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Synthesis and antioxidant activity of the inulin derivative bearing 1,2,3-triazole and diphenyl phos

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Synthesis and antioxidant activity of the inulin derivative bearing 1,2,3-triazole and diphenyl phosphate
Wei, Lijie1,2,3; Sui, Haishan1; Zhang, Jingjing2,3; Guo, Zhanyong2,3,4
发表期刊INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
ISSN0141-8130
2021-09-01
卷号186页码:47-53
关键词Inulin derivativeAntioxidant activityCuAAC Click chemistry
DOI10.1016/j.ijbiomac.2021.06.148
通讯作者Guo, Zhanyong(zhanyongguo@hotmail.com)
英文摘要In this paper, the inulin derivative (3) bearing 1,2,3-triazole and diphenyl phosphate was successfully synthesized by CuAAC Click chemistry. Detailed structural characterization was determined using FTIR spectroscopy, H-1 NMR spectroscopy, C-13 NMR spectroscopy, and elemental analysis. The antioxidant activities against hydroxyl radicals, superoxide radicals, and DPPH radicals were estimated in vitro respectively. The results showed that the antioxidant activity of the inulin derivative (3) was significantly enhanced compared with inulin. The inulin derivative (3) exhibited stronger radical scavenging abilities, especially against hydroxyl radicals and superoxide radicals. The scavenging values of the inulin derivative (3) were 98.2% and 95.4% at 1.6 mg/mL against hydroxyl radicals and superoxide radicals respectively. Besides, the scavenging value of the inulin derivative (3) increased by about 40% to scavenge DPPH radicals at 1.6 mg/mL than inulin. The results showed that the inulin derivative (3) bearing 1,2,3-triazole and diphenyl phosphate exhibited tremendously enhanced antioxidant activity compared with inulin. The synthetic strategy might provide an effective way to prepare novel inulin antioxidant biomaterials.
资助机构Youth Innovation Promotion Association CAS; Natural Science Foundation of Shandong Province of China; National Key Research and Development Pro-gram of China; Natural Science Foundation of Shandong Province Science and Technology Development Plan
收录类别SCI
语种英语
关键词[WOS]REACTIVE OXYGEN; CHITOSAN DERIVATIVES; ANTIFUNGAL ACTIVITY; SCAVENGING ACTIVITY; CLICK CHEMISTRY; PHOSPHORYLATION; COPOLYMERS; NITROGEN; STRESS
研究领域[WOS]Biochemistry & Molecular Biology; Chemistry; Polymer Science
WOS记录号WOS:000688432800006
引用统计
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/29704
专题海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心
海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室

通讯作者Guo, Zhanyong作者单位1.Weifang Adm Market Regulat, Weifang Inspect & Testing Ctr, Weifang 261000, Shandong, Peoples R China
2.Chinese Acad Sci, Key Lab Coastal Biol & Bioresource Utilizat, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
4.Chinese Acad Sci, Ctr Ocean Mega Sci, 7 Nanhai Rd, Qingdao 266071, Peoples R China

推荐引用方式
GB/T 7714Wei, Lijie,Sui, Haishan,Zhang, Jingjing,et al. Synthesis and antioxidant activity of the inulin derivative bearing 1,2,3-triazole and diphenyl phosphate[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2021,186:47-53.
APAWei, Lijie,Sui, Haishan,Zhang, Jingjing,&Guo, Zhanyong.(2021).Synthesis and antioxidant activity of the inulin derivative bearing 1,2,3-triazole and diphenyl phosphate.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,186,47-53.
MLAWei, Lijie,et al."Synthesis and antioxidant activity of the inulin derivative bearing 1,2,3-triazole and diphenyl phosphate".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 186(2021):47-53.


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