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西安交通大学医学部基础医学院导师教师师资介绍简介-罗肖

本站小编 Free考研考试/2021-06-27


罗肖,博士,西安交通大学医学部生理学与病理生理学系 副教授,博士研究生导师。
2001-2005年就读于西北农林科技大学动物科学专业,获学士学位。2008年获生物学硕士学位。2011年获生物学博士学位。2009-2011年在澳大利亚昆士兰大学mater医学研究院做联合培养博士研究。2011年起在西安交通大学医学院生理教研室工作。兼任陕西省生理科学会理事、陕西省营养学会理事。
工作至今一直承担医学基础课程《生理学》、《机能实验学》和医学宗濂班PBL的教学工作。参编人民卫生出版社配套教材两部。
主要从事肥胖与糖尿病发病机制研究。发表学术论文20篇,其中在国际高水平学术期刊《Diabetes》、《FASEB journal》、《Mol Nutr Food Res》、《Mol Cell Endocrinol》、《Acta Physiologica》等发表论文40余篇。主持国家自然科学基金项2项,中国博士后基金一等1项,中国博士后特别资助1项,陕西省自然科学基金1项,陕西省博士后基金二等1项,中央高校基本科研业务项目2项。指导大学生创新实验项目8项。2015年获张锡钧基金会优秀论文奖。

研究方向:1.肥胖及糖尿病的发病机制;2.味觉生理学:摄食调控的神经-内分泌机制

招收硕士研究生学科
071000-01生理学
100104 病理学与病理生理学

招收博士研究生学科
071003生理学
100104病理学与病理生理学
招收各相关专业推免生(可跨一级学科)和博士后

联系电话:86--805
E-mail:xluo@mail.xjtu.edu.cn

代表性论文:
1. Wei, X., Jia, R., Wang, G., Hong, S., Song, L., Sun, B., Chen, K., Wang, N., Wang, Q.,Luo, X.*, and Yan, J.* (2020) Depot-specific regulation of NAD(+)/SIRTs metabolism identified in adipose tissue of mice in response to high-fat diet feeding or calorie restriction.J Nutr Biochem80, 108377
2. Wei, X., Jia, R., Yang, Z., Jiang, J., Huang, J., Yan, J., andLuo, X.* (2020) NAD(+) /Sirtuin metabolism is enhanced in response to cold-induced changes in lipid metabolism in mice liver.FEBS LettJun;594(11):1711-1725
3. Luo, X.,He, Z., Sun, X., Gu, X., Zhang, W., Gao, J., Li, X., Jia, R., Wei, J., Yu, Y., and Luo, X. (2020) DHA Protects Against Hepatic Steatosis by Activating Sirt1 in a High Fat Diet-Induced Nonalcoholic Fatty Liver Disease Mouse Model.Dibetes Metab Syndr Obes13, 185-196
4. Jia, R., Yi, Y., Liu, J., Pei, D., Hu, B., Hao, H., Wu, L., Wang, Z.,Luo, X.*, and Lu, Y.* (2020) Cyclic compression emerged dual effects on the osteogenic and osteoclastic status of LPS-induced inflammatory human periodontal ligament cells according to loading force.BMC Oral Health20, 7
5. Luo, X., Jia, R., Luo, X. Q., Wang, G., Zhang, Q. L., Qiao, H., Wang, N., and Yan, J. Q. (2017) Cold Exposure Differentially Stimulates Angiogenesis in BAT and WAT of Mice: Implication in Adrenergic Activation.Cell Physiol Biochem42, 974-986
6. Luo, X., Jia, R., Zhang, Q., Sun, B., and Yan, J. (2016) Cold-Induced Browning Dynamically Alters the Expression Profiles of Inflammatory Adipokines with Tissue Specificity in Mice.International journal of molecular sciences17, 14
7. Luo, X., Jia, R., Yao, Q., Xu, Y., Luo, Z., Luo, X., and Wang, N. (2016) Docosahexaenoic acid attenuates adipose tissue angiogenesis and insulin resistance in high fat diet-fed middle-aged mice via a sirt1-dependent mechanism.Mol Nutr Food Res60, 871-885
8. Jia, R., Luo, X. Q., Wang, G., Lin, C. X., Qiao, H., Wang, N., Yao, T., Barclay, J. L., Whitehead, J. P.,Luo, X.*, and Yan, J. Q.* (2016) Characterization of cold-induced remodelling reveals depot-specific differences across and within brown and white adipose tissues in mice.Acta Physiol (Oxf)217, 311-324
9. Luo, X., Hutley, L. J., Webster, J. A., Kim, Y. H., Liu, D. F., Newell, F. S., Widberg, C. H., Bachmann, A., Turner, N., Schmitz-Peiffer, C., Prins, J. B., Yang, G. S., and Whitehead, J. P. (2012) Identification of BMP and Activin Membrane-Bound Inhibitor (BAMBI) as a Potent Negative Regulator of Adipogenesis and Modulator of Autocrine/Paracrine Adipogenic Factors.Diabetes61, 124-136
10. Luo, X., Li, H. X., Liu, R. X., Wu, Z. S., Yang, Y. J., and Yang, G. S. (2009) beta-catenin protein utilized by Tumour necrosis factor-alpha in porcine preadipocytes to suppress differentiation.Bmb Rep42, 338-343
11. Jia, R., Huang, J., Wei, X., Hu, B., andLuo, X.*(2019) [Timeliness of beta3 adrenergic receptor agonist-induced browning of white adipose tissues in mice].Zhong nan da xue xue bao. Yi xue ban =Journal of Central South University. Medical sciences44, 1099-1106
12. Huang, J., Jia, R., Wei, X., andLuo, X.*(2019) [Time-sequential expression of lnc AK079912 during adipose tissue development and browning in mice].Nan fang yi ke da xue xue bao =Journal of Southern Medical University39, 1494-1499
13. 罗肖,孙波,吕海侠. (2018) 基础医学专业学业-学术双导师制度实施效果分析.基础医学教育20, 5
14. Luo, X., Jia, R., Wei, S. Y., Yao, T., Wang, Y. X., Lu, C., Jonathan, P. W. J. P., and Yan, J. Q. (2015) Differential expression of bone morphogenetic protein and activin membrane-bound inhibitor in mouse adipose tissues and primary preadipocytes.Nan fang yi ke da xue xue bao =Journal of Southern Medical University35, 1-5
15. Luo, X., Jia, R., Li, K., Zhu, X., Zhao, D., Whitehead Jonathan, P., and Yan, J. (2015) Fibroblast growth factor-1 inhibits Wnt/beta-catenin pathway during adipogenesis.Journal of Central South University. Medical Sciences40, 843-850
16. 罗肖,魏双羽,贾如,姚婷,张燕茹,师小博,闫剑群. (2014) BAMBI基因敲除小鼠的繁育、基因型鉴定.实验动物与比较医学34, 381-385
17. Luo, X., Li, H., and Yang, G. (2008) Sequential Expression of Wnt/beta-catenin Signal Pathway Related Genes and Adipocyte Transcription Factors During Porcine Adipose Tissue Development.Chinese Journal of Biotechnology24, 746-753
18. 罗肖, 李惠霞, 杨公社. (2007) Wnt信号通路与前体脂肪细胞.中国生物化学与分子生物学报23, 791-796
19. Wang, N., Lv, B., Guan, L., Qiao, H., Sun, B.,Luo, X.,Jia, R., Chen, K., and Yan, J. (2020) Maternal low protein exposure alters glucose tolerance and intestinal nutrient-responsive receptors and transporters expression of rat offspring.Life Sci243, 117216
20. Song, L., Yan, J., Wang, N., Wei, X.,Luo, X., Meng, K., and Sun, B. (2020) Prenatal exercise reverses high-fat-diet-induced placental alterations and alters male fetal hypothalamus during late gestation in ratsdagger.Biol Reprod102, 705-716
21. Gu, X.,Luo, X., Wang, Y., He, Z., Li, X., Wu, K., Zhang, Y., Yang, Y., Ji, J., and Luo, X. (2019) Ascorbic acid attenuates cell stress by activating the fibroblast growth factor 21/fibroblast growth factor receptor 2/adiponectin pathway in HepG2 cells.Mol Med Rep20, 2450-2458
22. Hu, B., Qiao, H., Cao, T., Sun, B.,Luo, X., Jia, R., Fan, Y., Wang, N., Lu, Y., and Yan, J. (2018) Angiotensin II facilitates GABAergic neurotransmission at postsynaptic sites in rat amygdala neurons.Neuropharmacology133, 334-344
23. Guan, L., Qiao, H., Wang, N.,Luo, X., and Yan, J. (2018) The purinergic mechanism of the central nucleus of amygdala is involved in the modulation of salt intake in sodium-depleted rats.Brain Res Bull143, 132-137
24. Qiao, H., Hu, B., Zhou, H., Yan, J., Jia, R., Lu, B., Sun, B.,Luo, X., Fan, Y., and Wang, N. (2016) Aldosterone induces rapid sodium intake by a nongenomic mechanism in the nucleus tractus solitarius.Scientific reports6, 38631
25. Kim, Y. H., Barclay, J. L., He, J.,Luo, X., O'Neill, H. M., Keshvari, S., Webster, J. A., Ng, C., Hutley, L. J., Prins, J. B., and Whitehead, J. P. (2016) Identification of carboxypeptidase X (CPX)-1 as a positive regulator of adipogenesis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology30, 2528-2540
26. Wei, X. J., Sun, B., Chen, K., Lv, B.,Luo, X., and Yan, J. Q. (2015) Ghrelin Signaling In the Ventral Tegmental Area Mediates Both Reward-Based Feeding And Fasting-Induced Hyperphagia on High-Fat Diet.Neuroscience300, 53-62
27. Jia, R., Lu, Y., Yang, C. W.,Luo, X., and Han, Y. (2014) Effect of generation 4.0 polyamidoamine dendrimer on the mineralization of demineralized dentinal tubules in vitro.Arch Oral Biol59, 1085-1093
28. Yang, Y., Yang, J., Liu, R., Li, H.,Luo, X., and Yang, G. (2011) Accumulation of beta-catenin by lithium chloride in porcine myoblast cultures accelerates cell differentiation.Molecular biology reports38, 2043-2049
29. Hutley, L. J., Newell, F. S., Kim, Y. H.,Luo, X., Widberg, C. H., Shurety, W., Prins, J. B., and Whitehead, J. P. (2011) A putative role for endogenous FGF-2 in FGF-1 mediated differentiation of human preadipocytes.Mol Cell Endocrinol339, 165-171
30. Li, H. X.,Luo, X., Liu, R. X., Yang, Y. J., and Yang, G. S. (2008) Roles of Wnt/beta-catenin signaling in adipogenic differentiation potential of adipose-derived mesenchymal stem cells.Mol Cell Endocrinol291, 116-124
31. Chen, K., Yan, J. Q., Sun, B.,Luo, X., Wang, N., and Lyu, B. (2019) [Nutritional status alters the mRNA expressions of galanin and its receptors in taste buds of rats].Sheng Li Xue Bao71, 294-300
32. 孟凯,孙波,罗肖,霍福权. (2017) TBL 与虚拟实验系统结合在机能学实验中的探索.基础医学教育19, 3
33. 闫剑群,王楠,吕波,孙波,罗肖,孟凯. (2016) 围产期母体营养状态对子代下丘脑食欲调控网络胚胎编程的研究进展.西安交通大学学报(医学版)37, 8
34. 孙波,宋琳,罗肖,孟凯,闫剑群. (2016) 高脂饮食影响雌性大鼠对糖精溶液的喜好并改变多巴胺及阿片相关基因的表达.西安交通大学学报(医学版)37, 6
35. 白亮,王蓉,罗肖,赵四海,刘恩岐. (2015) 激活PPARα缓解PPARγ诱导的小鼠脂肪肝.中国实验动物学报23, 5
36. Lin, C. X., Zhang, S. Y., Chen, K.,Luo, X., Sun, B., Kang, Y. M., and Yan, J. Q. (2015) Leptin receptor of the hind brain nuclei is involved in the conditioned taste preference of rats.Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi =Chinese journal of applied physiology31, 549-555
37. 李惠侠,罗肖,刘荣鑫,杨映娟,杨公社. (2010) 激活Wnt/β-catenin信号通路抑制猪AMSCs向脂肪细胞分化.畜牧兽医学报41, 1523-1528
38. 李惠侠,罗肖,刘荣鑫,杨公社. (2009) 用成熟脂肪建立一种新的猪前体脂肪细胞培养模型.中国生物化学与分子生物学报25, 270-275
39. 李惠侠,屈长青,罗肖,杨公社. (2007) 脂肪组织源性干细胞研究进展.生理科学进展38, 129-132

主持项目:
项目名称
起止日期
项目来源(编号)
金额(万元)
主持人

新的人LncRNA:lnc-GAT1调控妊娠期糖尿病患者脂肪组织慢性炎症反应的分子机制
2019.1-2022.12
国家自然科学基金项目(**)
57
罗肖

利用基因敲除鼠模型研究BAMBI 基因在脂肪细胞形成中的作用及分子机制
2013.1-2015.12
国家自然科学基金项目(**)
23
罗肖

BAMBI在脂肪细胞形成中的生理学作用研究
2012.9-2014.9
西安交通大学基本科研业务费 国际科技合作项目(2012jdhz61)
4
罗肖

BAMBI缺失对小鼠棕色样脂肪细胞形成的影响及分子机制
2015.7-2017.7
中国博士后科学基金一等(2015M580856)
8
罗肖

妊娠期糖尿病患者大网膜脂肪慢性炎症反应中的关键LncRNA功能及其调控机制研究
2016.1-2018.1
西安交通大学基本科研业务费 综合交叉项目
(xjj**)
10
罗肖

BAMBI在线束beige细胞定向与分化过程中的作用研究
2016.1-2017.12
陕西省自然科学基础研究计划-青年人才项目(2016JQ8021)
3
罗肖

利用敲除鼠模型研究BAMBI基因在冷刺激诱导皮下脂肪血管生成中的作用及分子机制
2016.7-2017.7
陕西省博士后基金二等(2016BSHEDZZ86)
2
罗肖

GDM患者OAT炎症反应中关键LncRNA功能研究
2017.7-2019.7
中国博士后科学基金特别资助(2017T100759)
15
罗肖




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