Yu, Deliang1,2,3,8; Peng, Zheng1,2; Wu, Huifeng3,4,5,7
; Zhang, Xiaoying6; Ji, Chenglong3,4,5,7; Peng, Xiao1,2发表期刊ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
ISSN0147-6513
2021-04-01
卷号212页码:8
关键词Mytilus galloprovincialisMicroRNAsCadmiumToxicological effects
DOI10.1016/j.ecoenv.2021.111927
通讯作者Wu, Huifeng(hfwu@yic.ac.cn); Peng, Xiao(pengxiao_px@szu.edu.cn)
英文摘要MicroRNAs (miRNAs) are known to have complicated functions in aquatic species, but little is known about the role of miRNAs in mollusk species under environmental stress. In this study, we performed small RNA sequencing to characterize the differentially expressed miRNAs in different tissues (whole tissues, digestive glands, gills, and gonads) of blue mussels (Mytilus galloprovincialis) exposed to cadmium (Cd). In summary, 107 known miRNAs and 32 novel miRNAs were significantly (p < 0.01) differentially expressed after Cd exposure. The peak size of miRNAs was 22 nucleotides. Target genes of these differentially expressions of miRNAs related to immune defense, apoptosis, lipid and xenobiotic metabolism showed significant changes under Cd stress. These findings provide the first characterization of miRNAs in mussel M. galloprovincialis and expressions of many target genes in response to Cd stress.
资助机构National Natural Science Foundation of China; Shenzhen Basic Research Project; Natural Science Foundation of SZU; Shandong Key Laboratory of Coastal Environmental Processes, YICCAS
收录类别SCI
语种英语
研究领域[WOS]Environmental Sciences & Ecology; Toxicology
WOS记录号WOS:000620097200011
引用统计
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/27400
专题中科院海岸带环境过程与生态修复重点实验室
中科院海岸带环境过程与生态修复重点实验室_海岸带环境过程实验室
通讯作者Wu, Huifeng; Peng, Xiao作者单位1.Shenzhen Univ, Ctr Biomed Opt & Photon CBOP, Shenzhen 518060, Peoples R China
2.Shenzhen Univ, Coll Phys & Optoelect Engn, Key Lab Optoelect Devices & Syst, Shenzhen 518060, Peoples R China
3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Fisheries Sci & Food Prod Proc, Qingdao 266237, Peoples R China
4.YICCAS, Shandong Key Lab Coastal Environm Proc, Yantai 264003, Peoples R China
5.Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, CAS Key Lab Coastal Environm Proc & Ecol Remediat, YICCAS, Yantai 264003, Peoples R China
6.Shenzhen Univ, Hlth Sci Ctr, AstraZeneca Shenzhen Univ Joint Inst Nephrol, Dept Physiol, Shenzhen 518060, Peoples R China
7.Chinese Acad Sci, Ctr Ocean Megasci, Qingdao 266071, Peoples R China
8.Qingdao Natl Lab Marine Sci & Technol, Qingdao 266237, Peoples R China
推荐引用方式
GB/T 7714Yu, Deliang,Peng, Zheng,Wu, Huifeng,et al. Stress responses in expressions of microRNAs in mussel Mytilus galloprovincialis exposed to cadmium[J]. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,2021,212:8.
APAYu, Deliang,Peng, Zheng,Wu, Huifeng,Zhang, Xiaoying,Ji, Chenglong,&Peng, Xiao.(2021).Stress responses in expressions of microRNAs in mussel Mytilus galloprovincialis exposed to cadmium.ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,212,8.
MLAYu, Deliang,et al."Stress responses in expressions of microRNAs in mussel Mytilus galloprovincialis exposed to cadmium".ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 212(2021):8.
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