梁玲利，博士，副教授，硕士/博士生导师。基础医学院青年学术委员会委员兼秘书。中国神经科学学会神经内稳态和内分泌分会委员。
Lingli Liang, Ph.D., Associate professor in the Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi’an Jiaotong University Health Science Center. Member and secretary of youth committee of School of Basic Medical Sciences and member of Neurohomeostasis and Endocrinology branch of Chinese society of neuroscience.
Contact information:
E-mail: ll2017@xjtu.edu.cn
Personal homepage：http://gr.xjtu.edu.cn/web/ll2017/home
Researchgate：https://www.researchgate.net/profile/Lingli_Liang
Addresses：
1. Science and Education Building 807, Yanta Campus, Xi'an Jiaotong University
西安交通大学雁塔校区科教楼807
2. Hongren Building 4024, Western China Science & Technology Innovation Harbour
中国西部创新港21号泓仁楼4024室

研究领域（方向）：
慢性疼痛的分子机制
Research interest: Molecular mechanisms of chronic pain.

教育经历：
1997-2002：郑州大学预防医学专业（B.A.）
2002-2005：上海中医药大学基础医学院中西医结合基础生物专业（M.S.）
2006-2010：复旦大学神经生物学研究所脑科学研究院神经生物学专业（Ph.D.）
Educations:
1997-2002: Bachelor Degree in Preventive Medicine/General Medicine from Zhengzhou University；
2002-2005: Master Degree in Cooperation of Chinese and Western medicine (Biology) from Shanghai University of Traditional Chinese Medicine；
2006-2010: PhD Degree in Neurobiology from Fudan University;

工作简介：
2017.9-至今：西安交通大学，副教授/博士生导师
2013.7-2017.8：美国新泽西罗格斯大学， Research associate
2010.6-2013.6：在美国约翰霍普金斯大学，博士后
2005.9-2006.9：上海中医药大学，助教
Work experiences:
2010-2013: Postdoctoral researcher at Johns Hopkins University;
2013-2017: Research associate in New Jersey Medical School, Rutgers University;
2017-present: Associate Professor in Xi’an Jiaotong University.

主要科研项目：
近年主持的科研项目：
1. 国家自然科学基金（面上项目，项目号**）
2. 国家自然科学基金（青年项目，项目号**）?
3. 陕西省自然科学基础研究计划一般项目（面上，2019JM-128，） ?
4. 中国博士后科学基金第63批面上资助（项目号：2018M633527）
5. 陕西省博士后项目资助（项目号：2018BSHEDZZ147）
6. 西安交通大学基本科研业务费自由探索（sxzy）
7. 西安交通大学“ 新教师科研支持计划”
Grants and fundings:
1. 2019.1-2022.12, National Natural Science Foundation of China (**)
2. 2018.1-2020.12, National Natural Science Foundation of China (**)
3. 2019.1.1-2020.12.31, Natural Science Foundation of Shaanxi Province (2019JM-128)
4. 2018.7.1-2020.6.30, China Postdoctoral Science Foundation (2018M633527)
5. 2018.7.1-2020.6.30, Postdoctoral Science Foundation of Shaanxi Province (2018BSHEDZZ147)
6. 2017.9.1-2020.12.31, Basic Science Foundation from Xi’an Jiaotong University
7. 2019.1.1-2021.12.31, Basic Science Foundation from Xi’an Jiaotong University (sxzy)

学术及科研成果、专利、论文：
在国内外杂志发表论文30余篇，包括国际著名期刊Nature communication、Neuron、Journal of Pain、Anesthesiology、Science signaling等。
More than 30 publications in domestic and foreign journals including Nature communication, Pain, Science signaling, Anesthesiology and other international journals.
Major publications in recent 5 years:
1) Liang L*,Wu S, Lin C, Chang YJ, Tao YX^#. Alternative splicing of Nrcam gene in dorsal root ganglion contributes to neuropathic pain. J Pain. 2020 Jan 6. pii: S1526-5900(19)30881-8.
2) Liang L*^#,Wei J, Tian L, Padma Nagendra BV, Gao F, Zhang J, Xu L, Wang H, Huo FQ. Paclitaxel Induces Sex-biased Behavioral Deficits and Changes in Gene Expression in Mouse Prefrontal Cortex. Neuroscience. 2020 Feb 1;426:168-178.
3) Liang L*^#,Zhang J^#, Tian L, Wang S, Xu L, Wang Y, Guo-Shuai Q, Dong Y, Chen Y, Jia H, Yang X, Yuan C. AXL signaling in primary sensory neurons contributes to chronic compression of dorsal root ganglion-induced neuropathic pain in rats. Mol Pain. 2020 Jan-Dec;16:**00814.
4) Shuo Wang*, Siyi Liu*, Linping Xu*, Xuan Zhu, Wanyuan Liu, Lixia Tian, Yu Chen, Yuying Wang, Borra. V. Padma Nagendra, Shushan Jia,,Lingli Liang^#, Fu-Quan Huo^#. The upregulation of EGFR in the dorsal root ganglion contributes to chronic compression of dorsal root ganglions-induced neuropathic pain in rats. Molecular Pain. Accepted. IF: 3.44.
5) Lingli Liang*,Jian-Yuan Zhao, Ticehurst Kathryn, Alex Bekker, Yuan-Xiang Tao. BIX01294, a G9a inhibitor, alleviates nerve injury-induced pain hypersensitivities during both development and maintenance periods. Transl Perioper Pain Med. 2019 ; 6(4): 106–114.
6) Lingli Liang*^#,Yuan-Xiang Tao. Expression of acetyl-histone H3 and acetyl-histone H4 in dorsal root ganglion and spinal dorsal horn in rat chronic pain models. Life sciences. 2018; 211:182-188. IF: 3.11.
7) Jian-Yuan Zhao*,Lingli Liang*,Xiyao Gu*, Zhisong Li*, Shaogen Wu, Linlin Sun, Fidelis E. Atianjoh, Jian Feng, Kai Mo, Shushan Jia, Brianna Marie Lutz, Alex Bekker, Eric J. Nestler, Yuan-Xiang Tao^#. DNA methyltransferase DNMT3a contributes to neuropathic pain by repressing Kcna2 in primary afferent neurons.Nature Communications.2017 Mar 8;8:14712. IF: 12.124.
8) Lingli Liang*,Jian-Yuan Zhao*, Xiyao Gu*, Shaogen Wu, Xuerong Miao, Kai Mo, Brianna Marie Lutz, Alex Bekker, Yuan-Xiang Tao^#. G9a participates in nerve injury-induced Kcna2 downregulation in primary sensory neurons. Scientific Reports. 2016 Nov 22; 6: 37704. IF: 4.259.
9) Lingli Liang*,Jian-Yuan Zhao, Xiyao Gu, Shaogen Wu, Kai Mo, Ming Xiong, Alex Bekker, Yuan-Xiang Tao^#. G9a inhibits CREB-triggered expression of mu opioid receptor in primary sensory neurons following peripheral nerve injury. Molecular pain. 2016 Dec 7;12: **82242. IF: 3.44.
10) Jun Zhang*,Lingli Liang*,Xuerong Miao*,Shaogen Wu, Jing Cao, Bo Tao, Qingxiang Mao, Kai Mo, Brianna Marie Lutz, Alex Bekker, Yuan-Xiang Tao^#. Contribution of the histone methyltransferase SUV39H1 in dorsal root ganglia and spinal cord dorsal horn to neuropathic pain. Anesthesiology. 2016 Oct; 125(4):765-78. IF: 5.66,Co-1^stauthor.
11) Zhisong Li*, Yuanyuan Mao*,Lingli Liang*, Shaogen Wu, Jingjing Yuan, Kai Mo, Weihua Cai, Qingxiang Mao, Jing Cao, Alex Bekker, Wei Zhang, Yuanxiang Tao^#. The transcription factor C/EBPβ in the dorsal root ganglion contributes to peripheral nerve trauma-induced nociceptive hypersensitivity. Science signaling. 2017 Jul 11;10(487). IF: 7.359.Co-1^stauthor.
12) Lingli Liang*, Brianna M. Lutz, Alex Bekker, Yuanxiang Tao#. Epigenetic regulation of chronic pain. Epigenomics. 2015;7(2):235-45. IF: 4.541. Cited by 6.
13) Linlin Sun*, Jian-Yuan Zhao*, Xiyao Gu*,Lingli Liang*, Shaogen Wu, Kai Mo, Jian Feng, Brianna Marie Lutz, Alex Bekker, Xinyu Zhao, Eric J Nestler, Yuan-Xiang Tao^#. Nerve injury-induced epigenetic silencing of opioid receptors controlled by DNMT3a in primary afferent neurons. Pain. 2017 Jun;158(6):1153-1165. IF: 5.445.Co-1^stauthor.
14) Lian Cui*, Xuerong Miao*,Lingli Liang, Ishmail Abdus-Saboor, Michael S Fleming, William Olson, Minghong Ma, Yuan-Xiang Tao^#, Wenqin Luo^#. Identification of Early RET+ Deep Dorsal Spinal Cord Interneurons in Gating Pain.Neuron. 2016 Sep 7; 91(5): 1137–1153. IF: 15.054.
15) Tiwari, Vinod; He, Shao-Qiu; Huang, Qian;Liang, Lingli;Yang, Fei; Chen, Zhiyong; Tiwari, Vineeta; Fujita, Wakako; Devi, Lakshmi A; Dong, Xinzhong; Guan, Yun; Raja, Srinivasa N. Activation of -delta opioid receptor heteromers inhibits neuropathic pain behavior in rodents. Pain. 2019 Dec 5. doi: 10.1097/j.pain.1768. [Epub ahead of print]
16) 朱璇;梁玲利; 贾树山.离子通道参与化疗痛外周机制的研究进展.神经解剖学杂志.2018,6:766-770.