姓 名: 杨静文
职 称: 副教授
导师身份: 浙江海洋大学硕士生导师
研究方向: 海洋生物学 分子及细胞生物学方向
Emai：yangjingwen@zjou.edu.cn
学习工作简历
2003年9月至2007年7月 山东理工大学 学士
2007年9月至2010年7月 中国科学院海洋研究所 硕士
2010年9月至2013年6月 浙江大学动物科学学院 博士
2013年7月至2018年8月 浙江海洋大学海洋科学与技术学院 讲师
2017年9月至2018年9月 加州大学旧金山分校CSC访问****
2018年9月至 今 浙江海洋大学海洋科学与技术学院 副教授
研究兴趣
GPCR参与的海洋生物生理功能调控
海洋生物神经内分泌调控网络
科研项目
1、大黄鱼褪黑素信号系统特征及其生殖调控机理研究（**） 国家自然科学基金面上项目2021.01-2024.12（主持）
2、大黄鱼神经肽Y2亚族受体的信号转导机制及其生理功能研究(**)国家自然科学基金青年项目2017.01-2019.12（主持）
3、曼氏无针乌贼生殖生长调控神经肽高活性表达研究及评价（2017C32074） 浙江省公益技术研究项目2016.07-2018.06（主持）
4、刺参生殖与夏眠生理状态转变的神经内分泌调控特征及机理研究（**）国家自然科学基金面上项目2021.01-2024.12（主要参与人）
5、刺参Kisspeptin/GPR54系统特征及其生殖调控机制研究（**）国家自然科学基金面上项目2019.01-2022.12（主要参与人）
6、5-HTR介导的信号转导对刺参夏眠期间摄食的调控及其机理研究（**）国家自然科学基金青年项目2015.01-2017.12（主要参与人）
代表性论文著作
1.TianmingWang,Jing Liang, Xiaowei Xiang, Xu Chen, Bing Zhang, Naiming Zhou, Wei Huang,Jingwen Yang*. Pharmacological characterization, cellular localization and expression profile of NPY receptor subtypes Y2 and Y7 in large yellow croaker,Larimichthys crocea. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 2019, 238:110347.
2.Tianming Wang, Xu Chen, Ke Xu, Bing Zhang, Dexiang Huang,Jingwen Yang*. Apoptosis Induction and Detection in a Primary Culture of Sea Cucumber Intestinal Cells. Journal of Visualized Experiments, 2020(155).
3.Tianming Wang*, Jing Liang, Xiaowei Xiang, Jiajie Yuan, Xu Chen, Xingwei Xiang,Jingwen Yang*.Functional identification and expressional responses of large yellow croaker (Larimichthys crocea) interleukin-8 and its receptor.Fish & Shellfish Immunology, 2019, 87: 470-477
4.Jingwen Yang, Yuchao Xu, Ke Xu, Hongling Ping, Huilai Shi, Zhenming Lv, Changwen Wu, Tianming Wang*. Molecular cloning and transcriptional analysis of a npy receptor-like in common chinese cuttlefishSepiella japonica. Chinese Journal of Oceanology and Limnology, 2018, 36(3): 892-904
5.Jingwen Yang，Yunjun Yan，Xiaowei Xiang，Yuchao Xu，Naiming Zhou*，Tianming Wang*，Detection of ligand-activated G protein coupled receptorinternalization by confocal microscopy.Journal of Visualized Experiments, 2017,(122):55514
6.Jingwen Yang, Zhangfei Shen, Xue Jiang, Huipeng Yang, Haishan Huang, Lili Jin, Yajie Chen, Liangen Shi*, Naiming Zhou*. Agonist-activated Bombyx corazonin receptor is internalized via an arrestin-dependent and clathrin-independent pathway. Biochemistry, 2016, 55(28): 3874-3887
7.Jingwen Yang, Huihui Liu, Gang Zheng, Xiaowei Xiang, Zhenming Lv*, Tianming Wang*. Cathepsin L of the sea cucumber Apostichopus japonicus-molecular characterization and transcriptional response to Vibrio splendidus infection. Fish & Shellfish Immunology, 2016, 49: 387-395
8.Jingwen Yang, Haishan Huang, Huipeng Yang, Xiaobai He, Xue Jiang, Ying Shi, Damirin Alatangaole, Liangen Shi*, Naiming Zhou*. Specific activation of the G protein-coupled receptor BNGR-A21 by the neuropeptide corazonin from the silkworm, Bombyx mori, dually couples to the G(q) and G(s) signaling cascades. Journal of Biological Chemistry, 2013, 288(17): 11662-11675
9. Dexiang Huang, Bing Zhang, Tao Han, Guangbin Liu, Xu Chen, Zihao Zhao, Jiaqian Feng,Jingwen Yang,Tianming Wang*. Genome-wide prediction and comparative transcriptomic analysis reveals the G protein-coupled receptors involved in gonadal development ofApostichopus japonicus,Genomics, 2021,113, 967-978.
10.Tianming Wang*, Zheng Cao, Zhangfei Shen,Jingwen Yang, Xu Chen, Zhen Yang, Ke Xu, Xiaowei Xiang, Qiuhan Yu, Yimin Song, Weiwei Wang, Yanan Tian, Lina Sun, Libin Zhang, Su Guo, Naiming Zhou*. Existence and functions of a kisspeptin neuropeptide signaling system in a non-chordate deuterostome species. eLife, 2020, 9. 53370
11.Yunjun Yan, Tianming Wang, Wan Liu, Changwen Wu, Aiyi Zhu, Changfeng Chi, Zhenming Lv*,Jingwen Yang*. Identification and Expression Profile of the Gonadotropin-Releasing Hormone Receptor in Common Chinese Cuttlefish,Sepiella japonica. Journal of Experimental Zoology Part A-Ecological Genetics and Physiology, 2016, 325(7): 453-466
12.Zhenming Lv, Wan Liu, Liqing Liu, Tianming Wang, Huilai Shi, Hongling Ping, Changfeng Chi,Jingwen Yang*, Changwen Wu. Cloning, Characterization, and Expression Profile of Estrogen Receptor in Common Chinese Cuttlefish,Sepiella japonica. Journal of Experimental Zoology Part A-Ecological Genetics and Physiology, 2016, 325(3): 181-193
13.Jingwen Yang, Suping Zhang*. The radular morphology of Nassariidae (Gastropoda: Caenogastropoda) from China, Chinese Journal of Oceanology and Limnology, 2011, 29(5): 1023-1032
14.Jingwen Yang, Suping Zhang*. A new spceies of Nassarius (Gastropoda, Nassariidae) from the northern China seas, Acta Oceanologica Sinica, 2011, 30(6): 82-85
15.Huipeng Yang, Xiaobai He,Jingwen Yang, Xiaoyan Deng, Yuan Liao, Zhifang Zhang, Chenggang Zhu, Ying Shi, Naiming Zhou*, Activation of cAMP-response element-binding protein is positively regulated by PKA and calcium-sensitive calcineurin and negatively byPKC in insect., Insect Biochemistry and Molecular Biology, 2013, 43（11）：1028-1036