Yu, Deliang; Wu, Huifeng
; Peng, Xiao; Ji, Chenglong; Zhang, Xiaoying; Song, Jun; Qu, Junle发表期刊COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
ISSN1532-0456
2020-04
卷号230页码:108697
关键词CUCUMBER APOSTICHOPUS-JAPONICUSOYSTER OSTREA-EDULISMETABOLOMIC ANALYSISOXIDATIVE STRESSDIGESTIVE GLANDLET-7EXPRESSIONMIRNASIDENTIFICATIONDROSOPHILA
研究领域Biochemistry & Molecular Biology; Endocrinology & Metabolism; Toxicology; Zoology
DOI10.1016/j.cbpc.2019.108697
产权排序[Yu, Deliang; Peng, Xiao; Song, Jun; Qu, Junle] Shenzhen Univ, Coll Phys & Optoelect Engn, Key Lab Optoelect Devices & Syst, Minist Educ & Guangdong Prov, Shenzhen 518060, Peoples R China; [Wu, Huifeng; Ji, Chenglong] Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Peoples R China; [Zhang, Xiaoying] Shenzhen Univ, Hlth Sci Ctr, AstraZeneca, Dept Physiol,Joint Inst Nephrol, Shenzhen 518060, Peoples R China
通讯作者Peng, Xiao(pengxiao_px@szu.edu.cn)
作者部门海岸带环境过程实验室
英文摘要MicroRNAs (miRNAs) are a class of noncoding RNA molecules containing 18-24 nucleotides, and those with conserved structures are able to regulate the expression of eukaryotic genes by inhibition or enhancement of mRNA translation. However, miRNAs of the blue mussel, Mytilus galloprovincialis have not been reported. M. galloprovincialis is a primary species distributed along coastal zones worldwide. To reveal the repertoire of miRNAs in M. galloprovincialis, we constructed small RNA libraries prepared from three different mussels, which were then sequenced by Solexa deep sequencing technology. A total of 32,836,817, 33,359,113 and 33,093,562 clean reads from the tissues of the three M. galloprovincialis were obtained. Based on sequence similarities and hairpin structure predictions, 137 M. galloprovincialis miRNAs (mg-miRNA) were identified. Among the mgmiRNAs, 104 were conserved across species, whereas 33 might be novel and specific for M. galloprovincialis. Some of the mg-miRNAs, such as let-7 and the miR-100 family are playing key roles in many metabolic pathways and are worthy of further study. By performing a whole genome-scale characterization of mg-miRNAs and proposing their potential functions, these results provide a foundation for understanding the biological processes of the blue mussel, M. galloprovincialis.
文章类型Article
资助机构National Key Research and Development Program of China [2018YFC0910602]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China [31771584, 41806142, 61525503, 61620106016, 61835009, 41976152]; Department of Education of Guangdong ProvinceNational Natural Science Foundation of Guangdong Province [2016KCXTD007]; Guangdong Natural Science Foundation Innovation Team [2014A030312008]; Shenzhen Basic Research Project [JCYJ20170818100153423, JCYJ20170412105003520]; Natural Science Foundation of SZU [2017000193]; Shandong Key Laboratory of Coastal Environmental Processes, YICCAS [2019SDHADKFJJ03]; China Postdoctoral Science FoundationChina Postdoctoral Science Foundation [2018M643151]
收录类别SCI
语种英语
关键词[WOS]CUCUMBER APOSTICHOPUS-JAPONICUS; OYSTER OSTREA-EDULIS; METABOLOMIC ANALYSIS; OXIDATIVE STRESS; DIGESTIVE GLAND; LET-7; EXPRESSION; MIRNAS; IDENTIFICATION; DROSOPHILA
研究领域[WOS]Biochemistry & Molecular Biology; Endocrinology & Metabolism; Toxicology; Zoology
WOS记录号WOS:000520945100007
引用统计被引频次：8[WOS][WOS记录][WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/25061
专题中科院海岸带环境过程与生态修复重点实验室_海岸带环境过程实验室
中科院海岸带环境过程与生态修复重点实验室
作者单位1.Shenzhen Univ, Coll Phys & Optoelect Engn, Key Lab Optoelect Devices & Syst, Minist Educ & Guangdong Prov, Shenzhen 518060, Peoples R China;
2.Chinese Acad Sci, Shandong Prov Key Lab Coastal Zone Environm Proc, Key Lab Coastal Zone Environm Proc & Ecol Remedia, Yantai Inst Coastal Zone Res YIC,YICCAS, Yantai 264003, Peoples R China;
3.Shenzhen Univ, Hlth Sci Ctr, AstraZeneca, Dept Physiol,Joint Inst Nephrol, Shenzhen 518060, Peoples R China
推荐引用方式
GB/T 7714Yu, Deliang,Wu, Huifeng,Peng, Xiao,et al. Profiling of microRNAs and mRNAs in marine mussel Mytilus galloprovincialis[J]. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY,2020,230:108697.
APAYu, Deliang.,Wu, Huifeng.,Peng, Xiao.,Ji, Chenglong.,Zhang, Xiaoying.,...&Qu, Junle.(2020).Profiling of microRNAs and mRNAs in marine mussel Mytilus galloprovincialis.COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY,230,108697.
MLAYu, Deliang,et al."Profiling of microRNAs and mRNAs in marine mussel Mytilus galloprovincialis".COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY 230(2020):108697.
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