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Synthesis and Characterization of Inulin Butyrate Ester, and Evaluation of Its Antioxidant Activity

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Synthesis and Characterization of Inulin Butyrate Ester, and Evaluation of Its Antioxidant Activity and In Vitro Effect on SCFA Production
Zhu, Xiaozhen1,2; Zhang, Xia1,2; Gao, Xuelu2,3; Meng, Xianyao1,2; Yi, Yuetao1,4
发表期刊STARCH-STARKE
ISSN0038-9056
2020-06-22
页码9
关键词antioxidant activitydegree of substitutioninulininulin butyrate estersshort-chain fatty-acids
DOI10.1002/star.201900323
通讯作者Yi, Yuetao(ytyi@yic.ac.cn)
英文摘要The aim of this study is to develop a method for the synthesis of inulin butyrate ester (IBE) as a short chain fatty acid (SCFA) delivery carrier. Inulin is modified by butyric anhydride and the structure is characterized by Fourier Transform Infrared and(1)H NMR. On this basis, the synthetic conditions are optimized with response surface methodology (RSM) to investigate the effects of three parameters (the ratio of anhydride to inulin, inulin concentration, and reaction temperature) on the degree of substitution (DS). Under the optimal conditions, the actual experimental DS is 2.59 +/- 0.14. The antioxidant activities of inulin and IBE are determined by superoxide anion radical and hydroxyl radical scavenging ability. The results show that the butyrylation inulin increases antioxidant activities and indicate that IBE could be used as a potential antioxidant. In a 36 h in vitro fermentation experiment, IBE is shown to increase the total SCFA content and the butyrate ratio, which illustrates that IBE could be used as SCFA carrier for delivering high concentration of SCFA to the colon, and thus influencing intestinal health.
资助机构National Key Research & Development Program in China; Science and Technology Service Initiative of the Chinese Academy of Sciences; Key Research and Development Program of Yantai
收录类别SCI
语种英语
关键词[WOS]CHAIN FATTY-ACIDS; ANTIBACTERIAL ACTIVITIES; ENCAPSULATION MATERIAL; CYCLOCARYA-PALIURUS; POLYSACCHARIDE; MICROBIOTA; OLIGOSACCHARIDES; CONSEQUENCES; FRUCTANS; SELF
研究领域[WOS]Food Science & Technology
WOS记录号WOS:000541553600001
引用统计
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/28688
专题海岸带生物学与生物资源利用重点实验室
海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
中科院海岸带环境过程与生态修复重点实验室

通讯作者Yi, Yuetao作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Chinese Acad Sci, Yantai Inst Coastal Zone Res, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China
4.Chinese Acad Sci, Ctr Ocean Mega Sci, 7 Nanhai Rd, Qingdao 266071, Peoples R China

推荐引用方式
GB/T 7714Zhu, Xiaozhen,Zhang, Xia,Gao, Xuelu,et al. Synthesis and Characterization of Inulin Butyrate Ester, and Evaluation of Its Antioxidant Activity and In Vitro Effect on SCFA Production[J]. STARCH-STARKE,2020:9.
APAZhu, Xiaozhen,Zhang, Xia,Gao, Xuelu,Meng, Xianyao,&Yi, Yuetao.(2020).Synthesis and Characterization of Inulin Butyrate Ester, and Evaluation of Its Antioxidant Activity and In Vitro Effect on SCFA Production.STARCH-STARKE,9.
MLAZhu, Xiaozhen,et al."Synthesis and Characterization of Inulin Butyrate Ester, and Evaluation of Its Antioxidant Activity and In Vitro Effect on SCFA Production".STARCH-STARKE (2020):9.


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