姓名
靳美娜
职称
讲师
所在部门
药学院
研究方向
天然产物抗糖尿病作用机制研究

办公室
基础医学研究心702
办公电话
**
电子邮箱
jinmeina@tmu.edu.cn

教育背景

本科 2004.9-2008.9 天津医科大学 药物制剂
博士 2008.9-2013.7 天津医科大学/日本德岛大学 药理学

工作经历

2013.7-今 天津医科大学药学院 讲师

研究成果（本人具有代表性的论著、论文及主持的科研项目）

论文

1.Gan CC, Ni TW, Yu Y, Qin N, Chen Y, Jin MN*, Duan HQ**, Flavonoid derivative (Fla-CN) inhibited adipocyte differentiation via activating AMPK and up-regulating microRNA-27 in 3T3-L1 cells, European Journal of Pharmacology, 2017, 797: 45-52.
2.Jin MN, Yao Z, Takaishi Y, Duan HQ*. Lignans from schisandra proinqua with inhibitory effects on lymphocyte proliferation. Plant Medica, 2012, 78, 807-813.
3.Jin MN, Ma SN, Zhai HY, Kong D*, Duan HQ*. A new megastigmane alkaloid from Pachysandra terminalis with antitumor metastasis effect. Chemistry of Natural Compounds, 2015, 51(2): 311-315.
4.Jin MN1, Shi GR1, Tang SA, Qin N, Qiao W, Duan HQ*. Flavonoids from Tetrastigma obtectum enhancing the glucose consumption in insulin-resistance HepG2 cells via activating AMPK, Fitoterapia, 2013, 90:240-246.
5.Chen Y, Zhang C, Jin MN, Qin N, Qiao W, Yue XL, Duan HQ*, Niu WY*. Flavonoid derivative exerts an antidiabetic effect via AMPK activation in diet-induced obesity mice. Nat Prod Res. 2016, 30(17): 1988-92.
6.Qin N,Chen Y,Jin MN,Zhang C,Qiao W,Yue XL,Duan HQ*,Niu WY*. Anti-obesity and anti-diabetic effects of flavonoid derivative (Fla-CN) via microRNA in high fat diet induced obesity mice. Eur J Pharm Sci.2016, 82, 52-63.
7.Qin N, Jia M, Wu XR, Shou XA, Liu Q, Gan CC, Jin MN, Yu Y, Duan HQ*. Synthesis and anti-metastatic effects of pregn-17(20)-en-3-amine derivatives, Eur J Med Chem, 2016,124:490-499.
8.Gao F, Zhai HY, Jin MN, Chu GB, Duan HQ, Li CB*. A New Synthesis of Cytotoxic Thiosulfonates and the First Synthesis of Deuterated Thiosulfonates.Synthesis-Stuttgart, 2011, 22, 3635-3638.
9.Qin N, Li CB, Jin MN, Shi LH, Duan HQ*, Niu WY*. Synthesis and biological activity of novel tiliroside derivants.European Journal of Medicinal Chemistry, 2011, 46, 5189-5195.
10.Li BL, Shen Q, Jin MN, Duan HQ*. Two new terpenes from Tripterygium wilfordii.Chinese Chemical Letters, 2010, 21, 827-829.
11.Chang LS, Li CB, Qin N, Jin MN, Duan HQ*. Synthesis and Antidiabetic Activity of 5,7-Dihydroxyflavonoids and Analogs. Chemistry & biodiversity, 2012, 9,162-169.

科研项目

2014.9-2017.9 天津教委项目 黄酮衍生物QN203靶向miRs调控脂代谢作用机制研究
2018.4-2021.3 天津市自然科学基金 多靶点介导的Tiliroside衍生物调控脂代谢协同机制的体外研究


荣誉奖励

2016.6 天津医科大学第十三届青年教师教学基本功竞赛三等奖
2016.12 天津医科大学优秀班导师
2017 天津医科大学工会积极分子
2018.1 天津医科大学第十四届青年教师教学基本功竞赛基础组三等奖