王晓通


姓 名：王晓通 性别：男 出生年月：1979.10，博士，教授，副院长
研究方向：贝类生理学与遗传育种、海洋生物资源开发利用
称号或荣誉：泰山****青年专家、山东省有突出贡献的中青年专家、
山东省青年科技奖获得者、山东省科协常委
电子邮箱：wangxiaotong999@163.com 现授课程：贝类增养殖学
简介：共发表学术论文40余篇，第一或通讯作者发表SCI论文30篇，包含4篇共同第一作者，其中1篇共同第一作者论文在Nature发表（是文章中两个主要科学问题之一-贝壳形成的负责人）；
第一发明人授权专利10项，其中发明专利4项，主持科研项目16项，参与973项目一项，培育成功了软体部黑色素含量高的牡蛎新品系并发现了快速生长新品系的选育方法；
入选泰山****青年专家和山东省有突出贡献的中青年专家，兼任山东省现代农业产业技术体系贝类育种岗位专家、上海海洋大学研究生导师，曾获山东省青年科技奖、山东省自然科学学术创新奖和山东省海洋与渔业科学技术奖；
指导学生获得山东省研究生优秀科技创新成果奖、山东省优秀学位论文奖、“挑战杯”大学生课外学术科技作品竞赛山东省一等奖、山东省大学生科技创新大赛一等奖。曾挂职乳山市人民政府副市长。
学习和工作经历：
1998.09-2002.07 山东农业大学 学士 动物科学
2002.09-2005.07 云南农业大学 硕士 动物遗传育种与繁殖
2005.09-2008.06 中国农业大学 博士 动物遗传育种与繁殖
2008.07-2008.12 湖南农业大学 讲师 动物遗传育种与繁殖
2008.12-2011.07 中科院海洋所 博后 贝类遗传育种
2011.07-2012.12 中科院海洋所 助研 贝类遗传育种
2012.12-2015.12 鲁东大学 副教授 贝类遗传育种
2015.12-至今 鲁东大学 教授 贝类遗传育种

主持科研项目：
主持国家自然科学基金面上项目、国家自然科学基金青年项目、国家重点研发计划子课题、国家自然科学基金重大研究计划子课题、863计划子课题、山东省重点研发计划、山东省自然科学基金、山东省现代农业技术产业体系岗位专家项目、国家博士后科学基金等项目10余项。

文章：
(1) Zhang G, X Fang, X Guo, L Li, R Luo, F Xu, P Yang, L Zhang, X Wang(共同第一作者), H Qi, Z Xiong, H Que, Y Xie, P Holland, J Paps, Y Zhu, F Wu, Y Chen, J Wang, C Peng, J Meng, L Yang, J Liu, B Wen, N Zhang, Z Huang, Q Zhu, Y Feng, A Mount, D Hedgecock, Z Xu, Y Liu, T Domazet-Loso, Y Du, X Sun, S Zhang, B Liu, P Cheng, X Jiang, J Li, D Fan, W Wang, W Fu, T Wang, B Wang, J Zhang, Z Peng, Y Li, N Li, J Wang, M Chen, Y He, F Tan, X Song, Q Zheng, R Huang, H Yang, X Du, i Chen, M Yang, P Gaffney, S Wang, L Luo, Z She, Y Ming, W Huang, S Zhang, B Huang, Y Zhang, T Qu, P Ni, G Miao, J wang, Q Wang, C Steinberg, H Wang, N Li, L Qian, G Zhang, Y Li, H Yang, X Liu, J Wang, Y Yin, J Wang. The oyster genome reveals stress adaptation and complexity of shell formation. Nature. 490 (7418): 49-54, 2012.
(2) Wenchao Yu, Cheng He, Zhongqiang Cai , Fei Xu, Lei Wei , Jun Chen, Qiuyun Jiang, Na Wei , Zhuang Li , Wen Guo and Xiaotong Wang*(通讯作者). A Preliminary Study on the Pattern, the Physiological Bases and the Molecular Mechanism of the Adductor Muscle Scar Pigmentation in Pacific Oyster Crassostrea gigas. Frontiers in Physiology. 2017, 9(8), doi: 10.3389/fphys.2017.00699.
(3) Lei Wei, Fei Xu, Yuzhi Wang, Zhongqiang Cai, Wenchao Yu, Cheng He, Qiuyun Jiang, Xiqiang Xu, Wen Guo, and Xiaotong Wang*(通讯作者). The Molecular Differentiation of Anatomically Paired Left and Right Mantles of the Pacific Oyster Crassostrea gigas. Marine Biotechnology. 2018, 20 (4): 425-435. DOI: 10.1007/s10126-018-9806-8.
(4) Changlu Wu, Qiuyun Jiang, Lei Wei, Zhongqiang Cai, Jun Chen, Wenchao Yu, Cheng He, Jiao Wang, Wen Guo and Xiaotong Wang*(通讯作者). A Rhodopsin-Like Gene May Be Associated With the Light-Sensitivity of Adult Pacific Oyster Crassostrea gigas. Frontiers in Physiology. 2018, 9(221), doi: 10.3389/fphys.2018.00221.
(5) Xiaotong Wang, Rui Wang, Yanfeng Zhang, Hao Zhang. Evolutionary survey of druggable protein targets with respect to their subcellular localizations. Genome Biology and Evolution. 2013, 5(7): 1291-1297.
(6) Xiaotong Wang, Qiye Li, Jinmin Lian, Li Li, Lijun Jin, Huimin Cai, Fei Xu, Haigang Qi, Linlin Zhang, Fucun Wu, Jie Meng, Huayong Que, Xiaodong Fang, Ximing Guo, and Guofan Zhang. Genome-wide and single-base resolution DNA methylomes of the Pacific oyster Crassostrea gigas provide insight into the evolution of invertebrate CpG methylation, BMC Genomics, 2014, 15:1119. doi:10.1186/1471-2164-15-1119.
(7) Jun Chen, Changlu Wu, Baolu Zhang, Zhongqiang Cai, Lei Wei, Zhuang Li,Guangbin Li, Ting Guo, Yongchuan Li, Wen Guo and Xiaotong Wang^?(通讯作者). PiggyBac Transposon-Mediated Transgenesis in the Pacific Oyster (Crassostrea gigas) – First Time in Mollusks. Frontiers in Physiology.2018, 9(811), doi: 10.3389/fphys.2018.00811
(8) Xiaotong Wang, Li Li, Yabin Zhu,Yishuai Du,Xiaorui Song, Yuanxin Chen, Ronglian Huang, Huayong Que, Xiaodong Fang and Guofan Zhang. Oyster shell proteins originate from multiple organs and their probable transport pathway to the shell formation front. PLoS ONE. 2013, 8(6), e66522.
(9) Jiao Wang, Changlu Wu, Caili Xu, WenChao Yu, Zhuang Li, Yongchuan Li, Ting Guo, Xiaotong Wang^?(通讯作者).Voltage-gated potassium ion channel may play a major role in the settlement of Pacific oyster (Crassostrea gigas) larvae. Aquaculture, 2015, 442: 48–50.
(10) Changlu Wu , Jiao Wang , Yanjian Yang, Zhuang Li, Ting Guo, Yongchuan Li, Xiaotong Wang*(通讯作者). Adult Pacific Oyster (Crassostrea gigas) May Have Light Sensitivity. PLoS ONE. 2015, 10(10):e**. doi: 10.1371/journal.pone.**.
(11) Shixin Hao, Xin Hou, Lei Wei, Jian Li, Zhonghu Li, Xiaotong Wang* (通讯作者). Extraction and identification of the pigment in the adductor muscle scar of Pacific oyster Crassostrea gigas. PLoS ONE. 2015, 10(11): e**. doi:10.1371/journal.pone.**.
(12)Xiaotong Wang, Li Li, Yabing Zhu,Xiaorui Song, Xiaodong Fang, Ronglian Huang, Huayong Que & Guofan Zhang. Aragonite shells are more ancient than calcite ones in bivalves: new evidence based on omics. Molecular Biology Reports. 2014, 41(11):7067-71.
(13) XT Wang, Zhang YF, Wu Q and Zhang H. 2012. Evolutionary landscape of amphibians emerging from ancient freshwater fish inferred from complete mitochondrial genomes. Biochemical and biophysical research communications. 421(2): 228–231.
(14) Xiaotong Wang, Li Li, Fei Xu, Guofan Zhang. 2011. Tropomyosin is a nice marker gene for phylogenetic analysis of molluscs. Molecular biology reports. 38(7): 4589-4593.
(15) X. T. Wang, C. J. Zhao, J. Y. Li, G. Y. Xu, L. S. Lian, C. X. Wu, and X. M. Deng. 2009. Comparison of the total amount of eggshell pigments in Dongxiang brown-shelled eggs and Dongxiang blue-shelled eggs. Poultry Science, 88: 1735-1739.
(16)X.-T. Wang, X.-M. Deng, C.-J. Zhao, J.-Y. Li, G.-Y. Xu, L.-S. Lian, and C.-X. Wu. 2007. Study of the Deposition Process of Eggshell Pigments Using an Improved Dissolution Method. Poultry Science. 86(10): 2236-2238.
(17) Xiaotong Wang, Xiaorui Song, Tong Wang, Qihui Zhu, Guoying Miao, Yuanxin Chen, Xiaodong Fang, Huayong Que, Li Li, Guofan Zhang. 2013. Evolution and functional analysis of the Pif97 gene of the Pacific oyster (Crassostrea gigas). Current Zoology. 59(1): 109-115.
(18) X.-T. Wang, J.-R. Bai, C.-J. Zhao, H. Zhang, H.-G. Bao, G.-Y. Xu, J.-Y. Li, L.-S. Lian, C.-X. Wu, X.-M. Deng. 2010. Localization of the genomic sequence interval for blue eggshell gene using an F2 resource population of Dongxiang Chicken. British Poultry Science. 51: 507-509.
(19) Qiuyun Jiang, Lei Wei, Chaowei Gai, Wenchao Yu, Cheng He, Man Chen, Zhen Zhang, Hongce Song, Xiaona Wang, and Xiaotong Wang^?(通讯作者). An improved extraction method reveals varied DNA content in different parts of the shells of Pacific oysters. Aquatic Living Resources. 2019, 32, 5, 1-7.
(20) X.-T. Wang, H. Zhang, C.-J. Zhao, J.-Y. Li, G.-Y. Xu, L.-S. Lian, C.-X. Wu, X.-M. Deng. 2009. Cloning of Chicken Microsomal Glutathione S-transferase 1 Gene (MGST1) and Identification of Its Different Splice Variants. Asian-Australasian Journal of Animal Sciences. 22(2): 155-161.
(21) Wang X*., Liu T., Liu Y., Feng P., 2014. An arithmetic index based on shell height, length and width for potential selection of soft-body wet weight in Pacific oyster, Crassostrea gigas, 4 pages. The Israeli Journal of Aquaculture - Bamidgeh, 2014, MS IJA_66.2014.1067.
(22) X.T. Wang, C.J. Zhao, J.Y. Li, G.Y. Xu, L.S. Lian, C.X. Wu and X.M. Deng. 2010. Heme oxygenase-1 is important to the formation of eggshell biliverdin in chicken. Journal of Applied Animal Research. 38(2), 229-232.
(23) Xiaotong Wang, Li Li, Fei Xu, Guofan Zhang. 2011. Genomic DNA Extraction from in vivo Sampled Tissue of Pacific Oyster, Crassostrea gigas. The Israeli Journal of Aquaculture-Bamidgeh. IIC: 63.2011.671.
(24) Xiaotong Wang, Xiaorui Song, Li Li, and Guofan Zhang. 2012. An improved method of DNA extraction from the shell of the Pacific oyster, Crassostrea gigas. The Israeli Journal of Aquaculture-Bamidgeh. IJA_64.2012.800.
(25) Zhuang Li, Lei Wei, Zhongqiang Cai, Jiarong Li, Man Chen, Guangbin Li, Chaowei Gai, Wen Guo, and Xiaotong Wang* (通讯作者). Novel Device and Method for Fast Water Change in the Hatchery Culture of Pacific Oyster Larvae. The Philippine Agricultural Scientist. 2018, 101(3): 278-282.
(26) Li XX, Yu WC, Cai ZQ, He C, Wei N, Wang XT* (通讯作者), Yue XQ. Molecular Cloning and Characterization of Full-Length cDNA of Calmodulin Gene from Pacific Oyster Crassostrea gigas. BioMed Research International. 2016: **.
(27) Wang, Xiaotong，Li, Li，Zhang, Guofan. The dna replication and repair pathway of pacific oyster, crassostrea gigas. Journal of Shellfish Research, 30: 561-561.
(28)Xiaorui Song, Xiaotong Wang, Li Li, Guofan Zhang. Identification two novel nacrein-like proteins involved in the shell formation of the Pacific oyster Crassostrea gigas. Molecular Biology Reports, 2014, 41(7): 4273-8. (2013 IF: 2.506) (共同第一作者)
(29)Hao Zhang, Xiaotong Wang, Yangzom Chamba, Yao Ling, Changxin Wu. 2008. Influences of Hypoxia on Hatching Performance in Chickens with Different Genetic Adaptation to High Altitude. Poultry Science. 87: 2112-2116. (共同第一作者)
(30)Zhang Q, Gou W, Wang X, Zhang Y, Ma J, Zhang H, Zhang Y, Zhang H. Genome Resequencing Identifies Unique Adaptations of Tibetan Chickens to Hypoxia and High-Dose Ultraviolet Radiation in High-Altitude Environments. Genome Biology Evolution. 2016, 8(3):765-76. doi: 10.1093/gbe/evw032. (共同第一作者)
(31)Fei Xu, Xiaotong Wang, Yue Feng, Wen Huang, Wei Wang, Li Li, Xiaodong Fang, Huayong Que, Guofan Zhang. 2014. Identification of Conserved and Novel MicroRNAs in the Pacific Oyster Crassostrea gigas by Deep Sequencing. PLoS ONE. DOI: 10.1371/journal.pone.**.
(32)Z.P. Wang, X.T. Wang, R.F Liu, J.Y. Li and X.M. Deng, 2010. Refined Localization of the O Gene for Blue Egg Phenotype on Chicken Chromosome 1. Journal of Animal and Veterinary Advances, 9: 2947-2950.
(33)Z.P. Wang, X.T. Wang, R.F. Liu, A.R. Wang, J.Y. Li and X.M. Deng, 2011. Discover of a Novel SNP Highly Associated with Chicken Blue Egg. Journal of Animal and Veterinary Advances, 10: 92-95.
(34)B. Yu, X.T. Wang, H.W. Li, C.J. Zhao, C.X. Wu and X.M. Deng. 2011. Structural analysis of a 4414-bp element in Drosophila melanogaster. Genetics and Molecular Research 10(2): 717-730.
(35) Linlin Zhang, Li Li, Fei Xu, Haigang Qi, Xiaotong Wang, Huayong Que & Guofan Zhang. 2012. Fosmid library construction and end sequences analysis of the Pacific oyster, Crassostrea gigas. Molluscan Research. 33(1): 65-73.
(36) Zhang G F, Guo X M, Li L, Xu F, Wang X T, Qi H G, Zhang L L, Que H Y, Wu H G, Wang S H, Hedgecock D, Gaffney P M, Luo R B, Fang X D, Wang J. 2011. The oyster genome project: an update on assembly and annotation. Journal of Shellfish Research, 30: 567-567.
(37)Zhepeng Wang, Lujiang Qu, Junfeng Yao, Xiaolin Yang, Guangqi Li, Yuanyuan Zhang, Junying Li, Xiaotong Wang, Jirong Bai, Guiyun Xu, Xuemei Deng, Ning Yang, and Changxin Wu. An EAV-HP Insertion in 5' Flanking Region of SLCO1B3 Causes Blue Eggshell in the Chicken. PLoS Genetics. 2013, 9(1): e**.
(38)王晓通, 连林生, 赵春江, 邓学梅, 吴常信. 非变性聚丙烯酰胺凝胶电泳中与杂合子相伴产生的非目的条带的鉴定. 农业生物技术学报. 2010, 18(3): 616-622.
(39)王晓通，娄义洲. 武定鸡绿壳蛋系蛋壳色素的研究. 中国家禽. 2006, 28(14): 14-16.
(40)徐彩丽，许飞，王娇，武长路，于文超，王晓通（通讯作者）. 牡蛎幼虫光照实验提示了复杂遗传背景下基因互作的多样性. 海洋与湖沼. 2015, 46（3）：571-576.
(41)于文超，何成，武长路，王娇，李壮，郭婷，李永川，王晓通（通讯作者）. 长牡蛎贝壳与外套膜中黑色素的提取和鉴定. 海洋与湖沼. 2015, 46（4）：909-914.
(42)何成，于文超，蔡忠强，魏磊，陈军，李佳荣，盖超伟，李壮，张子豪，郭文，王晓通（通讯作者）. 酸碱粗提配合超声破碎法制取可溶性长牡蛎(Crassostrea gigas)黑色素的研究. 海洋与湖沼. 2017，48(3)：635-640.(43)郝世鑫，侯鑫，孙东方，于文超，何成，王晓通（通讯作者）. 紫贻贝贝壳和脉红螺厣中色素的提取与鉴定. 海洋科学. 2015, 39（11）：49-53.
(44) 何 成,于文超,蔡忠强,魏磊,陈军,李佳荣,盖超伟,姜秋云,孙杰,王晓安,郭文,王晓通（通讯作者）. 长牡蛎可溶性黑色素的脱盐研究. 海洋科学. 2017, 41（11）：97-101.