Wei, Lijie1,2,3; Zhang, Jingjing1,2; Tan, Wenqiang1,2
; Wang, Gang1,2; Li, Qing1,2; Dong, Fang1,2; Guo, Zhanyong1,2,4发表期刊INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
ISSN0141-8130
2021-05-15
卷号179页码:292-298
关键词Antifungal activityChitosan derivativesSchiff base
DOI10.1016/j.ijbiomac.2021.02.184
通讯作者Zhang, Jingjing(jingjingzhang@yic.ac.cn); Guo, Zhanyong(zhanyongguo@hotmail.com)
英文摘要In this study, a series of chitosan derivatives bearing active halogenated aromatic imines were successfully synthesized via Schiff bases with the high degrees of substitution. Detailed structural characterization was carried out using Fourier transform infrared (FTIR) spectroscopy, solid-state C-13 nuclear magnetic resonance (NMR) spectroscopy, and elemental analysis. Besides, the antifungal activity against three common plant pathogenic fungi, including Botrytis cinerea, Fusarium oxysporum f. sp. cucumerinum, and Fusarium oxysporum f. sp. niveum, was investigated using in vitro hyphal measurements. The results showed that double Schiff bases of chitosan derivatives exhibited enhanced antifungal activity compared with chitosan, especially at 1.0 mg/mL. The double Schiff bases of chitosan bearing halogeno-benzenes showed >95% inhibitory indices at 1.0 mg/mL against Botrytis cinereal since halogens had the stronger electron-withdrawing property. The higher degree of substitution was another positive effect to improve the antifungal activity. This study provides a practical strategy to synthesize new double Schiff bases of chitosan derivatives bearing halogeno-benzenes, which could be developed into stronger antifungal agents. (C) 2021 Elsevier B.V. All rights reserved.
资助机构Youth Innovation Promotion Association CAS; Natural Science Foundation of Shandong Province of China; National Key Research and Development Program of China; Natural Science Foundation of Shandong Province Science and Technology Development Plan
收录类别SCI
语种英语
关键词[WOS]ANTIMICROBIAL ACTIVITY; ANTIBACTERIAL ACTIVITY; BIOLOGICAL-ACTIVITY; INULIN DERIVATIVES; ANTIOXIDANT; FILMS
研究领域[WOS]Biochemistry & Molecular Biology; Chemistry; Polymer Science
WOS记录号WOS:000645619000008
引用统计被引频次：2[WOS][WOS记录][WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/29334
专题海岸带生物学与生物资源利用重点实验室
海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
中科院海岸带环境过程与生态修复重点实验室_海岸带环境过程实验室
海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心
通讯作者Zhang, Jingjing; Guo, Zhanyong作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China
2.Chinese Acad Sci, Ctr Ocean Megasci, 7 Nanhai Rd, Qingdao 266071, Peoples R China
3.Weifang Inspect & Testing Ctr, Weifang 261000, Shandong, Peoples R China
4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714Wei, Lijie,Zhang, Jingjing,Tan, Wenqiang,et al. Antifungal activity of double Schiff bases of chitosan derivatives bearing active halogeno-benzenes[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2021,179:292-298.
APAWei, Lijie.,Zhang, Jingjing.,Tan, Wenqiang.,Wang, Gang.,Li, Qing.,...&Guo, Zhanyong.(2021).Antifungal activity of double Schiff bases of chitosan derivatives bearing active halogeno-benzenes.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,179,292-298.
MLAWei, Lijie,et al."Antifungal activity of double Schiff bases of chitosan derivatives bearing active halogeno-benzenes".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 179(2021):292-298.
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