博士，浙江省“钱江****”****，博士生导师。2009年毕业于福州大学化学化工学院，获分析化学博士学位；2009年6月进入新加坡南洋理工大学从事博士后研究工作；2011年9月回国，进入福州大学工作，2016年破格增列为博士生导师，2017年破格晋升为教授；2019年11月调入嘉兴学院工作。主要从事局域表面等离子共振（LSPR）在临床医学、环境及食品安全分析等方面的基础及应用研究。近五年作为项目负责人主持包括国家自然科学基金、教育部留学回国基金、福建省高校新世纪优秀人才支持计划、福建省高校****、福建省自然科学基金等科研项目20余项。已在本学科权威期刊发表SCI收录论文150余篇，相关论文被他引3000余次，H-index 35。2019年入选浙江省151人才工程培养计划（第一层次）；2018年入选福建省新世纪优秀人才支持计划、2017年获第十四届福建青年科技奖、福建省自然科学优秀论文二等奖；2016年获第二十三届运盛青年科技奖；2015年获第二届福州青年科技奖、福建省科技进步三等奖；2014年获福建省科技进步三等奖；2013年入选福建省高校****人才培育计划；2012年获福建省科技进步二等奖。
研究领域:
表面增强拉曼光谱；
纳米可视化传感；
现代分离分析。

主持项目:
浙江省重点研发计划（640万）：农产品重要危害物快速准确检测关键技术研究与应用-基于阿达玛变换拉曼光谱的便携式微囊藻毒素亚型快速检测仪器集成关键技术研究与应用（2020C02022，2020.1-2022.12）
国家自然科学基金（面上项目，77.84万）：呼出气体冷凝液中痕量生物标志物的表面增强电化学发光成像分析（**，2017/1-2020/12)。
国家自然科学基金（面上项目，80万）：基于表面增强电化学发光的重金属、兽药残留分析及其迁移规律研究（**，2013/1-2016/12)。
国家自然科学基金（青年项目，25万）：基于非对称修饰贵金属纳米粒子LSPR耦合的食品安全传感器的研制与应用（**，2013/1-2015/12)。
福建省卫生教育联合攻关计划项目：基于HTLV-1病毒核酸适配体的靶向抗病毒质谱研究（2019-WJ-13，35万，2019-2022）
福建省高校新世纪优秀人才支持计划：纳米医药与纳米生物传感（**, 12万，2019.1-2021.12）
厦门市第十批“双百计划”（创业类）领军人才（200万，2018.1-2022.12）
第六批留学人员来闽创业启动支持计划：多彩可视化精子活力检测试剂盒的开发与产业化（重点资助项目，福建省人社厅资助50万，2018.1-2022.12）

代表论文（近三年）
Palanisamy Kannan, Longhua Guo*, Nanosensors for Smart Cities-Chapter 20: Nanosensors for food safety, Micro and Nano Technologies series, Copyright ? 2020 Elsevier Inc., 2020, 339-354. （论著）
Yuanjin Zhan, Yanbo Zeng, Lei Li, Longhua Guo,^*Fang Luo, Bin Qiu,^*Youju Huang,and Zhenyu Lin.Cu²⁺-Modified Boron Nitride Nanosheets Supported Sub-nanometer Gold Nanoparticles: AnOxidase-Mimicking Nanoenzyme with Unexpected Oxidation Properties. Anal. Chem.2020, 92, 1, 1236-1244
Jiao Yang, Qian Xia, Longhua Guo*, Fang Luo, Yongqiang Dong*, Bin Qiu, Zhenyu Lin. Highly Sensitive Signal-on Biosensor for MicroRNA 142-3p Based on the Quenching of Ru(bpy)3 2+-TPA Electrochemiluminescence by Carbon Dots and Duplex Specific Nuclease Assisted Target Recycling Amplification. Chem. Commun., 2020, Advance Article.
Core-satellite assemblies and exonuclease assisted double amplification strategy for ultrasensitive SERS detection of biotoxin. Dandan Huang, Jiaming Chen, Li Ding, Longhua Guo*, Palanisamy Kannan*, Fang Luo, Bin Qiu, Zhenyu Lin*；Anal Chim Acta, 2020, 1110: 56-63. 2020 May 08
Daifang Wang,^aJin Zhou,^aLonghua Guo, *^bBin Qiu^cand Zhenyu Lin*. Surface-enhanced Electrochemiluminescence Sensor Based on Au-SiO₂core-shell nanocomposites doped with Ru(bpy)₃²⁺for Ultrasensitive Detection of Prostate specific Antigen in Human Serum. Analyst,2020,145, 132 - 138. 10.1039/C9AN01935A
PalanisamyKannan*, ThandavarayanMaiyalagan, BingyongLin, WangLei, ChenJie,LonghuaGuo*, ZhongqingJiang,ShunMao,PalaniappanSubramanian. Nickel-phosphate pompon flowers nanostructured network enables the sensitive detection of microRNA. Talanta. 2020, 209, 120511. 1 March 2020
Bingyong Lin, Palanisamy Kannan*, Bin Qiu, Zhenyu Lin, and Longhua Guo*. On-spot surface enhanced Raman scattering detection of Aflatoxin B1 in peanut extracts using gold nanobipyramids evenly trapped into the AAO nanoholes. Food Chem.2020, 307, 125528.
Palanisamy Kannan,*Thandavarayan Maiyalagan,Alagarsamy Pandikumar, Longhua Guo,*Pitchaimani Veerakumarand Perumal Rameshkumar Highly sensitive enzyme-free amperometric sensing of hydrogen peroxide in real samples based on Co₃O₄nanocolumn structures. Anal. Methods, 2019,11, 2292-2302
Bingyong Lin, Jiaming Chen, Yanbo Zeng, Lei Li*, Bin Qiu, Zhenyu Lin, and Longhua Guo*. A Facile Approach for On-Site Evaluation of Nicotine in Tobacco and Environmental Tobacco Smoke. ACS Sensors.2019, 47, 1844-1850
Xiaoming Ma, Shan He, Bin Qiu, Fang Luo, Longhua Guo*,and Zhenyu Lin*. Noble Metal Nanoparticle-Based Multicolor Immunoassays: An Approach toward Visual Quantification of the Analytes with the Naked Eye.ACS Sensors,2019,4,4,782-791(Invited Perspective)
Yuanjin Zhan, Yanbo Zeng, Lei Li*, Fang Luo, Bin Qiu, Zhenyu Lin, Longhua Guo*. Ratiometric Fluorescent Hydrogel Test Kit for On-Spot Visual Detection of Nitrite. ACS Sens.2019, 4(5), 1252-1260.
Yi Lin, Palanisamy Kannan, Yanbo Zeng, Bin Qiu, Longhua Guo,* and Zhenyu Lin. Enzyme-free Multicolor Biosensor Based on Cu²⁺-Modified Carbon Nitride Nanosheets and Gold Nanobipyramids for Sensitive Detection of Neuron Specific Enolase. Sensor. Actuat. B-Chem.2019,283,138–145.
YuanjinZhan, JiaoYang, LonghuaGuo*, FangLuo, BinQiu*, GuolinHong*, ZhenyuLin. Targets regulated formation of boron nitride quantum dots – Gold nanoparticles nanocomposites for ultrasensitive detection of acetylcholinesterase activity and its inhibitors. Sensor. Actuat. B-Chem.2019, 279, 61-68
Huiping Fu, Jiaming Chen, Lijuan Chen, Xi Zhu, Zhuling Chen*, Bin Qiu, Zhenyu Lin, Longhua Guo*, and Guonan Chen. A calcium alginate sponge with embedded gold nanoparticles as a flexible SERS substrate for direct analysis of pollutant dyes.Microchimica Acta. 2019, 186: 64. https://doi.org/10.1007/s00604-018-3173-z
Bingyong Lin, Jiaming Chen, Palanisamy Kannan,* Yanbo Zeng, Bin Qiu, Longhua Guo,*and Zhenyu Lin. Rapid synthesis of a highly active and uniform 3-dimensional SERS substrate for on-spot sensing of dopamine. Microchimica Acta. 2019, 186(4):260. DOI: 10.1007/s00604-019-3357-1.
Zhonghui Chen, Chaoqun Chen, Huawei Huang, Fang Luo, Longhua Guo*,Lan Zhang*, Zhenyu Lin*, and Guonan Chen. Target-Induced Horseradish Peroxidase Deactivation for Multicolor Colorimetric Assay of Hydrogen Sulfide in Rat Brain Microdialysis.Anal. Chem., 2018, 90 (10), 6222–6228.
Jiancong Ni，Weiqiang Yang,Qingxiang Wang, Fang Luo, Longhua Guo*,Bin Qiu,Zhenyu Lin*,Huanghao Yang. Homogeneous and label-free electrochemiluminescence aptasensor based on the difference of electrostatic interaction and exonuclease-assisted target recycling amplification, Biosens. Bioelectron.,2018, 105, 182-187.
Jiaming Chen#, Longhua Guo#(co-first author), Bin Qiu, Zhenyu Lin*and Tie Wang*, Application of ordered nanoparticle self-assemblies in surface-enhanced spectroscopy. Mater. Chem. Front.,2018,2, 835-860.
Yingzhou Tao, Jiao Yang, Lijuan Chen, Youju Huang*, Bin Qiu,Longhua Guo*, Zhenyu Lin*.Dialysis assisted ligand exchange on gold nanorods: Amplification of the performance of a lateral flow immunoassay for E. coli O157:H7. Microchim Acta 2018,185(7):350.
Mengmeng Zhao, Peilong Wang, Yajuan Guo, Lixu Wang, Fang Luo, Bin Qiu, Longhua Guo*, Xiaoou Su^*, Zhenyu Lin, and Guonan Chen. Detection of aflatoxin B1 in food samples based on target-responsive aptamer-cross-linked hydrogel using a handheld pH meter as readout. Talanta, 2018, 176,34-39.
Yi Lin#, Shaohua Xu#, Jiao Yang, Youju Huang,* Zhitao Chen, Bin Qiu, Zhenyu Lin, Guonan Chen, and Longhua Guo*. Interesting optical variations of the etching of Au Nanobipyramid@Ag Nanorods and its application as a colorful chromogenic substrate for immunoassays. Sensor. Actuat. B-Chem.2018, 267, 502-509.
Lixu Wang, Chaoqun Chen, Huawei Huang, Da Huang?, Fang Luo, Bin Qiu,Longhua Guo?, Zhenyu Lin, Huanghao Yang. Sensitive detection of telomerase activity in cancer cells using portable pHmeter as readout. Biosens. Bioelectron., 2018, 121, 153-158.
Xiaoming Ma, Sun Mi, Yue Lin, Yinjin Liu, Fang Luo, Longhua Guo*, Bin Qiu, Zhenyu Lin* and Guonan Chen. Progress of Visual Biosensor Based on Gold Nanoparticles. Chinese Journal of Analytical Chemistry, 2018, 46(1), 1-10. (English Edition)

获授权专利
一种快速制备表面增强拉曼活性基底的方法；申请日：2018.01.29；授权公告日：2019.11.12；专利号：ZL 20**（第一发明人）
一种快速检测水中余氯的碳纳米材料及其配套装置与使用方法；申请日：2017.09.27；授权公告日：2019.09.13；专利号：ZL20**（第一发明人）
一种比率荧光纳米探针及其应用；申请日：2017.09.27；授权公告日：2019.05.10；专利号：ZL20**（第一发明人）
一种泡泡水增彩剂及其使用方法；申请日：2016.05.11；授权公告日：2018.03.16；专利号：ZL20**（第一发明人）
一种基于纳米金生长的可视化免疫分析方法；申请日：2015.11.23；授权公告日：2017.04.12；专利号：ZL20**（第一发明人）


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