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基本信息 The basic information
姓名: 李爱朋

学院: 生命学院


学历: 博士研究生毕业

学位: 工学博士


职称: 讲师（高校）

职务:


学科: 生物学,化学工程与技术


邮箱: lap@nwpu.edu.cn




教育经历 Education Experience
2010年6月获兰州交通大学生物工程专业学士学位
2013年6月获浙江工业大学发酵工程专业硕士学位
2016年9月获浙江大学化学工程与技术专业博士学位
Jun 2010, Bachelor degree, Bioengineering, Lanzhou Jiaotong University
Jun 2013, Master degree, Fermentation engineering, Zhejiang University of Technology
Sep 2016, PhD degree, Biochemical engineering, Zhejiang University



教育教学 Education And Teaching
本科专业选修课《合成生物学》
本科综合素养课《生命的设计》
Undergraduate Courses：
Degign of Life
Synthetic Biology



科学研究 Scientific Research
主要研究方向为生物催化、酶分子改造和蛋白质工程，研究内容包括高效生物催化剂的挖掘、酶的定向进化和理性设计、酶催化手性化合物的绿色合成和蛋白复合微纳材料等。承担科研项目如下：


1.国家自然科学基金青年基金项目(**)，执行期：2018.01-2020.12
2.中国博士后科学基金第62批面上资助(2017M623232)，执行期：2018.01-2019.12
3.深圳市科创委计划项目(基础研究-自由探索类)(JCYJ20**8207)，执行期：2018.06-2020.06
4.陕西省博士后科研资助项目,执行期：2018.06-2020.06
5.陕西省自然科学基础研究计划青年项目(2020JQ-145)，执行期：2020.01-2021.12

1. National Natural Science Foundation of China (**), 2018.01.01-2020.12.31
2. China Postdoctoral Science Foundation (2017M623232), 2018.01.01-2019.12.31
3. Science, Technology and Innovation Commission of Shenzhen Municipality (JCYJ20**8207), 2018.06-2020-06
4. Postdoctoral Science Foundation of Shaanxi Province (2018BSHQYXMZZ27), 2018.06-2020-06
5. Natural Science Basic Research Plan in Shaanxi Province of China(2020JQ-145),2020.01-2021.12



学术成果 Academic Achievements
1. Aipeng Li, Xue Li, Wei Pang, Qing, Tian, Ting Wang, Lianbing Zhang*, Fine-tuning of the substrate binding mode to enhance the catalytic efficiency of an ortho-haloacetophenone-specific carbonyl reductase, Catalysis Science & Technology, 2020, 10, 2462-2472

2. Feng Xue^#, Xiaohong Yu^#, Yueling Shang, Chao Peng, Lihui Zhang, Qing Xu*, Aipeng Li*, Heterologous overexpression of a novel halohydrin dehalogenase from Pseudomonas pohangensis and modification of its enantioselectivity by semi-rational protein engineering, International Journal of Biological Macromolecules, 2020, 146: 80-88.

3. Aipeng Li^#, Qingxiao Yuchi^#, Xue Li, Wei Pang, Bin Li, Feng Xue*, Lianbing Zhang*, Discovery of a novel ortho-haloacetophenones-specific carbonyl reductase from Bacillus aryabhattai and insight into the molecular basis for its catalytic performance, International Journal of Biological Macromolecules, 2019, 138: 781-790.

4. Aipeng Li, Qingxiao Yuchi, Lianbing Zhang*, Ferritin: a powerful platform for nanozymes, Progress in Biochemistry and Biophysics, 2018, 45(2): 193-203.


2017年前
1. Aipeng Li, Lidan Ye, Xiaohong Yang, Bei Wang, Chengcheng Yang, Jiali Gu and Hongwei Yu. Reconstruction of the catalytic pocket and enzyme-substrate interactions enhanced the catalytic efficiency of a short-chain dehydrogenase/reductase[J]. ChemCatChem, 2016, 8(20): 3229-3233.
2. Aipeng Li, Lidan Ye, Xiaohong Yang, Chengcheng Yang, Jiali Gu and Hongwei Yu. Structure-guided stereoselectivity inversion of a short-chain dehydrogenase/reductase towards halogenated acetophenones[J]. Chem Commun., 2016, 52(37): 6284-6287.

3. Aipeng Li, Lidan Ye, Hongping Wu, Xiaohong Yang and Hongwei Yu. Characterization of an excellent anti-Prelog short-chain dehydrogenase/reductase EbSDR8 from Empedobacter brevis ZJUY-1401[J]. J Mol Catal B: Enzym., 2015, 122: 179-187.
4. Aipeng Li, Lidan Ye, Fei Guo, Xiaohong Yang and Hongwei Yu. Biocatalytic anti-Prelog reduction of prochiral ketones with whole cells of a newly isolated strain Empedobacter brevis ZJUY-1401[J]. J Mol Catal B: Enzym., 2015, 117: 31-37.





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