Identification of Growth-Associated Genes by Genome-Wide Association Study and Their Potential Application in the Breeding of Pacific White Shrimp (Litopenaeus vannamei)
Lyu, Ding1,2,3; Yu, Yang1,2,3; Wang, Quanchao1,3,4; Luo, Zheng1,3,5; Zhang, Qian1,3,5; Zhang, Xiaojun1,2,3; Xiang, Jianhai1,3; Li, Fuhua1,2,3,6
发表期刊FRONTIERS IN GENETICS
2021-04-07
卷号12页码:9
关键词GWASgrowth traitmarker assisted BLUPgenetic breedingLitopenaeus vannamei
DOI10.3389/fgene.2021.611570
通讯作者Li, Fuhua(fhli@qdio.ac.cn)
英文摘要The Pacific white shrimp (Litopenaeus vannamei) is the most widely cultured shrimp in the world. A great attention has been paid to improve its body weight (BW) at harvest through genetic selection for decades. Genome-wide association study (GWAS) is a tool to dissect the genetic basis of the traits. In this study, a GWAS approach was conducted to find genes related to BW through genotyping 94,113 single nucleotide polymorphisms (SNPs) in 200 individuals from a breeding population. Four BW-related SNPs located in LG19 and LG39 were identified. Through further candidate gene association analysis, the SNPs in two candidate genes, deoxycytidylate deaminase and non-receptor protein tyrosine kinase, were found to be related with the body weight of the shrimp. Marker-assisted best linear unbiased prediction (MA-BLUP) based on the SNPs in these two genes was used to estimate the breeding values, and the result showed that the highest prediction accuracy of MA-BLUP was increased by 9.4% than traditional BLUP. These results will provide useful information for the marker-assisted breeding in L. vannamei.
资助机构Strategic Priority Research Program of the Chinese Academy of Sciences; National Key R&D Program of China; Agricultural Variety Improvement Project of Shandong Province; China Agriculture Research System-48
收录类别SCI
语种英语
研究领域[WOS]Genetics & Heredity
WOS记录号WOS:000641715100001
引用统计被引频次：1[WOS][WOS记录][WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/27303
专题海岸带生物学与生物资源利用重点实验室

通讯作者Li, Fuhua作者单位1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao, Peoples R China
2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao, Peoples R China
3.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao, Peoples R China
4.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai, Peoples R China
5.Univ Chinese Acad Sci, Beijing, Peoples R China
6.Chinese Acad Sci, Innovat Seed Design, Wuhan, Peoples R China

推荐引用方式
GB/T 7714Lyu, Ding,Yu, Yang,Wang, Quanchao,et al. Identification of Growth-Associated Genes by Genome-Wide Association Study and Their Potential Application in the Breeding of Pacific White Shrimp (Litopenaeus vannamei)[J]. FRONTIERS IN GENETICS,2021,12:9.
APALyu, Ding.,Yu, Yang.,Wang, Quanchao.,Luo, Zheng.,Zhang, Qian.,...&Li, Fuhua.(2021).Identification of Growth-Associated Genes by Genome-Wide Association Study and Their Potential Application in the Breeding of Pacific White Shrimp (Litopenaeus vannamei).FRONTIERS IN GENETICS,12,9.
MLALyu, Ding,et al."Identification of Growth-Associated Genes by Genome-Wide Association Study and Their Potential Application in the Breeding of Pacific White Shrimp (Litopenaeus vannamei)".FRONTIERS IN GENETICS 12(2021):9.


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