李金花1
; 王艺晓1,2; 王莉燕1,2,3; 陈令新1发表期刊海岸科学
2019-08-29
卷号6期号:2页码:8-21
关键词磺胺类抗生素分子印迹聚合物样品前处理固相萃取印迹技术印迹策略
研究领域分子印迹聚合物新材料的制备及其在环境污染物检测应用方
英文摘要The residues of sulfonamides (SAs) antibiotics cause great harm to organisms and environments. Appropriate sample pretreatment is usually imperative to couple with chromatography / mass spectrometry analysis for the sensitive determination of SAs, owing to their low level residues and multiple categories presence in complicated matrices. Molecularly imprinted polymers (MIPs) have the binding sites complementary to the template molecules in shape, size and functional groups. So, MIPs can selectively recognize and effectively enrich target analytes (template) as well as eliminate matrices interferences. Thereby they have been widely applied in the sample pretreatment of SAs antibiotics. In this review, recent advances in sample pretreatment applications of MIPs for determination of SAs residues are summarized, mainly including conventional packed solid-phase extraction (PSPE), dispersive solid-phase extraction (DSPE), magnetic solid-phase extraction (MSPE) and temperature sensitive solid-phase extraction (TSPE). Several challenge issues of MIPs are given, and some new imprinting technologies and strategies for preparation of MIPs towards SAs are highlighted, such as surface imprinting technology, nanoimprinting technology and molecularly imprinted membrane technology, as well as multi-template imprinting strategy and dummy imprinting strategy. Finally, an outlook on the preparation and pretreatment application of SAs-MIPs is proposed.
中文摘要磺胺类(Sulfonamides,SAs)抗生素残留极大危害生物体和环境,其含量低、种类多、基质复杂,通常需要进 行样品前处理结合色谱/ 质谱分析以实现灵敏检测。 分子印迹聚合物(Molecularly imprinted polymers,MIPs)是具有与 模板分子在形状、大小及官能团完全匹配的特异性识别位点的高分子聚合物,能选择性识别和富集目标分析物(模板 分子)并消除干扰,已广泛用于 SAs 的样品前处理。 本文综述了 MIPs 在 SAs 残留检测中的样品前处理应用,主要包括 装柱固相萃取、分散固相萃取、磁固相萃取、温敏性固相萃取等,总结了 MIPs 制备中面临的挑战,重点介绍了制备 SAs -MIPs 的印迹新技术和新策略,如表面印迹技术、纳米印迹技术、分子印迹膜技术,多模板印迹策略、虚拟模板印迹策 略等。 最后,展望了 SAs-MIPs 的制备和前处理应用。
语种中文
关键词[WOS]Sulfonamides antibiotics; Molecularly imprinted polymers; Sample pretreatment; Solid phase extraction; Imprinting technology; Imprinting strategy
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/29809
专题《海岸科学》
中科院海岸带环境过程与生态修复重点实验室
通讯作者李金花作者单位1.中国科学院海岸带环境过程与生态修复重点实验室(烟台海岸带研究所),海岸带环境工程技术研究与发展中心;
2.中国科学院大学;
3.烟台工程职业技术学院
推荐引用方式
GB/T 7714李金花,王艺晓,王莉燕,等. 分子印迹聚合物在磺胺类抗生素残留检测中的 样品前处理应用研究进展[J]. 海岸科学,2019,6(2):8-21.
APA李金花,王艺晓,王莉燕,&陈令新.(2019).分子印迹聚合物在磺胺类抗生素残留检测中的 样品前处理应用研究进展.海岸科学,6(2),8-21.
MLA李金花,et al."分子印迹聚合物在磺胺类抗生素残留检测中的 样品前处理应用研究进展".海岸科学 6.2(2019):8-21.
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