姓名李春梅出生年月1978.02照片
性别女专业药理学
职称副教授学位博士
是否博导否是否硕导否
电子信箱lichunmei@luye.cn联系电话**

研究方向及主要研究内容
心血管药理及新药筛选：本方向主要研究急性冠脉综合症、糖尿病心肌病及慢性心衰的发病机制与药物防治。重点研究上述疾病或/和病理改变的细胞信号转导机制，寻找药物干预的新靶点，探索新的药物作用机制和新型先导化合物。
荣誉及学术兼职（限填5项）
中国毒理学会会员
承担的主要科研课题（限填5项）
序号课题名称课题来源是否课题负责人
1化合物ASAⅥ抑制缺血所致大鼠心肌细胞凋亡的信号通路山东省自然科学基金是
2烟台大学博士基金烟台大学是
3化合物SMND-309促进脑缺血大鼠脑血管新生的信号通路国家自然科学基金否
4ATF3在前列腺癌雄激素非依赖性形成中的作用研究国家自然科学基金否
5海带岩藻聚糖硫酸酯抑制缺血所致大鼠神经细胞凋亡的信号通路研究山东省自然科学基金否

重要奖项和专利情况（限填5项）
序号奖项或专利名称奖项类别或专利号
1一种知母皂苷及其制备方法ZL**3.1
2一种莱阳梨含片及其制备方法及莱阳梨口服制剂的新应用ZL**3.1

发表论文、著作情况（限填10篇）
[1] Li C(李春梅), Gao Y* , Tian J* , Xing Y, Zhu H, Shen J. Long-term oral Asperosaponin VI attenuates cardiac dysfunction and myocardial fibrosis in a rat model of chronic myocardial infarction. Food Chem Toxicol. 2012, 50(5):1432-1438.
[2] Gao Y, Dong C, Yin J , Shen J, Tian J, Li C*(李春梅, 通讯作者). Neuroprotective effect of fucoidan on H2O2-induced apoptosis in PC12 cells via activation of PI3K/Akt pathway. Cell Molecular Neurobiol. 2012,32(4):523-529.
[3] Li C(李春梅), Gao Y*, Xing Y, Zhu H, Shen J, Tian J*. Fucoidan, a sulfated polysaccharide from brown algae, against myocardial ischemia– reperfusion injury in rats via regulating the inflammation response. Food Chem Toxicol. 2011, 49(9):2090-2095.
[4] Li C(李春梅), Gao Y, Tian J*, Shen J, Xing Y, Liu Z*. Sophocarpine admini- stration preserves myocardial function from ischemia-reperfusion in rats via NF- κB inactivation. J Ethnopharmacolo. 2011,135(3):620-625.
[5] Gao Y, Li C(李春梅，共同第1作者), Shen J, Yin H, An X, Jin H*. Effect of food azo dye tartrazine on learning and memory functions in mice and rats, and the possible mechanisms involved. J Food Sci. 2011,76(6):T125-T129.,
[6] Li C(李春梅), Liu Z*, Tian J, Li G, Jiang W, Zhang G, Chen F, Lin P, Ye Z*. Protective roles of Asperosaponin Ⅵ, a triterpene saponin isolated from Dipsacus asper Wall on acute myocardial infarction in rats. Eur J Pharmacol. 2010, 627(1-3):235-241.
[7] Li C(李春梅), Tian J, Li G, Jiang W, Xing Y, Hou J, Zhu H, Xu H, Zhang G, Liu Z*, Ye Z*. Asperosaponin VI protects cardiac myocytes from hypoxia-induced apoptosis via activation of the PI3K/Akt and CREB pathways. Eur J Pharmacol. 2010,649(1-3):100-107.
[8] Yonglin Gao, Jingyu Shen, Jungang Yin, Chunmei Li*(李春梅, 通讯作者), Chengyu Fu, Susan Cho. A subchronic dietary toxicity study of rice hull fiber in rats. Food and Chemical Toxicology. 2013, 51:137–142.
[9] Gao Y, Li C(李春梅), Yin J, Shen J, Wang H, Wu Y, Jin H. Fucoidan, a sulfated polysaccharide from brown algae, improves cognitive impairment induced by infusion of Aβ peptide in rats. Environ Toxicol Pharmacol. 2012,33(2):304-311.
[10] Gao Y, Li G, Li C(李春梅),, Zhu X, Li M, Fu C, Li B. Anti-nociceptive and anti-inflammatory activity of sophocarpine. J Ethnopharmacol. 2009,125(2):324-329.