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中科院昆明植物研究所研究生导师简介-邸迎彤

昆明植物研究所 免费考研网/2016-01-27

姓  名:
邸迎彤
学  科:
药物化学
电话/传真:
**
电子邮件:
diyt@mail.kib.ac.cn
通讯地址:
云南昆明蓝黑路132号 650201
更多信息:


简历:
2011/4 – 2012/4 加利福尼亚大学洛杉矶分校(UCLA),真菌次生代谢产物基因组挖矿,访问学者,导师:Yi Tang

2009/1 - 至今,中国科学院昆明植物研究所,植物化学与植物资源持续利用国家重点实验室,副研究员

2007/1 - 2008/2,中国科学院昆明植物研究所,植物化学与植物资源持续利用国家重点实验室,助理研究员

2004/3 - 2007/1,中国科学院昆明植物研究所,植物化学,理学博士,导师:郝小江

2000/9 - 2003/6,中国科学院成都生物所,天然产物化学,理学硕士,导师:丁立生

1996/7 - 2000/8,山西省瑞丰制药有限公司,开发部研发人员

1992/9 - 1996/6,兰州大学,生物系生物化学专业, 理学学士
研究领域:
主要研究方向为天然产物的化学生物学,综合运用有机化学、生物信息学、分子生物学、生物化学、分析化学、基因工程及代谢工程等学科知识与实验技术手段,进行以下三个方面研究:

1、真菌活性次生代谢产物生物合成途径及酶催化机制研究;

2、针对天然产物研究中的关键原始创新点----靶标/药物新结合位点的发现展开研究,阐明活性天然产物的作用靶标及其作用机制;

3、活性天然产物的合成生物学研究。
社会任职:

获奖及荣誉:
1、2014年获云南省学术与技术带头人;

2、2009年获云南省自然科学一等奖(排名第二);

3、2007年中国科学院院长奖。
代表论著:
1. Fang, X.; Di, Y. -T.; Zhang, Y.; Xu, Z. P.; Lu, Y.; Chen, Q. Q.; Zheng, Q. T.; Hao, X. J., Unprecedented Quassinoids with Promising Biological Activity from Harrisonia perforata. Angew. Chem., Int. Ed. 2015, 54, 5592?5595. (Co-first author)

2. Tan, C.-J.; Zhang, Y.; Kong, N.-C.; Di, Y.-T.; Hao, X.-J., Further Alkaloids from the Leaves of Trigonostemon lii. Helv. Chim. Acta 2015, 98, 72?77. (Co-correspondent author)

3. Yin, J.-L.; Fang, X.; Liu, E.-D.; Yuan, C.-M.; Li, S.-F.; Zhang, Y.; He, H.-P.; Li, S.-L.; Di, Y.-T.; Hao, X.-J., Phragmalin Limonoids from the Stem Barks of Chukrasia tabularis var. velutina. Planta Med. 2014, 80, 1304?1309. (Co-correspondent author)

4. Wang, K.-B.; Yuan, C.-M.; Xue, C.-M.; Li, D.-H.; Jing, Y.-K.; He, H.-P.; Hao, X.-J.; Di, Y.-T.; Li, Z.-L.; Hua, H.-M., Pegaharmalines A and B, two novel β-carboline alkaloids with unprecedented carbon skeletons from Peganum harmala. RSC Adv. 2014, 4, 53725?53729. (Co-correspondent author)

5. Wang, K.-B.; Di, Y.-T.; Bao, Y.; Yuan, C.-M.; Chen, G.; Li, D.-H.; Bai, J.; He, H.-P.; Hao, X.-J.; Pei, Y.-H.; Jing, Y.-K.; Li, Z.-L.; Hua, H.-M., Peganumine A, a β-Carboline Dimer with a New Octacyclic Scaffold from Peganum harmala. Org. Lett. 2014, 16, 4028?4031.

6. Li, X.-H.; Cao, M.-M.; Zhang, Y.; Li, S.-L.; Di, Y.-T.; Hao, X.-J., Fluevirines A-D, four new securinega-type alkaloids from Flueggea virosa. Tetrahedron Lett. 2014, 55, 6101?6104. (Co-correspondent author)

7. Fu, Y.-H.; Di, Y.-T.; He, H.-P.; Li, S.-L.; Zhang, Y.; Hao, X.-J., Angustifonines A and B, Cytotoxic Bisindole Alkaloids from Bousigonia angustifolia. J. Nat. Prod. 2014, 77, 57?62.

8. Di, Y.-T.; Wee, C.-S.; Li, C.-S.; Kong, N.-C.; Wang, J.-S.; Fang, X.; Zhu, H.-J.; Wu, Y.-D.; Hao, X.-J., Longphyllinesides A and B: natural Diels-Alder adducts from Daphniphyllum longeracemosum? Tetrahedron 2014, 70, 4017?4021.

9. Zhang, Q.; Zhang, Y.; Yang, T.-Q.; Di, Y.-T.; Hao, X.-J., Longeracemine, an unprecedented C-7/C-9 bonding alkaloid from Daphniphyllum longeracemosum. RSC Adv. 2013, 3, 9658?9661. (Co-correspondent author)

10. Cao, M.-M.; Wang, L.; Zhang, Y.; He, H.-P.; Gu, Y.-C.; Zhang, Q.; Li, Y.; Yuan, C.-M.; Li, S.-L.; Di, Y.-T.; Hao, X.-J., Daphmacromines K-O, alkaloids from Daphniphyllum macropodum. Fitoterapia 2013, 89, 205?209. (Co-correspondent author)

11. Zhang, Y.; He, H.-P.; Guo, L.-L.; Li, S.-F.; Di, Y.-T.; Hao, X.-J., Daphhimalenines C and D. New alkaloids from Daphniphyllum himalense. Z. Naturforsch., B: J. Chem. Sci. 2012, 67, 407?410. (Co-correspondent author)

12. Zhang, Q.; Zhang, Y.; He, H.-P.; Di, Y.-T.; Hao, X.-J., Trichilone, a new C21 steroid from Trichilia connaroides. Nat. Prod. Commun. 2012, 7, 1267?1268. (Co-correspondent author)

13. Li, S.-F.; Di, Y.-T.; Luo, R.-H.; Zheng, Y.-T.; Wang, Y.-H.; Fang, X.; Zhang, Y.; Li, L.; He, H.-P.; Li, S.-L.; Hao, X.-J., Cycloartane triterpenoids from Cassia occidentalis. Planta Med. 2012, 78, 821?827.

14. Zhang, Z.; Zhang, Y.; Wang, Y. H.; Zhang, Q.; Yan, X. H.; Di, Y. T.;He, H. P.; Hao, X. J., Three novel beta-carboline alkaloids from Gelsemium elegans. Fitoterapia 2012, 83, 704?708.

15.Zhang, Y.; He, H.-P.; Guo, L.-L.; Li, S.-F.; Di, Y.-T.;Hao, X.-J., Daphhimalenines C and D. New alkaloids from Daphniphyllum himalense. Z. Naturforsch., B: J. Chem. Sci. 2012, 67, 407?410.(Co-correspondent author)

16.Yuan, C.-M.; Zhang, Y.;Tang, G.-H.; Li, S.-L.; Di, Y.-T.;Hou, L.; Cai, J.-Y.; Hua, H.-M.; He, H.-P.; Hao, X.-J., Senegalensions A-C, Three Limonoids from Khaya senegalensis. Chem.--Asian J. 2012, 7, 2024?2027.

17.Wang, L.; He, H.-P.; Di, Y.-T.; Zhang, Y.; Hao, X.-J., Catharoseumine, a new monoterpenoid indole alkaloid possessing a peroxy bridge from Catharanthus roseus. Tetrahedron Lett. 2012, 53, 1576?1578.

18.Tian, J.-M.; Ou-Yang, S.-S.; Zhang, X.; Di, Y.-T.; Jiang, H.-L.; Li, H.-L.; Dai, W.-X.; Chen, K.-Y.; Liu, M.-L.; Hao, X.-J.; Shen, Y.-H.; Luo, C.; Zhang, W.-D., Experimental and computational insights into the conformations of tunicyclin E, a new cycloheptapeptide from Psammosilene tunicoides. RSC Adv. 2012, 2, 1126?1135.

19.Tang, G.-H.; Zhang, Y.; Gu, Y.-C.; Li, S.-F.; Di, Y.-T.; Wang, Y.-H.; Yang, C.-X.; Zuo, G.-Y.; Li, S.-L.; He, H.-P.; Hao, X.-J., Trigoflavidols A-C, degraded diterpenoids with antimicrobial activity, from Trigonostemon flavidus. J. Nat. Prod. 2012, 75,996?1000.

20.Tan, C.-J.; Wang, Y.-H.; Di, Y.-T.;He, H.-P.; Mu, S.-Z.; Li, S.-F.; Zhang, Y.; Hao, X.-J., Daphnioldhamine A, a novel alkaloid from Daphniphyllum oldhami. Tetrahedron Lett. 2012, 53, 2588?2591.

21.Li, S.-F.; Zhang, Y.; Li, Y.; Li, X.-R.; Kong, L.-M.; Tan, C.-J.; Li, S.-L.; Di, Y.-T.; He, H.-P.; Hao, X.-J., β-Carboline alkaloids from the leaves of Trigonostemon liiY.T. Chang. Bioorg. Med. Chem. Lett. 2012, 22, 2296?2299.

22.Li, S.-F.; Di, Y.-T.; Luo, R.-H.; Zheng, Y.-T.; Wang, Y.-H.; Fang, X.; Zhang, Y.; Li, L.; He, H.-P.; Li, S.-L.; Hao, X.-J., Cycloartane triterpenoids from Cassia occidentalis. Planta Med. 2012, 78, 821?827.

23.Guo, L.-L.; He, H.-P.; Di, Y.-T.; Li, S.-F.; Cheng, Y.-Y.; Yang, W.; Li, Y.; Yu, J.-P.; Zhang, Y.; Hao, X.-J., Indole alkaloids from Ervatamia chinensis. Phytochemistry.2012, 74, 140?145.

24.Fu, Y.; He, H.; Di, Y.;Li, S.; Zhang, Y.; Hao, X., Mekongenines A and B, two new alkaloids from Bousigonia mekongensis. Tetrahedron Lett. 2012, 53, 3642?3646.

25.Cheng, Y.-Y.; Li, S.-F.; Zhang, Y.; Tang, G.-H.; Di, Y.-T.; Hao, X.-J.; Li, S.-L.; He, H.-P., Cleidbrevoids A-C, new clerodane diterpenoids from Cleidion brevipetiolatum. Fitoterapia 2012, 83, 1100?1104.

26.Chen, G.; Yang, J.; Gao, S.; He, H.; Li, S.; Di, Y.;Chang, Y.; Lu, Y.; Hao, X., Spiro[pyrrolidine-2,3'-oxindole] derivatives synthesized by novel regioselective 1,3-dipolar cycloadditions. Mol. Diversity 2012, 16, 151?156.

27.Cao, M.; Zhang, Y.; He, H.; Li, S.; Huang, S.; Chen, D.; Tang, G.; Li, S.; Di, Y.;Hao, X., Daphmacromines A-J, Alkaloids from Daphniphyllum macropodum. J. Nat. Prod. 2012, 75, 1076?1082.

28.Cai, J.-Y.; Zhang, Y.; Luo, S.-H.; Chen, D.-Z.; Tang, G.-H.; Yuan, C.-M.; Di, Y.-T.; Li, S.-H.; Hao, X.-J.; He, H.-P., Aphanamixoid A, a Potent Defensive Limonoid, with a New Carbon Skeleton from Aphanamixis polystachya. Org. Lett. 2012, 14,2524?2527.

29.Zhu, F.; Di, Y.-T.; Li, X.-Y.; Liu, L.-L.; Zhang, Q.; Li, Y.; Hao, X.-J.; He, H.-P., Neoclerodane diterpenoids from Scutellaria barbata. Planta Med. 2011, 77, 1536?1541.

30.Zhang, Y.; Di, Y.-T.; He, H.-P.; Li, S.-F.; Lu, Y.; Gong, N.-B.; Hao, X.-J., Daphmalenines A and B: Two new alkaloids with unusual skeletons fromDaphniphyllum himalense. Eur. J. Org. Chem. 2011, 4103?4107, S4103/1?S4103/20.

31.Zhang, Q.; Di, Y.-T.; He, H.-P.; Fang, X.; Chen, D.-L.; Yan, X.-H.; Zhu, F.; Yang, T.-Q.; Liu, L.-L.; Hao, X.-J., Phragmalin-and Mexicanolide-Type Limonoids from the Leaves of Trichilia connaroides. J. Nat. Prod. 2011, 74, 152?157.

32.Yin, J.-L.; Di, Y.-T.; Fang, X.; Liu, E.-D.; Liu, H.-Y.; He, H.-P.; Li, S.-L.; Li, S.-F.; Hao, X.-J., Tabulvelutin A, the first 19-nor limonoid with unprecedented ring system from Chukrasia tabularisvar. velutina. Tetrahedron Lett. 2011, 52, 3083?3085.

33.Yi, P.; Di, Y.-T.; Liu, W.; Hao, X.-J.; Ming, Y.; Huang, D.-S.; Yang, J.; Yi, Z.-Z.; Li, Z.-J.; Yang, R.-D.; Zhang, J.-C., Protein-based alignment in 3D-QSAR of FBPase inhibitors. Eur. J. Med. Chem. 2011, 46, 885?892.

34.Yang, T.-Q.; Di, Y.-T.; He, H.-P.; Zhang, Q.; Zhang, Y.; Hao, X.-J., Further Alkaloids from the Fruits of Daphniphyllum longeracemosum. Helv. Chim. Acta 2011, 94, 397?403.

35.Yan, X.-H.; Di, Y.-T.; Fang, X.; Yang, S.-Y.; He, H.-P.; Li, S.-L.; Lu, Y.; Hao, X.-J., Chemical constituents from fruits of Harrisonia perforata. Phytochemistry.2011, 72, 508?513.

36.Ning, J.; Di, Y.-T.; Li, S.-F.; Geng, Z.-L.; He, H.-P.; Wang, Y.-H.; Wang, Y.-Y.; Li, Y.; Li, S.-L.; Hao, X.-J., Polyynes from Toona ciliatavar. ciliata and Related Cytotoxic Activity. Helv. Chim. Acta 2011, 94, 376?381.

37.Li, S.-F.; Di, Y.-T.; Li, S.-L.; Zhang, Y.; Yang, F.-M.; Sun, Q.-Y.; Simo, J. M.; He, H.-P.; Hao, X.-J., Trigonosins A-F, Daphnane Diterpenoids from Trigonostemon thyrsoideum. J. Nat. Prod. 2011, 74, 464?469.

38.Li, S.-F.; Di, Y.-T.; He, H.-P.; Zhang, Y.; Wang, Y.-H.; Yin, J.-L.; Tan, C.-J.; Li, S.-L.; Hao, X.-J., Trigonoines A and B, two novel alkaloids from the leaves of Trigonostemon lii. Tetrahedron Lett. 2011, 52, 3186-3188.

39.Fang, X.; Di, Y. T.;Hao, X. J., The advances in the limonoid chemistry ofthe Meliaceae family. Curr. Org. Chem. 2011, 15, 1363?1391.

40.Zhu, F.; Di, Y.-T.; Liu, L.-L.; Zhang, Q.; Fang, X.; Yang, T.-Q.; Hao, X.-J.; He, H.-P., Cytotoxic Neoclerodane Diterpenoids from Scutellaria barbata. J. Nat. Prod. 2010, 73, 233?236.

41.Zhang, Q.; Di, Y.-T.; He, H.-P.; Li, S.-L.; Hao, X.-J., Mitregenin, a new annonaceous acetogenin from Mitrephora maingayi. Nat. Prod. Commun. 2010, 5, 1793?1794.

42.Yang, T.; Di, Y.;He, H.; Hao, X., A new alkaloid from fruits of Daphniphyllum longeracemosum(daphniphyllaceae). Yunnan Zhiwu Yanjiu 2010, 32, 561?563.

43.Yan, X.-H.; Chen, J.; Di, Y.-T.; Fang, X.; Dong, J.-H.; Sang, P.; Wang, Y.-H.; He, H.-P.; Zhang, Z.-K.; Hao, X.-J., Anti-Tobacco Mosaic Virus (TMV) Quassinoids from Brucea javanica(L.) Merr. J. Agric. Food Chem. 2010, 58, 1572?1577.

44.Tan, C.-J.; Di, Y.-T.; Wang, Y.-H.; Zhang, Y.; Si, Y.-K.; Zhang, Q.; Gao, S.; Hu, X.-J.; Fang, X.; Li, S.-F.; Hao, X.-J., Three New Indole Alkaloids from Trigonostemon lii. Org. Lett. 2010, 12, 2370?2373.

45.Song, Z.-Q.; Mu, S.-Z.; Di, Y.-T.; Hao, X.-J., A new jatrophane diterpenoid from Euphorbia peplus. Zhongguo Tianran Yaowu 2010, 8, 81?83.

46.Ning, J.; He, H.-P.; Li, S.-F.; Geng, Z.-L.; Fang, X.; Di, Y.-T.; Li, S.-L.; Hao, X.-J., Triterpenoids from the leaves of Toona ciliata. J. Asian Nat. Prod. Res. 2010, 12, 448?452.

47.Ning, J.; Di, Y.-T.; Wang, Y.-Y.; He, H.-P.; Fang, X.; Li, Y.; Li, S.-L.; Hao, X.-J., Cytotoxic activity of trijugin-type limonoids from Cipadessa baccifera. Planta Med. 2010, 76, 1907?1910.

48.Ning, J.; Di, Y.-T.; Fang, X.; He, H.-P.; Wang, Y.-Y.; Li, Y.; Li, S.-L.; Hao, X.-J., Limonoids from the Leaves of Cipadessa baccifera. J. Nat. Prod. 2010, 73, 1327?1331.

49.Liu, L.-L.; Di, Y.-T.; Zhang, Q.; Fang, X.; Zhu, F.; Chen, D.-L.; Hao, X.-J.; He, H.-P., Aminocadambines A and B, two novel indole alkaloids from Neolamarckia cadamba. Tetrahedron Lett. 2010, 51, 5670?5673.

50.Liu, L.; Zhu, F.; Di, Y.; Hao, X.; He, H., Plumieride B, a new iridoid from Neolamarckia cadamba(Rubiaceae). Yunnan Zhiwu Yanjiu 2010, 32, 378?380.

51.Li, S.-F.; Di, Y.-T.; Wang, Y.-H.; Tan, C.-J.; Fang, X.; Zhang, Y.; Zheng, Y.-T.; Li, L.; He, H.-P.; Li, S.-L.; Hao, X.-J., Anthraquinones and Lignans from Cassia occidentalis. Helv. Chim. Acta 2010, 93, 1795?1802.

52.Li, C.-S.; Di, Y.-T.; Guo, J.; Zhang, Q.; Fang, X.; Hao, X.-J., Daphlongamines I and J. new Yuzurine-type alkaloids from Daphniphyllum longeracemosum. Z. Naturforsch., B: J. Chem. Sci. 2010, 65, 1406?1408.

53.Guo, J.; He, H.-P.; Fang, X.; Di, Y.-T.; Li, S.-L.; Zhang, Z.; Leng, Y.; Hua, H.-M.; Hao, X.-J., Kansuinone, a novel euphane-type triterpene from Euphorbia kansui. Tetrahedron Lett. 2010, 51, 6286?6289.

54.Guo, J.; Fang, X.; Di, Y. T.; Hua, H. M.; Hao, X. J., Kansuinine J, a new macrocyclic diterpenoid from the roots of Euphorbia kansui. Chin. Chem. Lett. 2010, 21, 943?946.

55.Geng, Z.-L.; Fang, X.; Di, Y.-T.; Zhang, Q.; Shen, Y.-M.; Hao, X.-J., A new limonoid from Trichilia connaroides. Z. Naturforsch., B: J. Chem. Sci. 2010, 65, 762?764.

56.Fang, X.; Di, Y.-T.; He, H.-P.; Hu, G.-W.; Li, S.-L.; Hao, X.-J., Chemical constituents of Toona microcarpa (C. DC.) Harms in Engl. (Meliaceae). Biochem. Syst. Ecol. 2010, 38, 128?130.(Co-correspondent author)

57.Fang, X.; Di, Y.;Geng, Z.; Tan, C.; Guo, J.; Ning, J.; Hao, X., Trichiliton A, a Novel Limonoid from Trichilia connaroides. Eur. J. Org. Chem. 2010, 1381?1387, S1381/1-S1381/29.(Co-correspondent author)

58.Zhu, F.; Liu, L.; Di, Y.; Hao, X.; He, H., Scutellin A, a new neoclerodane diterpenoid from Scutellaria barbata(Labiatae). Yunnan Zhiwu Yanjiu 2009, 31, 474?476.

59.Zhang, Z.; Di, Y.-T.; Wang, Y.-H.; Mu, S.-Z.; Fang, X.; Zhang, Y.; Tan, C.-j.; Zhang, Q.; Yan, X.-H.; Guo, J.; Li, C.-S.; Hao, X.-J., Gelegamines A-E: five new oxindole alkaloids from Gelsemium elegans. Tetrahedron 2009, 65, 4551?4556.(co-correspondent author)

60.Zhang, Y.; He, H.; Di, Y.; Wang, Y.; Gao, S.; Hao, X., Alkaloids from Daphniphyllum paxianum. Tianran Chanwu Yanjiu Yu Kaifa 2009, 21, 435?437, 505.

61.Zhang, Y.; Di, Y.-T.;Zhang, Q.; Mu, S.-Z.; Tan, C.-J.; Fang, X.; He, H.-P.; Li, S.-L.; Hao, X.-J., Daphhimalenine A, a New Alkaloid with an Unprecedented Skeleton, from Daphniphyllum himalense. Org. Lett. 2009, 11, 5414?5417.

62.Zhang, Y.; Di, Y.-T.; Mu, S.-Z.; Li, C.-S.; Zhang, Q.; Tan, C.-J.; Zhang, Z.; Fang, X.; Hao, X.-J., Dapholdhamines A-D, Alkaloids from Daphniphyllum oldhami. J. Nat. Prod. 2009, 72, 1325?1327.

63.Zhang, Q.; Di, Y.-T.; Li, C.-S.; Fang, X.; Tan, C.-J.; Zhang, Z.; Zhang, Y.; He, H.-P.; Li, S.-L.; Hao, X.-J., Daphenylline, a New Alkaloid with an Unusual Skeleton, from Daphniphyllum longeracemosum. Org. Lett. 2009, 11, 2357?2359.

64.Yang, X.-W.; He, H.-P.; Du, Z.-Z.; Liu, H.-Y.; Di, Y.-T.; Ma, Y.-L.; Wang, F.; Lin, H.; Zuo, Y.-Q.; Li, L.; Hao, X.-J., Tarennanosides A-H, eight new lignan glucosides from Tarenna attenuata and their protective effect on H2O2-induced impairment in PC12 cells. Chem. Biodiversity 2009, 6, 540?550.

65.Wang, Y.-S.; He, H.-P.; Yang, J.-H.; Di, Y.-T.; Tan, N.-H.; Hao, X.-J., Clausenain B, a phenylalanine-rich cyclic octapeptide from Clausena anisumolens. J. Braz. Chem. Soc. 2009, 20, 478?481.

66.Tian, J.; Yang, X.; Di, Y.;Ma, Y.; Li, L.; Li, L.; He, H.; Hao, X., Antioxidant lignans from Mananthes patentiflora. Planta Med. 2009, 75, 534?537.

67.Liu, H.-Y.; Ni, W.; Chen, C.-X.; Di, Y.-T.; Hao, X.-J., Two New Diterpenoid Lactams from Spiraea japonicavar. ovalifolia. Helv. Chim. Acta 2009, 92, 1198?1202.

68.Li, C.-S.; Di, Y.-T.; Zhang, Q.; Zhang, Y.; Tan, C.-J.; Hao, X.-J., Alkaloids from the leaves of Daphniphyllum longeracemosumRosenth. Helv. Chim. Acta 2009, 92, 653?659.

69.Kong, N.-C.; Zhang, Y.; Gao, S.; Lu, Y.; Zheng, Q.-T.; Sun, Q.-Y.; Yang, F.-M.; Di, Y.-T.; Hao, X.-J., Structural elucidation of daphniacetal A, a new oxa-cage compound isolated from Daphniphyllum macropodumMiq. Tetrahedron Lett. 2009, 50, 957?959.

70.Hu, X.-J.; Wang, Y.-H.; Kong, L.-Y.; He, H.-P.; Gao, S.; Liu, H.-Y.; Ding, J.; Xie, H.; Di, Y.-T.; Hao, X.-J., New phenanthrenes from Trigonostemon liiY.T. Chang. Tetrahedron Lett. 2009, 50, 2917?2919.(Co-correspondent author)

71.Hu, X.-J.; Di, Y.-T.; Wang, Y.-H.; Kong, L.-Y.; Gao, S.; Li, C.-S.; Liu, H.-Y.; He, H.-P.; Ding, J.; Xie, H.; Hao, X.-J., Carboline alkaloids from Trigonostemon lii. Planta Med. 2009, 75, 1157?1161.(Co-correspondent author)

72.Geng, Z.-L.; Fang, X.; Di, Y.-T.; Zhang, Q.; Zeng, Y.; Shen, Y.-M.; Hao, X.-J., Trichilin B, a novel limonoid with highly rearranged ring system from Trichilia connaroides. Tetrahedron Lett. 2009, 50, 2132?2134.

73.Gao, Z.-L.; He, H.-P.; Di, Y.-T.; Fang, X.; Li, C.-S.; Zhang, Q.; Zhao, P.-J.; Li, S.-L.; Hao, X.-J., Three New Pregnane Glycosides from Marsdenia tinctoria. Helv. Chim. Acta 2009, 92, 1775?1781.

74.Gao, Z.-L.; He, H.-P.; Di, Y.-T.; Fang, X.; Li, C.-S.; Liu, H.-Y.; Zhou, Q.-L.; Mu, Q.-Z.; Hao, X.-J., Gracillosides A-F, six new 8,14-seco-pregnane glycosides from Adelostemma gracillimum. Steroids 2009, 74, 694?700.

75.Fang, X.; Zhang, Q.; Tan, C.-J.; Mu, S.-Z.; Lu, Y.; Lu, Y.-B.; Zheng, Q.-T.; Di, Y.-T.; Hao, X.-J., Cipadonoids B-G, six new limonoids from Cipadessa cinerascens. Tetrahedron 2009, 65, 7408?7414.(Co-correspondent author)

76.Fang, X.; Di, Y.-T.; Li, C.-S.; Geng, Z.-L.; Zhang, Z.; Zhang, Y.; Lu, Y.; Zheng, Q.-T.; Yang, S.-Y.; Hao, X.-J., Tetranortriterpenoids from the leaves of Cipadessa cinerascens. J. Nat. Prod. 2009, 72, 714?718.

77.Fang, X.; Di, Y.-T.; Hu, G.-W.; Li, S.-L.; Hao, X.-J., Chemical constituents from Cipadessa cinerascens(Pellegr) Hand.-Mazz (Meliaceae). Biochem. Syst. Ecol. 2009, 37, 528?530.(Co-correspondent author)

78.Chen, J.; Yan, X.-H.; Dong, J.-H.; Sang, P.; Fang, X.; Di, Y.-T.; Zhang, Z.-K.; Hao, X.-J., Tobacco mosaic virus (TMV) inhibitors from Picrasma quassioidesBenn. J. Agric. Food Chem. 2009, 57, 6590?6595.

79.Zhu, X.-M.; Xie, P.; Di, Y.-T.; Peng, S.-L.; Ding, L.-S.; Wang, M.-K., Two new triterpenoid saponins from Gymnema sylvestre. J. Integr. Plant Biol. 2008, 50, 589?592.

80.Zhang, Y.; Di, Y.-T.; Liu, H.-Y.; Li, C.-S.; Tan, C.-J.; Zhang, Q.; Fang, X.; Li, S.-L.; Hao, X.-J., Three new alkaloids, paxiphyllines C-E, from Daphniphyllum paxianum. Helv. Chim. Acta 2008, 91, 2153?2158.

81.Zhang, Q.; Di, Y.-T.; Liu, H.-Y.; Kong, N.-C.; Gao, S.; Li, C.-S.; Zhang, Y.; Li, S.-L.; Hao, X.-J., Daphnoldines A and B, two new yuzurine alkaloids with a four-ring system, from the fruits of Daphniphyllum oldhamii. Helv. Chim. Acta 2008, 91, 914?919.

82.Wang, Y.-S.; He, H.-P.; Yang, J.-H.; Di, Y.-T.; Hao, X.-J., New monoterpenoid coumarins from Clausena anisumolens. Molecules 2008, 13, 931?937.

83.Tian, J.-M.; He, H.-P.; Di, Y.-T.; Yang, X.-W.; Gao, Z.-L.; Hao, X.-J., Three new lignan glycosides from Mananthes patentiflora. J. Asian Nat. Prod. Res. 2008, 10, 228?232.

84.Tan, C.; Di, Y.;Wang, Y.; Wang, Y.; Mu, S.; Gao, S.; Zhang, Y.; Kong, N.; He, H.; Zhang, J.; Fang, X.; Li, C.; Lu, Y.; Hao, X., Oldhamine A, a novel alkaloid from Daphniphyllum oldhami. Tetrahedron Lett. 2008, 49, 3376?3379.

85.Ren, Y.; Tang, Q.; Di, Y.;Zhang, Z.; He, H.; Li, S.; Hao, X., Chemical components of Cipadessa cinerascens(Pell.) Hand.-Mazz. Zhongcaoyao2008, 39, 1302?1303.

86.Mu, S.-Z.; Wang, J.-S.; Yang, X.-S.; He, H.-P.; Li, C.-S.; Di, Y.-T.; Wang, Y.; Zhang, Y.; Fang, X.; Huang, L.-J.; Hao, X.-J., Alkaloids from Daphniphyllum oldhami. J. Nat. Prod. 2008, 71, 564?569.

87.Liu, H.; Di, Y.;Yang, J.; Teng, F.; Lu, Y.; Ni, W.; Chen, C.; Hao, X., Three novel 3,4-seco-podocarpane trinorditerpenoids from Aleurites moluccana. Tetrahedron Lett. 2008, 49, 5150?5151.

88.Li, C.-S.; Di, Y.-T.; Mu, S.-Z.; He, H.-P.; Zhang, Q.; Fang, X.; Zhang, Y.; Li, S.-L.; Lu, Y.; Gong, Y.-Q.; Hao, X.-J., Daphniphyllum and Diterpenoid Alkaloids from Daphniphyllum longeracemosum. J. Nat. Prod. 2008, 71, 1202?1206.

89.Fang, X.; Di, Y.-T.; He, H.-P.; Liu, H.-Y.; Zhang, Z.; Ren, Y.-L.; Gao, Z.-L.; Gao, S.; Hao, X.-J., Cipadonoid A, a Novel Limonoid with an Unprecedented Skeleton, from Cipadessa cinerascens. Org. Lett. 2008, 10, 1905?1908.

90.Di, Y.-T.; Liu, L.-L.; Li, C.-S.; Zhang, Y.; Zhang, Q.; Mu, S.-Z.; Sun, Q.-Y.; Yang, F.-M.; Liu, H.-Y.; Hao, X.-J., Yunnandaphninines F and G, new C30 alkaloids from Daphniphyllum yunnanense. Helv. Chim. Acta 2008, 91, 838?843.

91.Zhang, Y.; He, H.; Di, Y.;Mu, S.; Wang, Y.; Wang, J.; Li, C.; Kong, N.; Gao, S.; Hao, X., Paxiphyllines A and B, new alkaloids from Daphniphyllum paxianum. Tetrahedron Lett. 2007, 48, 9104?9107.

92.Wang, Y.-H.; Zhang, Z.-K.; Yang, F.-M.; Sun, Q.-Y.; He, H.-P.; Di, Y.-T.; Mu, S.-Z.; Lu, Y.; Chang, Y.; Zheng, Q.-T.; Ding, M.; Dong, J.-H.; Hao, X.-J., Benzylphenethylamine Alkaloids from Hosta plantagineawith Inhibitory Activity against Tobacco Mosaic Virus and Acetylcholinesterase. J. Nat. Prod. 2007, 70, 1458?1461.

93.Wang, Y.-H.; Gao, S.; Yang, F.-M.; Sun, Q.-Y.; Wang, J.-S.; Liu, H.-Y.; Li, C.-S.; Di, Y.-T.; Li, S.-L.; He, H.-P.; Hao, X.-J., Structure Elucidation and Biomimetic Synthesis of Hostasinine A, a New Benzylphenethylamine Alkaloid from Hosta plantaginea. Org. Lett. 2007, 9, 5279?5281.

94.Ren, Y.-L.; Tang, Q.-R.; Di, Y.-T.; He, H.-P.; Zhang, Z.; Li, S.-L.; Hao, X.-J., Two new tetranortriterpenoids from Cipadessa cinerascens. Helv. Chim. Acta 2007, 90, 764?768.

95.Mu, S.-Z.; Yang, X.-W.; Di, Y.-T.; He, H.-P.; Wang, Y.; Wang, Y.-H.; Li, L.; Hao, X.-J., Secophnane-type alkaloids from Daphniphyllum oldhamii. Chem. Biodiversity 2007, 4,129?138.

96.Mu, S.-Z.; Li, C.-S.; He, H.-P.; Di, Y.-T.; Wang, Y.; Wang, Y.-H.; Zhang, Z.; Lu, Y.; Zhang, L.; Hao, X.-J., Daphnipaxianines A-D, alkaloids from Daphniphyllum paxianum. J. Nat. Prod. 2007, 70, 1628?1631.

97.Liu, H.-Y.; Gao, S.; Di, Y.-T.; Chen, C.-X.; Lu, Y.; Zhang, L.; Zheng, Q.-T.; Hao, X.-J., A novel atisane diterpenoid from Spiraea japonicavar. acuta. Helv. Chim. Acta 2007, 90, 1386?1390.

98.Li, C.-S.; Di, Y.-T.; He, H.-P.; Gao, S.;Wang, Y.-H.; Lu, Y.; Zhong, J.-L.; Hao, X.-J., Daphlongeranines A and B, Two Novel Alkaloids Possessing Unprecedented Skeletons from Daphniphyllum longeracemosum. Org. Lett. 2007, 9, 2509?2512.

99.Li, C.; He, H.; Di, Y.; Wang, Y.; Mu, S.; Li, S.; Gao, S.; Gao, Z.; Hao, X., Daphlongeramine A, novel Daphniphyllum alkaloid from Daphniphyllum longeracemosum. Tetrahedron Lett. 2007, 48, 2737?2740.

100.Kong, N.-C.; He, H.-P.; Wang, Y.-H.; Mu, S.-Z.; Di, Y.-T.; Hao, X.-J., Daphnimacropodines A-D, Alkaloids fromDaphniphyllum macropodum. J. Nat. Prod. 2007, 70, 1348?1351.

101.Gao, S.; Liu, H.-Y.; Wang, Y.-H.; He, H.-P.; Wang, J.-S.; Di, Y.-T.; Li, C.-S.; Fang, X.; Hao, X.-J., Lathyranone A: A Diterpenoid Possessing an Unprecedented Skeleton from Euphorbia lathyris. Org. Lett. 2007, 9, 3453?3455.

102.Di, Y.-T.; He, H.-P.; Wang, Y.-S.; Li, L.-B.; Lu, Y.; Gong, J.-B.; Fang, X.; Kong, N.-C.; Li, S.-L.; Zhu, H.-J.; Hao, X.-J., Isolation, X-ray Crystallography, and Computational Studies of Calydaphninone, a New Alkaloidfrom Daphniphyllum calycillum. Org. Lett. 2007, 9, 1355?1358.

103.Di, Y.-T.; He, H.-P.; Liu, H.-Y.; Yi, P.; Zhang, Z.; Ren, Y.-L.; Wang, J.-S.; Sun, Q.-Y.; Yang, F.-M.; Fang, X.; Li, S.-L.; Zhu, H.-J.; Hao, X.-J., Trijugin-Type Limonoids from the Leaves of Cipadessa cinerascens. J. Nat. Prod. 2007, 70, 1352?1355.

104.Zhou, Y.; Di, Y.-T.; Gesang, S.; Peng, S.-L.; Ding, L.-S., Secoiridoid glycosides from Swertia mileensis. Helv. Chim. Acta 2006, 89, 94?102.

105.Yang, X.-W.; Ma, Y.-L.; He, H.-P.; Wang, Y.-H.;Di, Y.-T.; Zhou, H.; Li, L.; Hao, X.-J., Iridoid Constituents of Tarenna attenuata. J. Nat. Prod. 2006, 69, 971?974.

106.Wang, J.; Yang, X.; Di, Y.-T.;Wang, Y.; Shen, Y.; Hao, X., Isoflavone diglycosides from Glycosmis pentaphylla. J. Nat. Prod. 2006, 69, 778-782.

107.Wang, J.; Di, Y.-T.;Yang, X.; Li, S.; Wang, Y.; Hao, X., Hydroquinone diglycoside acyl esters from the stems of Glycosmis pentaphylla. Phytochemistry 2006, 67, 486?491.

108.Mu, S.-Z.; Wang, Y.; He, H.-P.; Yang, X.-W.; Wang, Y.-H.; Di, Y.-T.; Lu, Y.; Chang, Y.; Hao, X.-J., Daphnioldhanins A-C, Alkaloids from Daphniphyllum oldhami. J. Nat. Prod. 2006, 69, 1065?1069.

109.Li, L.; He, H.-P.; Di, Y.-T.; Tian, J.-M.; Hao, X.-J., New alkaloids from Daphniphyllum longeracemosumRosenth. Helv. Chim. Acta 2006, 89, 1457?1462.

110.Li, L.; He, H.-P.; Di, Y.-T.; Gao, S.; Hao, X.-J., Daphnilongerine, an unprecedented fused pentacyclic ring system alkaloid from Daphniphyllum longeracemosumRosenth. Tetrahedron Lett. 2006, 47, 6259?6262.

111.Hu, X.-J.; He, H.-P.; Zhou, H.; Di, Y.-T.; Yang, X.-W.; Hao, X.-J.; Kong, L.-Y., New indole alkaloids from Rauvolfia yunnanensis. Helv. Chim. Acta 2006, 89, 1344?1350.

112.Di, Y.-T.; He, H.-P.; Lu, Y.; Yi, P.; Li, L.; Wu, L.; Hao, X.-J., Alkaloids from the Leaves of Daphniphyllum longeracemosum. J. Nat. Prod. 2006, 69, 1074?1076.

113.Di, Y.-T.; He, H.-P.; Liu, H.-Y.; Du, Z.-Z.; Tian, J.-M.; Yang, X.-W.; Wang, Y.-H.; Hao, X.-J., Calycilactone A, a novel hexacyclic alkaloid from Daphniphyllum calycillum. TetrahedronLett. 2006, 47, 5329?5331.

114.Di, Y.-T.; He, H.-P.; Li, C.-S.; Tian, J.-M.; Mu, S.-Z.; Li, S.-L.; Gao, S.; Hao, X.-J., Yuzurimine-Type Alkaloids from Daphniphyllum yunnanense. J. Nat. Prod. 2006, 69, 1745?1748.

115.Zhou, H.; He, H.-P.; Luo, X.-D.; Wang, Y.-H.; Yang, X.-W.; Di, Y.-T.; Hao, X.-J., Three new indole alkaloids from the leaves of Alstonia scholaris. Helv. Chim. Acta 2005, 88, 2508?2512.

116.Dou, H.; Di, Y.-T.;Ding, L., Research progress on the cyclotides from plant kingdom. Tianran Chanwu Yanjiu Yu Kaifa 2004, 16, 76?79.

117.Zhu, X.; Di, Y.-T.;Peng, S.; Wang, M.; Ding, L., Chemical constituents from root of Glycyrrhiza uralensis. Zhongcaoyao 2003, 34, 198?201.

118.Di, Y.-T.;T.; Liao, X.; Peng, S. L.; Liang, J.; Ding, L. S., A novel monoterpene glycoside from Swertia mileensis. Chin. Chem. Lett. 2003, 14, 1154。
承担科研项目情况:
1、云南省重点基金项目, 2015/03-2018/04,50万元,在执行,主持;

2、西部之光一般项目,2014/03-2017/03,30万,在执行,主持;

3、国家重点实验室自主课题,2015/01-2015/12,20万,在执行,主持;

4、国家自然科学基金重点项目,2015/01-2019/06,350万,参加;

5、 云南省学术与技术带头人项目,6万,2015/01-2017/12,6万,主持。
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