Integrative phenotypic and gene expression data identify myostatin as a muscle growth inhibitor in chinese shrimp Fenneropenaeus chinensis
Jie Kong; Yunjun Yan; Xia Lu; Sheng Luan; Xianhong Meng; Ping Dai; Baolong chen; Baoxiang cao; Guangfeng Qiang; Kun Luo
发表期刊Scientific Reports
2020
卷号10页码:5985
DOIhttps://doi.org/10.1038/s41598-020-61382-8
英文摘要Growth traits, largely determined by muscle growth, are the most critical economic traits in shrimp breeding. Myostatin (Mstn) is a conserved inhibitor of muscle growth in vertebrates, but until now solid evidence supporting a similar function of?Mstn?in invertebrates has been lacking. In the present study, we examined the?Mstn?expression along with growth trait data in a?Fenneropenaeus chinensis?population, to establish a potential correlation between?Mstn?and growth. The heritabilities of?FcMstn?expression, body weight at 190 days of culture, body weight and length at 230 days of culture, and average daily gain were estimated using 773 individuals and a thirteen-generation pedigree. The results showed?FcMstn?expression was negatively correlated with the growth traits, and the mean?FcMstn?expression in females was significantly lower than that of males, indicating?Mstn?negatively regulates muscle growth in shrimp, and its lower expression may underscore the faster growth of females. Low heritabilities were detected for?FcMstn?expression, suggesting that the expression of?Mstn?might be heritable in shrimp. These results provide strong support for a growth inhibitory function of?Mstn?in?F. chinensis, and suggest a potential method for selective breeding of this species without substantial experimental resources and labor force.
收录类别SCI
语种英语
引用统计
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/25253
专题个人在本单位外知识产出

通讯作者Xia Lu推荐引用方式
GB/T 7714Jie Kong,Yunjun Yan,Xia Lu,et al. Integrative phenotypic and gene expression data identify myostatin as a muscle growth inhibitor in chinese shrimp Fenneropenaeus chinensis[J]. Scientific Reports,2020,10:5985.
APAJie Kong.,Yunjun Yan.,Xia Lu.,Sheng Luan.,Xianhong Meng.,...&Kun Luo.(2020).Integrative phenotypic and gene expression data identify myostatin as a muscle growth inhibitor in chinese shrimp Fenneropenaeus chinensis.Scientific Reports,10,5985.
MLAJie Kong,et al."Integrative phenotypic and gene expression data identify myostatin as a muscle growth inhibitor in chinese shrimp Fenneropenaeus chinensis".Scientific Reports 10(2020):5985.


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