂创建研究。共发表论文40余篇，包括Nature Communications,Metabolic Engineering, ACS Synthetic Biology, Biotechnology and Bioengineering, Applied Microbiology and Biotechnology等。受邀担任BMC Biotechnology Associate Editor、《合成生物学》编委、Frontiers in Biotechnology and Bioengineeringrs in Biotechnology and Bioengineering客座编辑以及Nature Chemical Biology,Metabolic Engineering, Applied Microbiology and Biotechnology, Biotechnology for Biofuels, Microbial Cell Factories, Journal of Industrial Microbiology and Biotechnology, Enzyme and Microbial Technology, Biochemical Engineering Journal, BMC Biotechnology等期刊审稿人。

教育背景
2003-2007，浙江大学，生物工程，学士
2007-2010，浙江大学，生物化工，硕士
2010-2015，伊利诺伊大学香槟分校，化学工程，博士

工作经历
2015-2017，伊利诺伊大学香槟分校，博士后
2017-至今，浙江大学，化学工程与生物工程学院，“****”研究员，博导

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个人简介