姓　　名
柳凌艳 性　　别
女
出生年月
1978-12 籍　　贯
湖北荆州仙桃市
学　　历
博士毕业院校
南开大学
职　　称
副研究员管理职务

学科专业
有机化学 系所单位
元素有机化学研究所
特殊人才称号

通讯地址
天津市卫津路94号南开大学元素有机化学研究所221室
电话
**
电子邮件
liulingyan@nankai.edu.cn
课题组网站

研究领域
研究领域：
1. 基于简单的高炔丙基胺的相关串联反应研究
2. 1,5-烯炔醇的环化异构化反应研究
3. 有机小分子催化的不对称反应研究
4. 功能性和刺激响应性高分子聚合物的设计、合成与表征及形态或催化性能研究


教育及科研经历
1996-2000武汉市华中师范大学化学系本科
2001-2007南开大学元素有机化学研究所攻读博士研究生
2007-2011南开大学元素有机化学研究所讲师
2012-至今南开大学元素有机化学研究所副研究员
2014-2015美国威斯康星大学-麦迪逊分校访问学者


荣誉和奖励

科研成果与代表作
科研经费：

现正主持承担4项自然科学基金，国家自然科学基金青年基金1项，主任基金1项，天津市自然科学基金青年1项，中央高校基本科研业务费1项。近5年来，在国内外重要学术刊物上发表了论文20余篇。

论文成果:

(1)Xiaoxun Li, Hui Li, Wangze Song, Po-Sen Tseng, Lingyan Liu,* Ilia A. Guzei, and Weiping Tang*, Divergent Reactivity of Rhodium(I) Carbenes Derived from Indole Annulations, Angew. Chem. Int. Ed. 2015, 54, 12905-12908.

(2)Chan Wang, Kaimeng Huang, Junying Wang, Hongkai Wang, Lingyan Liu,* Weixing Chang, and Jing Li*, Synthesis of Tetrasubstituted Pyrroles from Homopropargylic Amines via aSonogashira Coupling/Intramolecular Hydroamination/Oxidation Sequence, Adv. Synth. Catal. 2015, 357, 2795-2802.

(3) Junying Wang, Kaimeng Huang, Lingyan Liu*, Weixing Chang, Jing Li*, Gold(I)-catalyzed cyclization ofo-(alkynyl)styrene ether mediated by MeOH for the construction of 2-aryl-1H-indene acetal, Tetrahedron Lett. 2015, 56, 2659–2663.

(4) Pingping Huang, Lingyan Liu,* Weixing Chang, and Jing Li* An Unexpected Double Diels–Alder Reaction of (E)-2-Bromo-4-aryl-1,3-pentadiene Involving [1,5]-Hydrogen Migration and HBr Elimination: Synthesis of Bicyclo[2.2.2]octene Derivatives, Chem. Asian J. 2015, 10, 548-552.

(5)Kaimeng Huang, Xiaona Ke, Hongkai Wang, Junying Wang, Chenchen Zhou, Xiufang Xu,* Lingyan Liu*, and Jing Li*, PtI2-catalyzed cyclization of 3-acyloxy-1,5-enynes with the elimination of HOAc and a benzyl shift: synthesis of unsymmetricalm-terphenyls, Org. Biomol. Chem., 2015, 13, 4486-4493.

(6) PingpingMiao, HongkaiWang, Lingyan Liu,* Weixing Chang, and Jing Li* Palladium-Catalyzed Highly Chemoselective Cascade CouplingCyclization of Allenol Derivatives and Aryl Halides for the Construction of Dihydrobenzofuranols or Chromanols and Indolinols, Asian J. Org. Chem. 2015, 4,1050-1054.

(7) Lingyan Liu,* Yunna Zhu, Kaimeng Huang, Bing Wang, Weixing Chang, Jing Li* Asymmetric Organocatalytic Quadruple Cascade Reaction of 2-Hydroxychalcone with Cinnamaldehyde for the Construction of Tetrahydro-6H-benzo[c]chromene Containing Five Stereocenters, Eur. J. Org. Chem. 2014, 4342-4350.

(8) Lingyan Liu,* Yan Zhang, Hua Zhang, Kaimeng Huang, Bo-xin Gao, Min Zou, Xin Zhou, Hongkai Wang and Jing Li*The metal tin promoted cascade reaction of ketone in aqueous media for the construction of 2-bromo-4-aryl-1,3-pentadiene, Org. Biomol. Chem., 2014, 12 (29), 5393-5399.

(9) Ling-yan Liu, Bing Wang, Yunna Zhu, Wei-xing Chang, Jing Li*, Additive-controlled Regioselectivity Direct Asymmetric Aldol Reaction of Hydroxyacetone and AldehydeTetrahedron: Asymmetry 2013, 24, 533-542.

(10) Lingyan Liu, Yunna Zhu, Kaimeng Huang, Weixing Chang, and Jing Li*, Organic Phosphine Based on L-proline Catalyzed Asymmetric Michael Addition of Cyclohexanone or Cyclopentanone to Chalcones, Eur. J. Org. Chem. 2013, 13, 2634-2645.

(11) Yong-Guang Jia, Jian Jiang, Ling-Yan Liu*, Wei-Xing Chang, Jing Li* Effect of Cross-Linker on Morphology, Catalytic Activity, and Recyclability of Immobilized Palladium Chloride, J. Appl. Polym. Sci. 2013, 128, 2604-2610.

(12) Yong-Guang Jia, Jian Jiang, Ling-Yan Liu*, Wei-Xing Chang, Jing Li Preparation and Characterization of Novel Organic/Inorganic Hybrid Nanoparticles Containing an Organotin Core and a Polystyrene Shell, J. Appl. Polym. Sci. 2012, 126: 56-65.

(13) Yong-guang Jia, X. X. Zhu*, Ling-yan Liu?, and Jing Li*, Multi-Responsive Properties of a Poly(Ethylene Glycol)-Grafted Alternating Copolymers of Distyrenic Monomer with Maleic Anhydride, Langmuir, 2012, 28 (9), 4500-4506.

(14) Feng, Gang; Jia, Yong-guang; Liu, Ling-yan*; Chang, Wei-xing; Li, Jing*, Well-defined polymers containing 1,3-dichloro-tetra-n-butyl-distannoxane moiety: Synthesis, mechanism, and applications in catalysis, J. Appl. Polym. Sci. 2012, 123, 3485-3494.

(15) Liu Ling-yan*, Zhang Yan, Huang Kai-meng, Chang Wei-xing, Jing Li*.1,3-Dichloro-tetra-n-butyl-distannoxane: a new application for catalyzing the direct substitution of 9 H-xanthen-9-ol at room temperature, Appl. Organometal. Chem. 2012, 26, 9-15.

(16) Jia, Yong-guang; Liu, Ling-yan; Lei, Bin; Li, Jing*; Zhu, X. X.*, Crown Ether Cavity-Containing Copolymers via Controlled Alternating Cyclocopolymerization Macromolecules 2011, 44, 6311-6317.

(17) Liu, Ling-yan; Wang, Bing; Yang, Hong-mei; Chang, Wei-xing; Li, Jing*, The direct substitutions of 9H-xanthen-9-ol with indoles in a room temperature ionic liquid medium BmimBF4, Tetrahedron Lett. 2011, 52, 5636-5639.

18) Lei, Bin; Jiang, Jian; Jia, Yong-guang; Liu, Ling-yan*; Chang, Wei-xing; Li, Jing*, Novel organotin-containing diblock copolymer with tunable nanostructures: Synthesis, self-assembly and morphological change, J. Organometal. Chem. 2011, 696, 1416-1424.

(19) Feng, Gang; Jia, Yong-guang; Liu, Ling-yan*; Chang, Wei-xing; Li, Jing*, Novel organotin-containing shell-cross-linked knedel and core-cross-linked knedel: Synthesis and application in catalysis, J. Polym. Sci. Part A: Polym. Chem. 2010, 48, 5992-6002.

(20) Wang, Xin; Liu, Ling-yan*; Chang, Wei-xing; Li, Jing*, Sequential Sonogashira/ Carbopalladative Cyclization/Suzuki Reactions Catalyzed by a Single Palladium Source by Using Protected Homopropargyl Alcohol, Eur.J. Org. Chem. 2010, 5391-5396.

(21) Wang, Bing; Liu, Xin-wang; Liu, Ling-yan*; Chang, Wei-xing; Li, Jing*, Highly Efficient Direct Asymmetric Aldol Reactions Catalyzed by a Prolinethioamide Derivative in Aqueous Media, Eur.J. Org. Chem. 2010, 5951-5954.

(22) Chen, Guo-hong; Liu, Ling-yan*; Wei, Xiao-ning; Chang, Wei-xing; Li, Jing*, Asymmetric Allylation of Aldehydes Catalyzed by Simple Dual Small Organic Molecules: L-Proline and L-Prolinol, Chem. Lett. 2010, 39, 1013-1015.

(23) Chen, Guo-hong; Wang, Xin; Jin, Xiao-qian; Liu, Ling-yan*; Chang, Wei-xing; Li, Jing*, Allyltin tribromide: A versatile reagent involved in the ring-opening of epoxides,Sci. Chin. Series B: Chem. 2010, 53, 1294-1301.

(24) Lei, Bin; Jia, Yong-guang; Liu, Ling-yan*; Chang, Wei-xing; Li, Ling*, Synthesis and Crystal Structure of Novel Sn–O Clusters Generated from nBu2SnO and Esters, Chin. J. Struct. Chem. 2010, 29: 1373-1379.

(25) Wang, Bing; Chen, Guo-hong; Liu, Ling-yan*; Chang, Wei-xing; Li, Jing*, A Novel Proline-Valinol Thioamide Small Organic Molecule for a Highly Enantioselective Direct Aldol Reaction,Adv. Synth.& Catal. 2009, 351, 2441-2448.

(26) Wang, Xin; Liu, Ling-yan*; Chang, Wei-xing; Li, Jing*, Sonogashira coupling reaction of homopropargyl ether with aryl bromides and synthesis of 2,5-disubstituted 3-bromofurans, Sci. Chin. Series B: Chem. 2009, 52, 1314-1320.

(27) Wei, Xiao-ning; Liu, Ling-yan*; Wang, Bing; Chang, Wei-xing; Li, Jing*, In(OTf)3 catalyzed allylation reaction of imines with tetraallyltin Chin. Chem. Lett. 2009, 20: 40-43.

(28) Wei, Xiao-ning; Liu, Ling-yan*; Wang, Bing; Chang, Wei-xing; Li, Jing, Allylation Reaction of Simple Imines by Organotin Reagents, Acta. Chimica Sinica 2009, 67, 833-837.

(29) Wei, Xiao-ning; Liu, Ling-yan*; Yu, Lei; Chang, Wei-xing; Li, Jing*, New Binuclear Allyla ting Reagents for Allylation of Aromatic Aldehydes, Chem. J.Chin. Univ. 2008, 29, 767-771.

(30) Liu, Ling-yan; Sun, Jing; Liu, Nan; Chang, Wei-xing; Li, Jing, A structurally simple l-proline derivative promotes the asymmetric allylation of aldehydes with tribromoallyltin, Tetrahedron: Asymmetry 2007, 18, 710-716.

(31) Liu, Ling-yan; Tang, Long; Yu, Lei; Chang, Wei-xing; Li, Jing, Indium triflate catalyzed allylation of ketones with diallyldibutyltin, Tetrahedron 2005, 61, 10930-10934.
人才培养
现有2名硕士研究生，曾经指导本科生白项工程2项，指导本科生毕业论文6名，并协助指导数十名博士和硕士研究生

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