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西北农林科技大学化学与药学院导师教师师资介绍简介-裴志超

本站小编 Free考研考试/2021-07-07

裴志超,博士,教授, 博士生导师,西北农林科技大学“后稷****”****,陕西省“人才计划”入选者,享受国务院政府特殊津贴专家。
2006年毕业于瑞典皇家工学院化学系有机化学专业,获博士学位。2007年2月至2010年6月任瑞典Attana生物传感器公司高级研究员和生物芯片研发部经理,从事生物芯片(糖体芯片、蛋白及细胞芯片)的研发和生物传感器的应用研究。 2010年7月 至今任西北农林科技大学“后稷****”****,西北农林科技大学化学与药学院(原理学院)教授,研究方向为糖化学生物学。
学术兼职:中国生物物理学会糖生物学分会委员会理事,中国生物工程学会糖生物工程专业委员会委员,中国化学会糖化学专业委员会委员,中国生物化学与分子生物学会复合糖专业委员会委员。
教育背景
2002 - 2006 瑞典皇家工学院化学化工学院化学系有机化学专业,博士
1984 - 1988 郑州大学化学系化学专业,理学学士
主要工作经历
2010.07– 西北农林科技大学“后稷****”****
2007–2010 瑞典Attana生物传感器公司高级研究员、生物芯片研发部经理
1998–2000 浙江大学膜分离工程公司工程师
1996–1997 郑州市化工三厂厂长
1990–1995 郑州市化工三厂新产品车间主任
1988–1990 郑州市第二化肥厂碳化工段工段长
研究方向
基于(糖)纳米材料构建药物递送体系运用于肿瘤靶向治疗
功能糖化合物的修饰与合成
基于QCM生物传感器技术的糖体等生物芯片的研究及应用
主持的代表性科研项目
1. 国家自然科学基金面上项目 “基于双亲性乳糖-药物的偶联物自组装构建纳米药物/siRNA双负载体系”(NSFC **),2019-2022,(78万)
2. 国家自然科学基金面上项目“糖靶向智能阳离子囊泡的制备及其在抗癌药物/siRNA共运输的应用研究”(NSFC **),2016-2019, (78万)
3. 国家自然科学基金面上项目“三维功能糖芯片制备的高效及通用策略”(NSFC**),2013-2016,(80万)
4. 陕西省农业科技创新项目“烟草抗逆寡糖疫苗及其分子作用机制的研究”(2012NKC01-12),2013-2015 (8万)
5. 陕西省“***”科研基金,“功能糖芯片制备的高效固定化策略”, 2013-2016 (50万)
6. 西北农林科技大学“后稷****”科研启动基金,2010-2013 (300万)
7. 西北农林科技大学学科建设项目“糖纳米化学生物医药交叉创新研究项目培育” (100万)
近期发表代表性论文
1) Weiwei Feng, Yinghua Lv, Zelong Chen, Feng Wang, Yi Wang, Yuxin Pei,* Wenjuan Jin, Chaojie Shi, Yang Wang, Yun Qu, Wei Ji, Liang Pu, Xue-Wei Liu,* Zhichao Pei*. A carrier-free multifunctional nano photosensitizer based on self-assembly of lactose-conjugated BODIPY for enhanced anti-tumor efficacy of dual phototherapy. Chem. Eng. J. 2021, 417 , 129178. (IF 10.652)
2) Xueming Li, QuanQuan Song, Yuxin Pei, Hai Dong,* Teodor Aastrup, Zhichao Pei*. Direct attachment of suspension cells to PDA surface and its application in suspension-cell QCM biosensor. Sens Actuator B Chem . 2021, 326 , 128823. (IF 7.1)
3) Chenxi Hou,? Ning Ma,? Ziyan Shen, Guanyu Chi, Shuang Chao, Yuxin Pei, Lan Chen, Yuchao Lu,* Zhichao Pei*. A GSH-responsive nanoprodrug system based on self-assembly of lactose modified camptothecin for targeted drug delivery and combination chemotherapy. Int. J. Nanomed. 2020, 15 , 10417-10424. (IF 5.115)
4) Dongdong Liu, Siming Jiao, Jinhua Wei, Xuebing Zhang, Yuxin Pei, Zhichao Pei,* Jianjun Li,* Yuguang Du.* Investigation of absorption, metabolism and toxicity of ginsenosides compound K based on human organ chips. Int. J. Pharm. 2020, 587 , 119669. (IF 4.854)
5) Shuang Chao, Xiukai Lv, Ning Ma, Ziyan Shen, Feiyu Zhang, Yuxin Pei, Zhichao Pei*. A supramolecular nanoprodrug based on a boronate ester linked curcumin complexing with water-soluble pillar[5]arene for synergistic chemotherapies. Chem. Commun ., 2020, 56 , 8861-8864. (IF 5.996)
6) Yijie Hua, Lan Chen, Chenxi Hou, Shengbo Liu, Zhichao Pei,* Yuchao Lu.* Supramolecular vesicles based on amphiphilic pillar[n]arenes for smart nano-drug delivery. Int. J. Nanomed. 2020, 15 , 5875-5899. (IF 5.115)
7) Kui Yang,?* Zhihua Zhang,? Jie Du, Wei Li,* Zhichao Pei*. Host–guest interaction based supramolecular photodynamic therapy systems: a promising candidate in the battle against cancer. Chem. Commun ., 2020, 56 , 5865-5876. (IF 5.996)
8) Kui Yang, Shuang Chao, Feiyu Zhang, Yuxin Pei, Zhichao Pei*. Recent advances in the development of rotaxanes and pseudorotaxanes based on pillar[n]arenes: from construction to application. Chem. Commun. , 2019, 55 , 13198-13210. (IF 5.996)
9) Yuchao Lu,?* Chenxi Hou,? Jingli Ren, Kui Yang, Yincheng Chang, Yuxin Pei, Hai Dong,* Zhichao Pei*. A multifunctional supramolecular vesicle based on complex of cystamine dihydrochloride capped pillar[5]arene and galactose derivative for targeted drug delivery. Int. J. Nanomed. 2019, 14 , 3525-3532. (IF 5.115)
10) Kui Yang, Ke Yang, Shuang Chao, Jia Wen, Yuxin Pei, Zhichao Pei*. A supramolecular hybrid material constructed from pillar[6]arene-based host–guest complexation and ZIF-8 for targeted drug delivery. Chem. Commun. , 2018, 54 , 9817-9820. (IF 5.996)
11) Kui Yang, Jia Wen, Shuang Chao,Jing Liu,Ke Yang, Yuxin Pei, Zhichao Pei*. A supramolecular photosensitizer system based on the host–guest complexation between water-soluble pillar[6]arene and methylene blue for durable photodynamic therapy. Chem. Commun. , 2018, 54 , 5911-5914. (IF 5.996)
12) Yuchao Lu, Siyu Song, Chenxi Hou, Shuang Pang, Xueming Li, Xiaowen Wu, Chen Shao, Yuxin Pei, Zhichao Pei*. Facile fabrication of branched-chain carbohydrate chips for studying carbohydrate-protein interactions by QCM biosensor. Chin. Chem. Lett. 2018, 29 , 65-68. (IF 4.632)
13) Yincheng Chang,? Yinghua Lv,? Peng Wei, Pengfei Zhang, Liang Pu, Xiaoxu Chen, Kui Yang, Xueliang Li, Yuchao Lu, Chenxi Hou, Yuxin Pei,* Wenxian Zeng,* and Zhichao Pei*. Multifunctional glyco nanofibers: siRNA induced supermolecular assembly for codelivery in vivo. Adv Funct Mater. 2017, 27 , **. (IF 16.836)
14) Xiaowen Wu, Ying Zhang, Yuchao Lu, Shuang Pang, Kui Yang, Zhimin Tian, Yuxin Pei,* Yongquan Qu, Feng Wang and Zhichao Pei*. Synergistic and Targeted Drug Delivery Based on Nano-CeO2 Capped with Galactose Functionalized Pillar[5] arene via Host–Guest Interactions. J. Mater. Chem. B , 2017, 5, 3483-3487 (IF 5.344)
15) Kui Yang, Yincheng Chang, Jia Wen, Yuchao Lu, Yuxin Pei,* Shoupeng Cao, Feng Wang, and Zhichao Pei.* Supramolecular vesicles based on complex of Trp-modified pillar[5]arene and galactose derivative for synergistic and targeted drug delivery. Chem. Mater. 2016, 28 , 1990-1993. (IF 9.567)
16) Yincheng Chang, Chenxi Hou, Jingli Ren, Xiaoting Xin, Yuxin Pei,* Yuchao Lu, Shoupeng Cao and Zhichao Pei*. Multifunctional supramolecular vesicles based on the complex of ferrocenecarboxylic acid capped pillar[5]arene and a galactose derivative for targeted drug delivery. Chem. Commun ., 2016, 52 , 9578-9581. (IF 5.996)
17) Kui Yang, Yuxin Pei,* Jia Wen and Zhichao Pei.* Recent advances in pillar[n]arenes: synthesis and application based on host-guest interactions. Chem. Commun . 2016, 52 , 9316-9326. (IF 5.996)
18) Xueming Li, Siyu Song, Yuxin Pei, Hai Dong, Teodor Aastrup, Zhichao Pei.* Oriented and reversible immobilization of His-tagged proteins on two- and three-dimensional surfaces for study of protein-protein interactions by a QCM biosensor. Sens Actuator B Chem . 2016, 224 , 814-822. (IF: 7.100)
19) Yong Hou, Shoupeng Cao, Lin Wang, Yuxin Pei,* Guoyun Zhang, Siwen Zhang and Zhichao Pei.* Morphology-controlled dual clickable nanoparticles via ultrasonic-assisted click polymerization. Polym. Chem. 2015 , 6, 223–227. (IF 5.342)
20) Yincheng Chang,? Kui Yang,? Peng Wei, Sisi Huang, Yuxin Pei,* Wei Zhao and Zhichao Pei*. Cationic vesicles based on amphiphilic pillar[5]arene capped with ferrocenium: A redox-responsive system for drug/siRNA co-delivery. Angew. Chem. Int. Ed . 2014. 53 , 13126-13130. (IF 11.709)
21) Yuchao Lu, Peng Wei, Yuxin Pei,* Hengfu Xu, Xiaoting Xin, and Zhichao Pei*. An eco-friendly approach to regioselective acetylation of carbohydrates and diols catalyzed by tetramethyl-ammonium hydroxide in water. Green Chem . 2014, 16 , 4510-4514. (IF 9.48)
22) Yong Hou, Shoupeng Cao, Xueming Li, Beibei Wang, Yuxin Pei,* Lin Wang, and Zhichao Pei.* One-step synthesis of dual clickable nanospheres via ultrasonic-assisted click polymerization for biological applications. ACS Appl. Mater. Interfaces. 2014 , 6, 16909?16917. (IF 8.758)
23) Hengfu Xu, Yuchao Lu, Yixuan Zhou, Bo Ren, Yuxin Pei, Hai Dong*, Zhichao Pei*. Regioselective benzylation of diols and polyols by catalytic amount of organotin. Adv. Synth. Catal. 2014, 356 , 1735–1740 (IF 5.851)
24) Xueming Li, Yuxin Pei*, Ruina Zhang, Qi Shuai, Feng Wang, Teodor Aastrup, Zhichao Pei*. A suspension-cell biosensor for real-time determination of binding kinetics of protein–carbohydrate interactions on cancer cell surfaces. Chem. Commun . 2013, 49 , 9908-9910. (IF 5.996)
25) Feng Wang, Haijun Yang, Hua Fu*, Zhichao Pei*. Efficient copper-catalyzed Michael addition of acrylic derivatives with primary alcohols in the presence of base. Chem. Commun . 2013, 49 , 517-519. (IF 5.996)
26) Zhichao Pei*, Julien Saint-Guirons*, Camilla K?ck, Bj?rn Ingemarsson, Teodor Aastrup. Real-time analysis of the carbohydrates on cell surfaces using a QCM biosensor: a lectin-based approach. Biosens. Bioelectron. 2012, 35 , 200-205. (IF 10.257)
联系方式
地址:西北农林科技大学北校区理科大楼,陕西杨凌西农路 22号(712100)
电话:029-8709 2769,传真:029-8708 2769
邮箱: peizc@nwafu.edu.cn



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