姓名 杨晓英
职称
教授
所在部门
药学院
研究方向
纳米材料
有机化学


办公室
药学院B楼202
办公电话
**
电子邮箱
yangxiaoying@tmu.edu.cn

教育背景

1988.9–1992.7，南开大学，化学专业，本科
1999.9–2002.7，南开大学，高分子化学与物理专业，硕士
2003.9–2006.7，南开大学，高分子化学与物理专业，博士
2010.1-2012.12，天津医科大学，博士后

工作经历

2013.11-至今，天津医科大学，药学院，教授
2008.11-2013.10，天津医科大学，药学院，副教授
1998.11-2008.10，天津医科大学，药学院，讲师
1992.7-1998.10，天津医科大学，药学院，助教

研究成果（本人具有代表性的论著、论文及主持的科研项目）

论著及编著

参编专著：石墨烯－新型二维碳纳米材料，科学出版社，2013年6月第一版

论文

1.Beibei Wang, Sunyi Wu, Zhiqiang Lin, Yajun Jiang, Yan Chen, Zhe-Sheng Chen, Xiaoying Yang*, Wei Gao*. A personalized and long-acting local therapeutic platform combining photothermal therapy and chemotherapy for the treatment of multidrug-resistant colon tumor. International Journal of Nanomedicine, 2018, 13, 8411-8427.
2. Qianyu Zhang, Li Wang, Yajun Jiang, Wei Gao, Yinsong Wang, Xiaoying Yang*, Xinlin Yang, Zunfeng Liu*. Gold nanorods with silica shell and PAMAM dendrimers for efficient photothermal therapy and low toxic codelivery of anticancer drug and siRNA. Advanced Materials Interfaces, 2017，4(24),** (1-9).
3.Xinghua Liu, Chunhui Gao, Junheng Gu, Yunfang Jiang, Xinlin Yang, Shaoyong Li, Wei Gao, Tong An, Hongquan Duan, Jingwei Fu, Yinsong Wang*, Xiaoying Yang*. Hyaluronic acid stabilized iodine-containing nanoparticles with Au nanoshell coating for X?ray CT imaging and photothermal therapy of tumors.ACS Applied Materials & Interfaces, 2016, 8(41), 27622-27631.
4. Yunfang Jiang, Qianyu Zhang, Xinghua Liu, Yifu Chen, Li Wang, Jingwei Fu, Hongquan Duan, Yinsong Wang, Xiaoying Yang*. Au nanoshell-coated superparamagnetic Fe₃O₄–silica composite nanoparticles with surface modification of an activatable cell-penetrating peptide for tumor-targeted multimode bioimaging and photothermal therapy. RSC advances,2016, 6(88), 85587-85594.
5.Yunfang Jiang, Xinghua Liu, Jing Li, Lei Zhou, Xiaoying Yang*, Yi Huang*. Enhanced electrochemical oxidation of p-nitrophenol using single-walled carbon nanotubes/silver nanowires hybrids modified electrodes. Journal of Nanoscience and Nanotechnology,2015, 15, 6078-6081.
6. Xiufen Cao, Shuang Zheng, Sipei Zhang, Yinsong Wang, Xiaoying Yang*, Hongquan Duan, Yi Huang*, and Yongsheng Chen. Functionalized graphene oxide with hepatocyte targeting as anti-tumor drug and gene intracellular transporters.Journal of Nanoscience and Nanotechnology, 2015, 15, 2052-2059.
7. Fuli Feng, Rongrong Li, Qingyun Zhang, Yinsong Wang, Xiaoying Yang*, Hongquan Duan, Xinlin Yang*. Preparation of reduction-triggered degradable microcapsules for intracellular delivery of anti-cancer drug and gene. Polymer, 2014, 55, 110-118.
8.Rongrong Li, Fuli Feng, Yinsong Wang, Xiaoying Yang*, Xinlin Yang*, Victor C. Yang. Folic acid-conjugated pH/temperature/redox multi-stimuli responsive polymer microspheres for delivery of anti-cancer drug. Journal of Colloid and Interface Science, 2014, 429, 34-44.
9.Xiufen Cao, Fuli, Feng, Yinsong Wang, Xiaoying Yang*, Hongquan Duan, Yongsheng Chen. Folic acid-conjugated graphene oxide as a transporter of chemotherapeutic drug and siRNA for reversal of cancer drug resistance. Journal of Nanoparticle Research, 2013, 15, 1965-1976.
10.Xiaoying Yang,*,Gaoli Niu, Xiufen Cao, Yuku Wen, Rong Xiang,* Hongquan Duan and Yongsheng Chen*. The preparation of functionalized graphene oxide for targeted intracellular delivery of siRNA.Journal of Materials Chemistry,2012, 22, 6649-6654.
11.Xiaoying Yang*, Yinsong Wang, Xin Huang, Yanfeng Ma, Yi Huang, Rongcun Yang, Hongquan Duan and Yongsheng Chen*. Multi-functionalized graphene oxide based anticancer drug-carrier with dual-targeting function and pH-sensitivity. Journal of Materials Chemistry,2011, 21, 3448-3454.
12.Xiaoying Yang*, Lei Chen, Bin Han, Xinlin Yang*, Hongquan Duan. Preparation of magnetite and tumor dual-targeting hollow polymer microspheres with pH-sensitivity for anticancer drug-carriers. Polymer,2010, 51, 2533-2539
13.Xiaoying Yang*, Xiaoyan Zhang, Yanfeng Ma, Yi Huang,Yinsong Wang, Yongsheng Chen*, Superparamagnetic graphene oxide–Fe₃O₄nanoparticles hybrid for controlled targeted drug carriers. Journal of Materials Chemistry,2009,19, 2710–2714.
14.Xiaoying Yang*, Liting Chen, Bo Huang, Feng Bai, Xinlin Yang*. Synthesis of pH-Sensitive Hollow Polymer Microspheres and Their Application as Drug Carriers”. Polymer, 2009, 50, 3556–3563.
15.Xiaoying Yang*, Xiaoyan Zhang, Zunfeng Liu, Yanfeng Ma, Yi Huang,Yongsheng Chen*, High-efficiency loading and controlled release of doxorubicin hydrochloride on graphene oxide. Journal ofPhysical Chemistry C2008, 112, 17554–17558.
16.Xiaoying Yang*, Zhuohan Zhang, Zunfeng Liu, Yanfeng Ma, Rongcun Yang, Yongsheng Chen*. Multi-functionalized single-walled carbon nanotubes as tumor cell targeting biological transporters. Journal of Nanopartcle Research, 2008, 10, 815–822.

科研项目

1.天津市应用基础与前沿技术研究计划（重点项目）（No. 15JCZDJC36300）：可激活穿膜肽介导的CT对比剂用于肿瘤靶向成像的研究（2015.04-2018.03），20万，主持人。
2.国家自然科学基金青年科学基金（No. **）：基于氧化石墨烯的肝靶向小干扰RNA和抗肿瘤药物共载输送体系的研究（2012.01-2014.12），25万，主持人。
3.博士后基金特别资助（No. ）：基于逆转肝癌多药耐药的小干扰RNA和抗肿瘤药物共载输送体系的研究（2011.10-2013.10），10万，主持人。
4.博士后基金面上一级资助（No. ）：基于多功能单层氧化石墨的靶向性基因载体的制备（2010.12-2012.12），5万，主持人。
5.天津市高等学校科技发展基金计划项目（No. **）：基于多功能新型碳纳米材料的靶向性抗肿瘤药物载体（2009.12-2012.11），3万，主持人。
6.天津市应用基础及前沿技术研究计划（No. 07JCYBJC01700）：基于单壁碳纳米管的肝靶向性抗癌药物载体的研究（2007.04-2009.09），8万，主持人。
7.横向课题：碳纳米管与生物复合传感器制备技术的研发（2012.11-2014.10），13万，主持人。

荣誉奖励

天津医科大学十一五新世纪人才