Wang, Jiangru1; Chen, Xiaolan1
; Wang, Xiaoyan2; Kang, Qi1; Shen, Dazhong1; Chen, Lingxin3发表期刊SENSORS AND ACTUATORS B-CHEMICAL
2020-11-01
卷号322页码:9
关键词Molecular imprintingRatiometric fluorescenceDifferential measurementSmartphoneBovine hemoglobin
DOI10.1016/j.snb.2020.128581
通讯作者Shen, Dazhong(dzshen@sdnu.edu.cn); Chen, Lingxin()
英文摘要The non-specific adsorption of interferents onto the outside surface of molecularly imprinted polymers (MIPs) particles is disadvantageous for selective determination of the template molecules. Based on the fact that the responses of non-imprinted polymers (NIPs) and MIPs particles to non-template molecules are similar, the anti-interference ability of MIPs sensor can be much improved via differential strategy, demonstrated by bovine hemoglobin (BHb) determination. The MIPs for BHb were prepared via surface imprinting and sol-gel process, with graphene quantum dots@SiO2/CdTe quantum dots (GODs@SiO2/CdTe QDs) for ratiometric fluorescence measurements. By using a weight factor of 1.283 to compensate the lower specific surface area in NIPs particles, the differential ratiometric fluorescence signals between MIPs and NIPs channels to 2.00 mu M ovalbumin and phycocyanin are equivalent to BHb at the concentration of 0.025 and 0.014 mu M, which are only about 11 % and 5.8 % of the interference level in the normal ratiometric fluorescence method, respectively. The differential ratiometric fluorescence measurement was also performed in a smartphone-based device for field analysis of BHb in urine samples, with the linear range of 0.05-4 mu M and the detection limit of 13 nM.
资助机构National Natural Science Foundation of China; Natural Science Foundation of Shandong Province of China; Taishan Scholar Project Special Fund
收录类别SCI
语种英语
关键词[WOS]SELECTIVE RECOGNITION; SENSITIVE DETECTION; QUANTUM DOTS; SMARTPHONE; POLYMERS; NANOPARTICLES; PERFORMANCE
研究领域[WOS]Chemistry; Electrochemistry; Instruments & Instrumentation
WOS记录号WOS:000573296800001
引用统计被引频次：4[WOS][WOS记录][WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/28497
专题中科院海岸带环境过程与生态修复重点实验室_海岸带环境工程技术研究与发展中心
中科院海岸带环境过程与生态修复重点实验室
通讯作者Shen, Dazhong; Chen, Lingxin作者单位1.Shandong Normal Univ, Coll Chem Chem Engn & Mat Sci, Key Lab Mol & Nano Probes, Minist Educ, Jinan 250014, Peoples R China
2.Binzhou Med Univ, Sch Pharm, Yantai 264003, Peoples R China
3.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China
推荐引用方式
GB/T 7714Wang, Jiangru,Chen, Xiaolan,Wang, Xiaoyan,et al. Enhancing anti-interference ability of molecularly imprinted ratiometric fluorescence sensor via differential strategy demonstrated by the detection of bovine hemoglobin[J]. SENSORS AND ACTUATORS B-CHEMICAL,2020,322:9.
APAWang, Jiangru,Chen, Xiaolan,Wang, Xiaoyan,Kang, Qi,Shen, Dazhong,&Chen, Lingxin.(2020).Enhancing anti-interference ability of molecularly imprinted ratiometric fluorescence sensor via differential strategy demonstrated by the detection of bovine hemoglobin.SENSORS AND ACTUATORS B-CHEMICAL,322,9.
MLAWang, Jiangru,et al."Enhancing anti-interference ability of molecularly imprinted ratiometric fluorescence sensor via differential strategy demonstrated by the detection of bovine hemoglobin".SENSORS AND ACTUATORS B-CHEMICAL 322(2020):9.
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