姓　　名
黄有 性　　别
男
出生年月
1962-10 籍　　贯
河南洛阳栾川县
学　　历
博士毕业院校
浙江大学
职　　称
教授管理职务

学科专业
有机化学 系所单位
元素有机化学研究所
特殊人才称号

通讯地址
南开大学元素所
电话
**
电子邮件
hyou@nankai.edu.cn
课题组网站
http://skleoc.nankai.edu.cn/professors/huangy/huangyou.htm
研究领域
研究方向：
1.有机磷化学
2.有机合成化学
3.杂原子有机化学

在研项目：
1.有机膦催化的分子间连续环化Domino反应构筑双环 [m. n. 0]骨架
国家自然科学基金(**)
2015.1-2018.12
2.有机膦小分子催化的活泼共轭二烯基于Rauhut-Currier反应的串联反应研究
国家自然科学基金（**）
2012.1-2015.12
3.有机膦小分子催化的基于β，γ-不饱和α 酮酸酯Domino 反应研究
博士点基金（**002）
2013.1-2015.12
4.有机膦催化的多环体系的高效构筑方法研究
天津市自然科学基金 (15JCYBJC20000)
2015.4-2018.3
教育及科研经历
Education:
1982-1986年 河南师范大学化学系 本科
1986-1989年 河南师范大学化学系 硕士研究生
1994-1997年 浙江大学化学系 博士研究生
1989-1994年 河南师范大学化学系 助教、讲师
1997-1999年 南开大学元素所 博士后
1999-2002年 大阪大学药学院 博士后
2002-2008年 南开大学化学院 副教授
2008-2011年 南开大学化学院 教授
2011年至今 南开大学化学院 教授，博士生导师
荣誉和奖励
2004年，获南开大学敬业奖教金教学二等奖
2013年，获南开大学敬业奖教金教学二等奖
2013年，获南开大学校级“教工先锋岗”先进个人
2013年，获南开大学第五届“良师益友”提名奖

科研成果与代表作
代表性论文：

1. DABCO-Mediated [4 + 4]-Domino Annulation: Access to Functionalized Eight-Membered Cyclic Ethers
Liang, Ling; Li, Erqing; Dong, Xuelin; Huang You
Org. Lett.2015, 17(19), 4914?4917.

2. Highly Enantioselective Intermolecular Cross Rauhut–Currier Reaction Catalyzed by a Multifunctional Lewis Base Catalyst
Dong, Xuelin; Liang, Ling; Li, Erqing and Huang You
Angew. Chem. Int. Ed. 2015, 54, 1621-1624. （Hot Paper）

3.Divergent Phosphine-Catalyzed [2+4] or [3+2] Cycloaddition Reactions ofγ-Substituted Allenoates with Oxadienes
Li, Erqing; Chang, Meijia; Liang, Ling and Huang You
Eur. J. Org. Chem. 2015, 710–714. （Hot Paper)

4. Morita–Baylis–Hillman adduct derivatives (MBHADs): versatile reactivity in Lewis base-promoted annulation
Xie, Peizhong and Huang You
Org. Biomol. Chem. 2015, 13(32), 8578–8595

5.A Sulfur Ylides-Mediated Domino Benzannulation Strategy to Construct Biaryls, Alkenylated and Alkynylated Benzene Derivatives
Gao Fei and Huang, You
Adv. Synth. Catal. 2014, 356, 2422-2428.

6Phosphine-catalyzed Domino Reaction: A Novel Sequential [2+3] and [3+2] Annulation Reaction of γ-Substituent Allenoates to Construct Bicyclic[3, 3, 0]octene Derivatives.
Li, Erqing; Huang, You*
Chem. Commun., 2014, 50 (8), 948-950.

7 Sequential Catalyst Phosphine/Secondary Amine-Promoted [1+4]/ Rearrangement Domino Reaction for the Construction of (2H)-Pyrans and 2-oxabicyclo[2.2.2]oct-5-ene Skeletons
Xie, Peizhong; Yang, Jie; Zheng, Jie; Huang, You*
Eur. J. Org. Chem., 2014, 1189-1194.

8 Phosphine-Catalyzed Domino Reaction: A Novel Method Access to Functionalized
Bicyclic Skeletons
Li, Erqing; Huang, You*
Chem. Eur. J., 2014, 20, 3520

9Phosphine Initiated Domino Reaction: A Convenient Method for the Preparation of Spiro-cyclopentanones
Liang, Ling; Li, Erqing; Xie, Peizhong; Huang You*
Chem. Asian J. 2014, 9(5), 1270-1273

10 Phosphine-Catalyzed Sequential [2 +3] and [3 + 2] Annulation Domino Reaction of γ- Benzyl Substituted Allenoates with α,β-Unsaturated Ketimines To Construct Aza-bicyclo[3, 3, 0]octane Derivatives
Li, Erqing; Jia, Penghao; Liang, Ling; Huang, You*
ACS Catal. 2014, 4, 600?603.

11A simple and highly efficient procedure for construction of quaternary carbons centers by tributylphosphine catalyzed bis-Michael addition
Xu, Da-Zen; Zhan, Ming-Zhe; Huang, You*
Tetrahedron 2014, 70, 176-180

12. One step Synthesis of Benzoxazepine Derivatives via a PPh3 Catalyze aza-MBH Domino Reaction between Salicyl N-tosylimines and Allenoates.
Zhao, Hongxia; Meng, Xiangtai; Huang, You*
Chem. Commun., 2013, 49(89), 10513-10515.
(Highlighted by Prof. Snieckus, V and Guimar?es, K. G. in Synfacts 2014, 10(1), 0027)

13. Phosphine-Catalyzed Domino Reaction: An Efficient Method for the Synthesis of Bicyclo[3.2.0]heptenes Skeleton.
Zheng, Jie; Huang, You*; Li, Zhengming
Org. Lett. 2013, 15(22), 5758-5761.

14. Phosphine-Catalyzed Domino Benzannulation: An Efficient Method to Construct Biaryl Skeletons.
Zheng, Jie; Huang, You*; Li, Zhengming
Org. Lett. 2013,15(19), 5064-5067.

15.Phosphine-Catalyzed [4+2] Annulation of gamma-Substituent Allenoates: Facile Access to
Functionalized Spirocyclic Skeletons.
Li, Erqing; Huang, You*; Liang, Ling; Xie Peizhong
Org. Lett. 2013,15(12), 3138-3141.

16. Tunable Phosphine-Mediated Domino Reaction: Selective Synthesis of 2,3-Dihydrofurans and Biaryls
Xie, Peizhong; Li, Erqing; Zheng, Jie; Li, Xin; Huang, You*; Chen, Ruyu
Adv. Synth. Catal. 2013, 355(1), 161 – 169. （Hot Paper)

17. Tuning Catalysts to Tune the Products: Phosphine-Catalyzed Aza-Michael Addition Reaction of Hydrazones with Allenoates.
Li, Erqing; Xie, Peizhong; Yang, Lihua, Liang Ling, Huang You*.
Chem. Asian J. 2013, 8(3) , 603-610.

18. Phosphine-Catalyzed Rauhut-Currier Domino Reaction: A Facile Strategy for the Construction of Carbocyclic Spirooxindoles Skeletons
Hu, Chongchong; Zhang, Qinglong; Huang, You*
Chem. Asian J. 2013, 8(9) , 1981-1984

19. Domino Cyclization Initiated by Cross-Rauhut-Currier Reactions
Xie, Peizhong; Huang, You*
Eur. J. Org. Chem. 2013, (20), 6213–6226.
20. Sulfur Ylides Participating Domino Cyclization Reaction.
Li Gongchun; Wang Liye; Huang You*
Chin. J. Chem. 2013, 33(9), 1900-1918.

21. Phosphine-catalyzed Domino Reaction: an Efficient Method for the Synthesis of Highly Functionalized Spirooxazolines.
Yang, Lihua; Xie, Peizhong; Li, Erqing; Li, Xin; Huang, You*; Chen, Ruyu
Org. Biomol. Chem. 2012, 10(37), 7628-7634.

22. Phosphine-Catalyzed Rauhut-Currier Domino Reaction: A Facile Strategy for the Construction of Highly Functionalized Cyclopentene.
Hu, Chongchong; Geng, Zhishuai; Ma, Jianze; Huang, You*; Chen, Ruyu
Chem. Asian J. 2012, 7(9) , 2032-2035.

23.Phosphine-mediated Domino Benzannulation Strategy for the Construction of Highly Functionally Multi-aryl Skeletons
Xie, Peizhong; Huang, You*; Chen, Ruyu
Chem. Eur. J. 2012, 18(24), 7362-7366 (Mostaccessed article 2012.5)
24. Phosphine-Catalyzed Domino Reaction for the Synthesis of Conjugated 2,3-Dihydrofurans from Allenoates and Nazarov Reagents and the Mechanism Investigation
Xie, Peizhong; Lai, Wenqing; Geng Zhishuai; Huang, You*; Chen, Ruyu
Chem. Asian J. 2012, 7(7) , 1533-1537

25. Bifunctional phosphine-catalyzed Cross-Rauhut-Currier/Michael/Aldol Condensation Triple Domino Reaction: Synthesis of Functionalized cyclohexenes.
Xie, Peizhong; Huang, You*; Lai, Wenqing; Meng, Xiangtai; Chen, Ruyu.
Org. Biomol. Chem. 2011, 9(19), 6707-6714.

26. Domino Reaction for the Chemo- and Stereoselective Synthesis of Trans-2,3-Dihydrobenzofurans from N-Thiophosphinyl Iimines and Sulfur Ylides.
Xie, Peizhong; Wang, Liye; Yang, Lihua; Li, Erqing; Ma, Jianze; Huang, You*; Chen, Ruyu.
J. Org. Chem. 2011, 76(19), 7699-7705

27.Substrate-Controlled Phosphine-Catalyzed Domino Reactions of Activated Conjugated Dienes: HighlyDiastereoselective Synthesis of Bicyclic Skeletons.
Ma, Jianze; Xie, Peizhong; Hu, Chongchong; Huang, You*; Chen, Ruyu.
Chem. Eur. J. 2011, 17(27), 7418-7422 （Hot Paper)

28. N-Heterocyclic Carbene-Catalyzed (NHC) Three-Component Domino Reactions: Highly
StereoselectiveSynthesis of Functionalized Acyclic ε-Ketoesters.
Ma, Jianze; Huang, You*; Chen, Ruyu.
Org. Biomol. Chem. 2011, 9(6), 1791-1798

29.Phosphine-Catalyzed Domino Reaction: Highly StereoselectiveSsynthesis of Trans-2,3-Dihydrobenzofuransfrom SalicylN-Thiophosphinyl Imines and Allylic Carbonates.
Xie, Peizhong; Huang, You*; Chen, Ruyu.
Org Lett. 2010, 12(17), 3768-3771.

30. PPh3-Catalyzed Domino Reaction: A Facile Method for theSynthesis of Chroman Derivatives.
Meng, Xiangtai; Huang, You*; Zhao, Hongxia; Xie, Peizhong; Ma, Jianze; Chen, Ruyu.
Org. Lett. 2009, 11(4), 991-994.

31. Bifunctional Phosphine-Catalyzed Domino Reaction: Highly Stereoselective Synthesis of cis-2,3-Dihydrobenzofuransfrom Salicyl N-Thiophosphinyl Imines and Allenes.
Meng, Xiangtai; Huang, You*; Chen, Ruyu.
Org Lett. 2009, 11(1), 137-140.

32. A Novel Selective aza-Morita-Baylis-Hillman (aza-MBH)Domino Reaction and aza-MBH Reaction of N-Sulfonated Imines with Acrolein Catalyzed by a Bifunctional Phosphine Organocatalyst.
Meng, Xiangtai; Huang, You*; Chen, Ruyu.
Chem. Eur. J. 2008, 14(23), 6852-6856.（Hot Paper， Most accessed article 2008.7)
人才培养
已培养博士生5名，硕士生16名，在读博士生3名，硕士生6名。

在读博士研究生： 梁玲，张庆龙，贾鹏昊
在读硕士研究生： 常美佳， 金红星， 吴成洲，冯佳旭， 陈俊龙， 殷仲墨
在读本科生：李宁

已毕业研究生：

博士：孟祥太（2009）解沛忠（2013）郑洁（2014） 李二庆（2015） 董雪林（2015）

硕士：冯德鑫（2004）谷迎春、王金亮（2006）于雅琴（2007）徐大振（2008）张葵、崔萌（2009）赵红霞、邵永臣（2010）马俭泽、熊琴平（2011）王利叶、杨丽华（2012） 胡冲冲（2013）高飞（2014）杨杰（2015）

本科生：徐大振（2004）潘璐，邹官军（2005）赵红霞（2006）韩百亮，何东明（2007）刘堂林（2008）来文庆，陈羽琛（2010）耿志帅（2012）陈凯宏（2013）郑彦明（2015）

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