Bong-Kiun Kaang (? ? ?; 姜 奉 均)





EDUCATION


1984. B.S. Seoul National University
1986. M.S. Seoul National University
1992. Ph.D. Columbia University
(Supervisor: Eric R. Kandel, M.D., Nobel Laureate, 2000)





PROFESSIONAL EXPERIENCE


1992-1994 Postdoctoral Research Fellow (Eric R. Kandel’s Lab), Center for Neurobiology and Behavior, Columbia University
1994-1998 Assistant Professor, Institute for Molecular Biology and Genetics, Seoul National University
1998-2000 Associate Professor, Institute for Molecular Biology and Genetics, Seoul National University
2000-2004 Associate Professor, Department of Biological Sciences, College of Natural Sciences, Seoul National University
2004-Present Professor, Department of Biological Sciences, College of Natural Sciences, Seoul National University
2009-Present Professor, Department of Brain and Cognitive Sciences, College of Natural Sciences, Seoul National University





HONORS AND AWARDS


1989. Government Fellowship Award for Studying Abroad
2007. The Best Research Award, College of Natural Sciences, Seoul National University, Korea
2007. Excellent Research Scientist, Korea Ministry of Science and Technology, Korea
2008. Life Science Award, Korean Society for Molecular and Cellular Biology, Korea
2010. Fellow of the Korean Academy of Science and Technology, Korea
2011. Excellent Research Award, Seoul National University, Korea
2012. Donghun Award, Korean Society for Biochemistry and Molecular Biology, Korea
2012. National Honor Scientist Program, National Research Foundation, Korea
2012. Kyung Ahm Prize, Kyung Ahm Foundation, Korea
2013. AND Investigator Award, Association for the Studies of Neurons and Diseases





TRAINEES


Graduate Students


Prior:
1994-2002 Hyong-Kyu Kim, Ph.D. student, Department of Biological Sciences, Seoul National University (M.S. 1996, Ph.D. 2002)
Present position: Associate Professor, Department of Medicine and Microbiology, College of Medicine, Signaling Disorder Research Center, Chungbuk National University
1995-2002 Deok-Jin Jang, Ph.D. student, Department of Biological Sciences, Seoul National University (M.S. 1997, Ph.D. 2002)
Present position: Assistant Professor, Department of Applied Biology, College of Ecology and Environment, Kyungpook National University
1996-2004 Chae-Seok Lim, Ph.D. student, Department of Biological Sciences, Seoul National University (M.S. 1998, Ph.D. 2004)
Present position: Postdoctoral Fellow (Dr. J. Julius Zhu’s Lab), Department of Pharmacology, School of Medicine, University of Virginia
1997-2004 Jin-Hee Han, Ph.D. student, Department of Biological Sciences, Seoul National University (M.S. 1999, Ph.D. 2004)
Present position: Assistant Professor, Department of Biological Sciences, Korea Advanced Institute of Science and Technology
1998-2006 Yong-Seok Lee, Ph.D. student, Department of Biological Sciences, Seoul National University (M.S. 2000, Ph.D. 2006)
Present position: Assistant Professor, Department of Life Science, College of Natural Sciences, Chung-Ang University
1999-2005 Jin-A Lee, Ph.D. student, Department of Biological Sciences, Seoul National University (M.S. 2001, Ph.D. 2005)
Present position: Assistant Professor, Department of Biotechnology, College of Life Science and Nano Technology, Hannam University
2000-2007 Hyungju Park, Ph.D. student, Department of Biological Sciences, Seoul National University (Ph.D. 2007)
Present position: Postdoctoral Fellow (Dr. Mu-ming Poo’s Lab), Division of Neurobiology, Department of Molecular and Cell Biology, Helen Wills Neuroscience Institute, University of California
2002-2007 Hyoung Kim, Ph.D. student, Department of Biological Sciences, Seoul National University (Ph.D. 2007)
Present position: Postdoctoral Fellow (Dr. Okihide Hikosaka’s Lab), Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health
2002-2007 Seung-Hee Lee, Ph.D. student, Department of Biological Sciences, Seoul National University (Ph.D. 2007)
Present position: Assistant Professor, Department of Biological Sciences, Korea Advanced Institute of Science and Technology
2003-2008 Sue-Hyun Lee, Ph.D. student, Department of Biological Sciences, Seoul National University (Ph.D. 2008)
Present position: Postdoctoral Fellow (Dr. Chris I. Baker’s Lab), Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health
2004-2007 Ye-Hwang Cheong, Ph.D. student, Department of Biological Sciences, Seoul National University (Ph.D. 2014)
Present position: Central Research Center of Dong-A pharmaceutical company
2005-2011 Hyoung-Gon Ko, Ph.D. student, Department of Biological Sciences, Seoul National University (Ph.D. 2011)
Present position: Research Professor (Dr. Bong-Kiun Kaang’s Lab), Department of Biological Sciences, College of Natural Sciences, Seoul National University
2005-2012 Jae-Ik Kim, Ph.D. student, Department of Biological Sciences, Seoul National University (Ph.D. 2012)
Present position: Postdoctoral Fellow (Dr. Jun B. Ding’s Lab), Department of Neurology and Neurological Sciences, SINTN, Stanford University School of Medicine
2005-2012 Hye-Ryeon Lee, Ph.D. student, Department of Biological Sciences, Seoul National University (Ph.D. 2012)
Present position: Postdoctoral Fellow (Dr. Theo Palmer’s Lab), Institute for Stem Cell Biology and Regenerative Medicine, Stanford University
2007-2013 Sun-Lim Choi, Ph.D. student, Department of Biological Sciences, Seoul National University (Ph.D. 2013)
Present position: Postdoctoral Fellow (Dr. Graham Collingridge’s Lab), University of Bristol, UK
2006-2014 Jun-Hyeok Choi, Ph.D. student, Department of Biological Sciences, Seoul National University (Ph.D. 2014)
Present position: Postdoctoral Fellow (Dr. Bong-Kiun Kaang’s Lab), Department of Biological Sciences, College of Natural Sciences, Seoul National University
2006-2014 Nam-Kyung Yu, Ph.D. student, Department of Biological Sciences, Seoul National University (Ph.D. 2014)
Present position: Postdoctoral Fellow (Dr. Bong-Kiun Kaang’s Lab), Department of Biological Sciences, College of Natural Sciences, Seoul National University

1994-1996 Do-Young Jung, M.S. student, Department of Biological Sciences, Seoul National University (M.S. 1996)
Present position: Medical Doctor, Miz Medi Hospital
1995-1997 Suk-Won Lim, M.S. student, Department of Biological Sciences, Seoul National University (M.S. 1997)
Present position: Research Scientist, Integrity Bio, Inc. in California, USA
1997-1999 Jong-Chul Lee, M.S. student, Department of Biological Sciences, Seoul National University (M.S. 1999)
1998-2000 Kyung-Hee Kim, M.S. student, Department of Biological Sciences, Seoul National University (M.S. 2000)
1999-2001 Min-Jeong Kim, M.S. student, Department of Biological Sciences, Seoul National University (M.S. 2001)
Present position: Teacher in High school
1997-2002 Su-Dong Kim, M.S. student, Department of Biological Sciences, Seoul National University (M.S. 2002)
Present position: Deputy Manager, Korea Foundation for the Advancement of Science and Creativity
2000-2002 Jeongyeon Kim, M.S. student, Department of Biological Sciences, Seoul National University (M.S. 2002)
Present position: Postdoctoral Fellow (Dr. Justin Lee’s Lab), Center for Neural Science and WCI Center for Functional Connectomics, Korea Institute of Science and Technology (KIST)
2001-2003 Hye-Young Shin, M.S. student, Department of Biological Sciences, Seoul National University (M.S. 2003)
Present position: Medical Doctor
2001-2003 Minjung Huh, M.S. student, Department of Biological Sciences, Seoul National University (M.S. 2003)
Present position: Medical Doctor
2002-2005 Se-Jeong Yim, M.S. student, Department of Biological Sciences, Seoul National University (M.S. 2005)
2003-2006 Dong-Hyuk Jang, M.S. student, Department of Biological Sciences, Seoul National University (M.S. 2006)
Present position: Researcher, Amore Pacific R&D Center
2008-2010 Nuribalhae Lee, M.S. student, Department of Brain and Cognitive Sciences, Seoul National University (M.S. 2010)
Present position: Ph.D. student, Department of Psychiatry, Seoul National University College of Medicine
2008-2010 Jung-Eun Kim, M.S. student, Department of Biological Sciences, Seoul National University (M.S. 2010)
Present position: Researcher, LG Life Sciences
2009-2011 Yeon-Su Chae, M.S. student, Department of Biological Sciences, Seoul National University (M.S. 2011)
Present position: Ph.D. student, School of Dentistry, Pusan National University
2009-2011 Soo-Won Park, M.S. student, Department of Biological Sciences, Seoul National University (M.S. 2011)
Present position: Ph.D. student, Department of Education, Seoul National University
2010-2012 Bolam Lee, M.S. student, Department of Brain and Cognitive Sciences, Seoul National University (M.S. 2012)
Present position: Celtrion Inc.
2010-2012 Jinhee Baek, M.S. student, Department of Biological Sciences, Seoul National University (M.S. 2012)
Present position: Researcher, Center for Cognition and Sociality, Institute for Basic Science
2011-2013 Jeehaeh Do, M.S. student, Department of Brain and Cognitive Sciences, Seoul National University (M.S. 2013)
2011-2013 Seo Hee Ahn, M.S. student, Department of Brain and Cognitive Sciences, Seoul National University (M.S. 2013)
2011-2013 Gichul Baek, M.S. student, Department of Biological Sciences, Seoul National University (M.S. 2013)
2011-2013 Pojung Park, M.S. student, Department of Brain and Cognitive Sciences, Seoul National University (M.S. 2013)
2011-2013 Yeseul Lee, M.S. student, Department of Brain and Cognitive Sciences, Seoul National University (M.S. 2013)
2012-2014 Eun-Hye Jang, M.S. student, Department of Brain and Cognitive Sciences, Seoul National University (M.S. 2014)
2012-2014 Ji-Hye Park, M.S. student, Department of Brain and Cognitive Sciences, Seoul National University (M.S. 2014)
2012-2014 Ju-Yeon Yu, M.S. student, Department of Biological Sciences, Seoul National University (M.S. 2014)

Current:
2009-Present Chuljung Gwak, Ph.D. student, Department of Biological Sciences, Seoul National University (M.S. 2011)
2010-Present Su-Eon Sim, Ph.D. student, Department of Brain and Cognitive Sciences, Seoul National University
2010-Present Jae-Hoon Shim, Ph.D. student, Department of Brain and Cognitive Sciences, Seoul National University
2010-Present Sukjae Kang, Ph.D. student, Department of Brain and Cognitive Sciences, Seoul National University
2012-Present Tae-Hyun Kim, Ph.D. student, Department of Biological Sciences, Seoul National University
2012-Present Somi Kim, Ph.D. student, Department of Biological Sciences, Seoul National University
2013-Present Hyo-Pil Kim, Ph.D. student, Department of Biological Sciences, Seoul National University






PUBLICATIONS


Articles


1. Kim SM, Yu NK, Kaang BK. CTCF as a Multi-functional Protein in Genome Regulation and Gene Expression. 2015. Exp Mol Med (under minor revision)
2. Jun YW, Kim S, Kim KH, Lee JA, Lim CS, Chang I, Suh BC, Kaang BK, Jang DJ. Analysis of phosphoinositide-binding properties and subcellular localization of GFP-fusion proteins. 2015. Lipids.
2015 Feb 17. [Epub ahead of print]
3. Kim TH, Lim CS, Kaang BK, Cell type-specific gene expression profiling in brain tissue: Comparison among TRAP, LCM and RNA-seq. 2015. BMB Rep. 2015 Jan 21. pii: 2994. [Epub ahead of print]
4. Kwak C, Lim CS, Kaang BK. Development of a touch-screen-based paradigm for assessing working memory in the mouse. 2015. Exp Neurobiol. 24(1) pISSN 1226-2560 ? eISSN 2093-8144
5. Koga K, Descalzi G, Chen T, Ko HG, Lu J, Li S, Son J, Kim TH, Kwag C, Huganir RL, Zhao MG, Kaang BK, Collingridge GL, Zhuo M. Co-existence of two forms of LTP in ACC provides a synaptic mechanism for the interactions between anxiety and chronic pain. 2014. Neuron. Dec 30. pii: S0896-6273(14)01102-7. doi: 10.1016/j.neuron.2014.12.021. [Epub ahead of print]
6. Lee YS, Ehninger D, Zhou M, Oh JY, Kang M, Kwak C, Ryu H, Butz D, Araki T, Cai Y, Balaji J, Sano Y, Nam CI, Amin A, Kim HK, Kaang BK, Burger C, Neel BG, Silva AJ. Mechanism and treatment for the learning and memory deficits associated with mouse models of Noonan syndrome. 2014. Nat Neurosci. 2014. 17(12):1736-1743. Nov 10. doi: 10.1038/nn.3863. [Epub ahead of print]
7. Choi JH, Park P, Baek GC, Sim SE, Lee Y, Ahn SH, Lee HR, Lim CS, Lee YS, Collingridge GL Kaang BK. Effects of PI3Kγ Overexpression in the Hippocampus on Synaptic Plasticity and Spatial Learning. 2014. Mol Brain. 7:78. DOI: 10.1186/s13041-014-0078-6
8. Kim KH, Jun YW, Park Y, Lee JA, Suh BC, Lim CS, Lee YS, Kaang BK, Jang DJ. Intracellular membrane association of Aplysia cAMP phosphodiesterase long- and short-form via different targeting mechanisms. J Biol Chem. 2014. 289:25797-25811 Jul 30. pii: jbc.M114.572222. [Epub ahead of print]
9. Sim SE, Bakes J, Kaang BK. Neuronal Activity-Dependent Regulation of MicroRNAs. Mol Cells. 2014. 37(7):511-517. doi: 10.14348/molcells.2014.0132. [Epub ahead of print]
10. Choi JH, Yu NK, Baek GC, Seo D, Nam HJ, Baek SH, CS Lim, Lee YS, Kaang BK. Optimization of AAV expression cassettes to improve packaging capacity and transgene expression in neurons. Mol Brain 2014. 7(1):17.
11. Leinders M, Koehrn FJ, Bartok B, Boyle DL, Shubayev V, Kalcheva I, Yu NK, Park J, Kaang BK, Hefferan MP, Firestein GS, Sorkin LS. Differential Distribution of PI3K Isoforms in Spinal Cord and Dorsal Root Ganglia: Potential Roles in Acute Inflammatory Pain. Pain. 2014 Jun;155(6):1150-1160.
12. Yoo J, Bakes J, Bradley C, Collingridge GL, Kaang BK. Shank mutant mice as an animal model of autism. Philos Trans R Soc Lond B Biol Sci. 2013. Philos Trans R Soc Lond B Biol Sci. 2013 Dec 2;369(1633):**. doi: 10.1098/rstb.2013.0143. Print 2014 Jan 5.
13. Park P, Volianskis A, Sanderson TM, Bortolotto ZA, Jane DE, Zhuo M, Kaang BK, Collingridge GL. NMDA receptor-dependent long-term potentiation comprises a family of temporally overlapping forms of synaptic plasticity that are induced by different patterns of stimulation. Philos Trans R Soc Lond B Biol Sci. 2013 Dec 2;369(1633):**. doi: 10.1098/rstb.2013.0131. Print 2014 Jan 5.
14. Kang SJ, Liu MG, Shi TY, Zhao MG, Kaang BK, Min Zhuo. N-type voltage gated calcium channels mediate excitatory synaptic transmission in the anterior cingulate cortex of adult mice. Mol Pain. 2013 Nov 14;9(1):58.

Book Chapters
1. Kaang BK, Chapter 1. Genes and Neurons, in Molecular Pain (ed. by M. Zhuo), 2007. p.3-15. Higher Education Press, Beijing, P. R. China.
2. Kaang BK and Choi JH, Chapter 10: Synaptic protein degradation in memory reorganization, M.R. Kreutz and C. Sala (eds.), Synaptic Plasticity, Advances in Experimental Medicine and Biology, Springer-Verlag/Wien 2012