金 毅（博士，研究员，博士生导师）专业：药物化学
主讲课程：自2006年参加有机化学实验、生物制药与生物技术、生药学课主讲。
团队：药物及药物中间体合成及研究团队
电子信箱：jinyi@ynu.edu.cn
课题组网页： www.jin-chem.cn
受教育经历及工作经历：
2006获中国科学院上海药物研究所博士学位；
1998年获兰州大学化学系学士学位；
2016-2017，美国密歇根大学安娜堡分校 药学院 访问****；
2007-2008，中国科学院昆明植物所博士后研究
2006至今，云南大学任教。
教学：
主讲生物制药与生物技术、生药学；
获2014年云南大学第6届教学成果一等奖。
研究领域和兴趣：
药物化学，有机合成化学，药物设计学
论文、专著：
1. Xi, L.; Wu, D.; Zhu, H.; Zhang, C.; Jin, Y.*; Lin, J. Improved and Large-Scale Synthesis of N-methyl-D-aspartic Acid. Current Organic Synthesis 2015, 12, 197-201.
2. Zhang, J.; Wu, D.; Jiang, K.; Zhang, D.; Zheng, X.; Wan, C.; Zhu, H.; Xie, X.; Jin, Y.*; Lin, J. Preparation, spectroscopy and molecular modelling studies of the inclusion complex of cordycepin with cyclodextrins. Carbohydrate Research 2015, 406, 55-64.
3. Gao, R.; Jin, Y.; Yang, Q.; Sun, B.; Lin, J. Study of stability and drug-excipient compatibility of estradiol and pharmaceutical excipients. Journal Of Thermal Analysis And Calorimetry 2015, 120, 839-845.
4. Ye, Q.; Li, X.; Jin, Y.*; Yu, J.; Chang, Q.; Jiang, J.; Yan, C.; Li, J.; Liu, W. 1-(2,6-Difluorobenzoyl)-Crystal Structures and Catalytic activity of dirhodium(II) Complexes with Axial Picoline Ligandsenyl)urea. Inorganica Chimica Acta 2015, 4(8), 540-546
5. An, X.; Liu, H.; Xu, Z.; Jin, Y.; Peng, X.; Yao, Y.; Geng, M.; Long, Y. Discovery of potent 1H-imidazo[4,5-b]pyridine-based c-Met kinase inhibitors via mechanism-directed structural optimization. Bioorganic & Medicinal Chemistry Letters 2015, 25, 708-716.
6. Jiang, K.; Dai, X.; Li, K.; Wu, D.; Zhang, J.; Jin, Y.*; Lin, J. Synthesis and In-Vitro Cytotoxicity of (E)-N,2,3-Triarylacrylamide Derivatives as Analogs of Combretastatin A-4. Medicinal Chemistry 2015, 11.
7. Jiang, J.; Wang, X.; Zhang, Y.; Jin, Y.* Lin, J. Advances in the inhibitors of Janus Kinase. Medicinal Chemistry 2014, 4(8), 540-546
8. Zhang, J.; Li, K.; Cong, Y.; Pu, S.; Zhu, H.; Xie, X.; Jin, Y.* Lin, J. Preparation, characterisation and bioactivity evaluation of the inclusion complex formed between picoplatin and gamma-cyclodextrin. Carbohydrate Research 2014, 396, 54-61.
9. Zhi, Y.; Gao, L.; Jin, Y.; Tang, C.; Li, J.; Li, J.; Long, Y. 4-Quinolone-3-carboxylic acids as cell-permeable inhibitors of protein tyrosine phosphatase 1B. Bioorganic & Medicinal Chemistry 2014, 22, 3670-3683.
10. Xiao, C.; Li, K.; Huang, R.; He, G.; Zhang, J.; Zhu, L.; Yang, Q.; Jiang, K.; Jin, Y.* Lin, J. Investigation of inclusion complex of Epothilone A with cyclodextrins. Carbohydrate Polymers 2014, 102, 297-305.
11. Fan, J.; Yang, Q.; He, G.; Xie, X.; Zhu, H.; Jin, Y.* Lin, J. Efficient and regioselective synthesis of bicyclic pyrrolidones or bicyclic pyridones by cyclocondensation of heterocyclic ketene aminals with nitro-phenylpropiolate. Rsc Advances 2014, 4, 28852-28855.
科研项目、成果和专利：
1. Design, synthesis and biological activity evaluation of tumor inhibitors based on the structure of VEGFR-2 kinase protein (主持国家自然科学基金Nos:**)
2. Design, synthesis and antitumor activity of a new type of novel double ring and the tubulin polymerization inhibitor (主持国家自然科学基金Nos:**)