Fluorescent and Colorimetric Dual-signal Enantiomers Recognition via Enzyme Catalysis: The Case of Glucose Enantiomers Using Nitrogen-doped Silicon Quantum Dots/Silver Probe Coupled with beta-D-Glucose Oxidase
Yi, Yinhui1,3; Liu, Lirong1; Wu, Yuntao1; Zhu, Gangbing1,2,3
发表期刊ANALYTICAL SCIENCES
ISSN0910-6340
2021-02-01
卷号37期号:2页码:275-281
关键词Chiral recognitionchiral sensingenantiomerssilicon quantum dotsfluorescence sensing
DOI10.2116/analsci.20P228
通讯作者Yi, Yinhui(yyh1108@ujs.edu.cn)
英文摘要Chiral enantiomer recognition is important but facing tough challenges in the direct quantitative determination for complex samples. In this work, via chosing nitrogen-doped silicon quantum dots (N-SiQD) as optical nanoprobe and constructing N-SiQD/silver (N-SiQD/Ag NPs) complex, beta-D-GOx as model enzyme and glucose enantiomers as analytes, a fluorescent and colorimetric dual-signal chiral sensing strategy was proposed herein for chiral recognition based on specific enzyme-catalyzed reaction. N-SiQD can exhibit intense fluorescence, while it can be quenched by Ag NPs owing to the formation of N-SiQD/Ag NPs. In the presence of glucose isomer, D-glucose is catalytically hydrolyzed by beta-DGOx to form H2O2 owing to the specific enzyme catalyzed reaction between D-glucose and beta-D-GOx, and H2O2 can etch Ag NPs from the N-SiQD/Ag NPs probe to change the solution color from brown to colorless and restore the N-SiQD fluorescence; while these phenomena cannot be caused by L-glucose, a dual-signal sensing method was thus constructed for recognizing glucose enantiomers. It is believed that the chiral enantiomers recognition strategy via enzyme catalysis has great application for selective and quantificational detection of enantiomers in the complex sample system.
资助机构National Natural Science Foundation of China; Priority Academic Program Development of Jiangsu Higher Education Institutions, Collaborative Innovation Center of Technology and Material of Water Treatment
收录类别SCI
语种英语
关键词[WOS]ENHANCED ENANTIOSELECTIVITY; DOTS; DISCRIMINATION; SENSOR; CYSTEINE; NANOPARTICLES; NANOPROBE; ISOMERS; SYSTEM; ACID
研究领域[WOS]Chemistry
WOS记录号WOS:000618245800007
引用统计被引频次：1[WOS][WOS记录][WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/27388
专题中科院海岸带环境过程与生态修复重点实验室

通讯作者Yi, Yinhui作者单位1.Jiangsu Univ, Sch Environm & Safety Engn, Zhenjiang 212013, Jiangsu, Peoples R China
2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai, Peoples R China
3.Hunan Univ, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China

推荐引用方式
GB/T 7714Yi, Yinhui,Liu, Lirong,Wu, Yuntao,et al. Fluorescent and Colorimetric Dual-signal Enantiomers Recognition via Enzyme Catalysis: The Case of Glucose Enantiomers Using Nitrogen-doped Silicon Quantum Dots/Silver Probe Coupled with beta-D-Glucose Oxidase[J]. ANALYTICAL SCIENCES,2021,37(2):275-281.
APAYi, Yinhui,Liu, Lirong,Wu, Yuntao,&Zhu, Gangbing.(2021).Fluorescent and Colorimetric Dual-signal Enantiomers Recognition via Enzyme Catalysis: The Case of Glucose Enantiomers Using Nitrogen-doped Silicon Quantum Dots/Silver Probe Coupled with beta-D-Glucose Oxidase.ANALYTICAL SCIENCES,37(2),275-281.
MLAYi, Yinhui,et al."Fluorescent and Colorimetric Dual-signal Enantiomers Recognition via Enzyme Catalysis: The Case of Glucose Enantiomers Using Nitrogen-doped Silicon Quantum Dots/Silver Probe Coupled with beta-D-Glucose Oxidase".ANALYTICAL SCIENCES 37.2(2021):275-281.


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