d_xy@tju.edu.cn
生物化工
归国留学人员
教授
淀粉质β多肽聚集的亲和纳米抑制剂的设计和作用机理研究

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氧化还原折叠酶模拟物的分子设计和作用机理研究

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淀粉样多肽聚集的抑制机理及抑制剂的理性设计

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基因重组蛋白质药物高效复性技术研究

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新一代生物催化和生物转化的科学基础

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淀粉质β多肽自结合作用及其作用机理研究

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金属螯合亲和反胶团的构建和蛋白质分离复性研究

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亲和性肽配基组合文库的理性设计和筛选
制备型横向电场的体积排阻电色谱分离生物大分子的方法

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横向电场提高离子交换吸附剂动态吸附容量的方法

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以碳酸钙微粒悬浮液制备超大孔型刚性高分子介质的方法

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用于抑制β淀粉样蛋白聚集的多肽和多肽功能化的金纳米粒子及制备和应用，中国发明专利

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聚乙烯醇涂层毛细管的制备方法及应用，中国发明专利，申请号：

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一种金属螯合纳米介质及制备方法和应用于强化包涵体蛋白复性与集成纯化的方法, 中国发明专利，

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超大孔纤维素微球蛋白质吸附介质的制备方法，中国发明专利，0.X

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开发了用于抑制β淀粉样蛋白聚集的多肽和多肽功能化的金纳米粒子的制备方法

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开发了一种金属螯合纳米介质的制备方法，并将其应用于强化包涵体蛋白复性与集成纯化

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Interactions between L-arginine/L-arginine derivatives and lysozyme and implications to their inhibition effects on protein a

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Characterization of new polymer-grafted protein cation exchangers developed by partial neutralization of carboxyl groups der

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Charge effects of self-assembled chitosan-hyaluronic acid nanogels on inhibiting amyloid β-protein aggregation

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RTHLVFFARK-NH2: A potent and selective modulator on Cu2+-mediated amyloid-β protein aggregation and cytotoxicity

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Implications from protein adsorption onto anion- and cation-exchangers derivatized by modification of poly(ethylenimine)-Seph

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Head-to-tail cyclization of LVFFARK eliminates its cytotoxicity and significantly increases its inhibition effect on amyloid

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Design of molecular hybrid of dual peptide inhibitors conjugated onto AuNPs for enhanced inhibition of amyloid β-protein aggr

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Grafting metal chelator on silica nanoparticles for facilitated refolding of like-charged protein and its metal-chelate affin

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Hematoxylin inhibits amyloid β-protein fibrillation and alleviates amyloid-induced cytotoxicity

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Ac-LVFFARK-NH2 conjugation to β-cyclodextrin exhibits significantly enhanced performance on inhibiting amyloid β-protein fibr

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姜黄素修饰透明质酸的自组装特性及其对Aβ40聚集的抑制作用

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Modulation effect of acidulated human serum albumin on Cu2+-mediated amyloid β-protein aggregation and cytotoxicity under a m

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Nanogels of dual inhibitor-modified hyaluronic acid function as a potent inhibitor of amyloid β-protein aggregation and cytot

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Dual effect of thioflavin T on the nucleation kinetics of amyloid β-protein 40

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Grafting metal chelator on silica nanoparticles for facilitatedrefolding of like-chargedprotein and its metal-chelate affinit

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Mechanistic studies of protein refolding facilitated by like-charged polymers.

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A metal-chelate affinity reverse micellar system for protein extraction.

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A double-modification strategy for enhancing charge density of mono-sized beads for facilitated refolding of like-charged pro

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Atomistic characterization of binding modes and affinity of peptide inhibitors to amyloid-β protein.

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Dual effect of thioflavin T on the nucleation kinetics of amyloid β-protein 40

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Hematoxylin inhibits amyloid β-protein fibrillation and alleviates amyloid-induced cytotoxicity.

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Design of a Molecular Hybrid of Dual Peptide Inhibitors Coupled on AuNPs for Enhanced Inhibition of Amyloid β-Protein Aggrega

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Grafting metal chelator on silica nanoparticles for facilitatedrefolding of like-chargedprotein and its metal-chelate affinit

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Enhanced Protein Adsorption and Facilitated Refolding of Lik-Charged Protein with Highly Charged Silica Nanoparticles Fabrica

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Multifunctionality of self-assembled nanogels of curcumin-hyaluronic acid conjugates on inhibiting amyloid β-protein fibrilla

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Integrative refolding and purification of histidine-tagged protein bylike-charge facilitated refolding and metal-chelate aff

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Sequential tentacle grafting and charge modification for enhancing charge density of mono-sized beads for facilitated protein

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Refolding of recombinant homodimeric malate dehydrogenase expressed in Escherichia coli as inclusion bodies.