Wang, Lei
; Li, Wenjun; Qin, Song发表期刊POLYMERS
2021-08-01
卷号13期号:15页码:18
关键词alginatechitosancollagenbiomaterialstissue engineering
DOI10.3390/polym13152482
通讯作者Qin, Song(sqin@yic.ac.cn)
英文摘要With the increase of wounds and body damage, the clinical demand for antibacterial, hemostatic, and repairable biomaterials is increasing. Various types of biomedical materials have become research hotspots. Of these, and among materials derived from marine organisms, the research and application of alginate, chitosan, and collagen are the most common. Chitosan is mainly used as a hemostatic material in clinical applications, but due to problems such as the poor mechanical strength of a single component, the general antibacterial ability, and fast degradation speed research into the extraction process and modification mainly focuses on the improvement of the above-mentioned ability. Similarly, the research and modification of sodium alginate, used as a material for hemostasis and the repair of wounds, is mainly focused on the improvement of cell adhesion, hydrophilicity, degradation speed, mechanical properties, etc.; therefore, there are fewer marine biological collagen products. The research mainly focuses on immunogenicity removal and mechanical performance improvement. This article summarizes the source, molecular structure, and characteristics of alginate, chitosan, and collagen from marine organisms; and introduces the biological safety, clinical efficacy, and mechanism of action of these materials, as well as their extraction processes and material properties. Their modification and other issues are also discussed, and their potential clinical applications are examined.
资助机构Department of Science and Technology of Shandong Province
收录类别SCI
语种英语
关键词[WOS]MORPHOGENETIC PROTEIN-2 DELIVERY; OXIDIZED ALGINATE; SODIUM ALGINATE; ARTIFICIAL CORNEA; COLLAGEN SPONGE; CARBON-DIOXIDE; FISH COLLAGEN; STEM-CELLS; CHITOSAN; BONE
研究领域[WOS]Polymer Science
WOS记录号WOS:000682171400001
引用统计
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/29625
专题海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
通讯作者Qin, Song作者单位Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Biol & Bioresource Utilizat, Yantai 264003, Peoples R China
推荐引用方式
GB/T 7714Wang, Lei,Li, Wenjun,Qin, Song. Three Polymers from the Sea: Unique Structures, Directional Modifications, and Medical Applications[J]. POLYMERS,2021,13(15):18.
APAWang, Lei,Li, Wenjun,&Qin, Song.(2021).Three Polymers from the Sea: Unique Structures, Directional Modifications, and Medical Applications.POLYMERS,13(15),18.
MLAWang, Lei,et al."Three Polymers from the Sea: Unique Structures, Directional Modifications, and Medical Applications".POLYMERS 13.15(2021):18.
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