Song, Yin-Ping1; Ji, Nai-Yun1
; Shi, Xiao-Shan2; Wang, Bin-Gui2发表期刊FITOTERAPIA
ISSN0367-326X
2020-10
卷号146页码:104715
关键词Trichoderma virensSesquiterpeneCadinaneCarotane
DOI10.1016/j.fitote.2020.104715
英文摘要Eight cadinane derivatives, trichocadinins H - N (1-7) and methylhydroheptelidate (8), and two carotane derivatives, 14-O-methyltrichocarotin G (9) and 14-O-methyl CAF-603 (10), including eight new ones (1-6, 9, and 10), were isolated from the culture of Trichoderma virens RR-dl-6-8 obtained from the organohalogen-enriched marine red alga Rhodomela confervoides. Their structures and relative configurations were established by analysis of NMR and mass spectroscopic data, and the absolute configurations were assigned on the basis of ECD curves, highlighted by the ECD diversity of carboxylic acid derivatives. Among the isolates, 1 with a halogen atom and 8, a new naturally occurring compound, are 2,3-seco-cadinane sesquiterpenes, and the epimeric 2 and 3 feature a 2-nor-cadinane skeleton. A commercially-sourced compound with the same planar structure as that of 7 has been reported in a patent, but its configuration was not given. Compounds 1-10 exhibited growth inhibition of some marine phytoplankton species.
资助机构Natural Science Foundation for Distinguished Young Scholars of Shandong Province [JQ201712]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31670355]; Youth Innovation Promotion Association of the CAS [Y201734]; Shuangbai Plan of Yantai [2018-3]; Taishan Scholar Project Special Funding [tsqn201909164]
收录类别SCI
语种英语
关键词[WOS]SECONDARY METABOLITES
研究领域[WOS]Pharmacology & Pharmacy
WOS记录号WOS:000580427700061
引用统计被引频次：3[WOS][WOS记录][WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/30494
专题海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
作者单位1.Chinese Acad Sci, Ctr Ocean Megasci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China;
2.Chinese Acad Sci, Ctr Ocean Megasci, Inst Oceanol,Key Lab Expt Marine Biol, Lab Marine Biol & Biotechnol,Qingdao Natl Lab Mar, Qingdao 266071, Peoples R China
推荐引用方式
GB/T 7714Song, Yin-Ping,Ji, Nai-Yun,Shi, Xiao-Shan,et al. Cadinane and carotane derivatives from the marine algicolous fungus Trichoderma virens RR-dl-6-8[J]. FITOTERAPIA,2020,146:104715.
APASong, Yin-Ping,Ji, Nai-Yun,Shi, Xiao-Shan,&Wang, Bin-Gui.(2020).Cadinane and carotane derivatives from the marine algicolous fungus Trichoderma virens RR-dl-6-8.FITOTERAPIA,146,104715.
MLASong, Yin-Ping,et al."Cadinane and carotane derivatives from the marine algicolous fungus Trichoderma virens RR-dl-6-8".FITOTERAPIA 146(2020):104715.
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