Meng, Xiangjing; Li, Fei
; Wang, Xiaoqing; Liu, Jialin; Ji, Chenglong; Wu, Huifeng发表期刊MARINE POLLUTION BULLETIN
ISSN0025-326X
2020-02
卷号151页码:110838
关键词ORGANOPHOSPHATE FLAME RETARDANTSIN-VITROPRISTINE GRAPHENEOXIDATIVE STRESSMARINE MUSSELCAGED MUSSELSOXIDETOXICITYNANOPARTICLESNANOMATERIALS
研究领域Environmental Sciences; Marine & Freshwater Biology
DOI10.1016/j.marpolbul.2019.110838
产权排序[Meng, Xiangjing; Li, Fei; Wang, Xiaoqing; Liu, Jialin; Ji, Chenglong; Wu, Huifeng] Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Shandong Key Lab Coastal Environm Proc,YICCAS, Yantai 264003, Peoples R China; [Ji, Chenglong; Wu, Huifeng] Qingdao Natl Lab Marine Sci & Technol, Lab Marine Fisheries Sci & Food Prod Proc, Qingdao 266237, Peoples R China; [Meng, Xiangjing; Wang, Xiaoqing] Univ Chinese Acad Sci, Beijing 100049, Peoples R China; [Li, Fei; Ji, Chenglong; Wu, Huifeng] Chinese Acad Sci, Ctr Ocean Megasci, Qingdao 266071, Peoples R China
通讯作者Li, Fei(fli@yic.ac.cn); Wu, Huifeng(hfwu@yic.ac.cn)
作者部门海岸带环境过程实验室
英文摘要Graphene nanoparticles are increasingly released into the aquatic environment with the growth of production. However, there are rare investigations focusing on the interaction of nanoparticles with other contaminants. Triphenyl phosphate (TPP) is a frequently detected organophosphate flame retardant in the environment. This study aimed to assess the joint effects of graphene and TPP on Mytilus gallaprovincialis hemocytes. Oxidative stress could be induced by graphene and TPP in mussel hemocytes, which could further cause apoptosis, DNA damage and decrease in the lysosomal membrane stability (LMS). Moreover, hemocytes could internalize graphene, thereby resulting in oxidative stress. The oxidative stress and DNA damage in hemocytes were increased in the graphene-exposed group, but significantly reduced after combined exposure of graphene and TPP. The upregulated genes, including NF-kappa B, Bcl-2 and Ras, were mainly associated with reduced apoptosis and DNA damage after co-exposure to graphene and TPP.
文章类型Article
资助机构National Natural Science Foundation of ChinaNational Natural Science Foundation of China [41530642, 21677173, 41976152]; Youth Innovation Promotion Association CAS [2017255]
收录类别SCI
语种英语
关键词[WOS]ORGANOPHOSPHATE FLAME RETARDANTS; IN-VITRO; PRISTINE GRAPHENE; OXIDATIVE STRESS; MARINE MUSSEL; CAGED MUSSELS; OXIDE; TOXICITY; NANOPARTICLES; NANOMATERIALS
研究领域[WOS]Environmental Sciences & Ecology; Marine & Freshwater Biology
WOS记录号WOS:000514758400057
引用统计被引频次：7[WOS][WOS记录][WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/25094
专题中科院海岸带环境过程与生态修复重点实验室_海岸带环境过程实验室
支撑部门
中科院海岸带环境过程与生态修复重点实验室
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Shandong Key Lab Coastal Environm Proc,YICCAS, Yantai 264003, Peoples R China;
2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Fisheries Sci & Food Prod Proc, Qingdao 266237, Peoples R China;
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China;
4.Chinese Acad Sci, Ctr Ocean Megasci, Qingdao 266071, Peoples R China
推荐引用方式
GB/T 7714Meng, Xiangjing,Li, Fei,Wang, Xiaoqing,et al. Toxicological effects of graphene on mussel Mytilus galloprovincialis hemocytes after individual and combined exposure with triphenyl phosphate[J]. MARINE POLLUTION BULLETIN,2020,151:110838.
APAMeng, Xiangjing,Li, Fei,Wang, Xiaoqing,Liu, Jialin,Ji, Chenglong,&Wu, Huifeng.(2020).Toxicological effects of graphene on mussel Mytilus galloprovincialis hemocytes after individual and combined exposure with triphenyl phosphate.MARINE POLLUTION BULLETIN,151,110838.
MLAMeng, Xiangjing,et al."Toxicological effects of graphene on mussel Mytilus galloprovincialis hemocytes after individual and combined exposure with triphenyl phosphate".MARINE POLLUTION BULLETIN 151(2020):110838.
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