Liu, SW; Ding, JW
; Qin, W发表期刊ANALYTICAL CHEMISTRY
ISSN0003-2700
2019-02-19
卷号91期号:4页码:3170-3176
关键词ION-SELECTIVE ELECTRODESSOLID-CONTACTLABEL-FREECOLORIMETRIC DETECTIONMEMBRANE ELECTRODESAPTAMERMOLECULESCYSTEINESYSTEMSSENSORS
研究领域Chemistry, Analytical
DOI10.1021/acs.analchem.8b05971
产权排序[Liu, Shuwen; Ding, Jiawang; Qin, Wei] Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Shandong, Peoples R China; [Liu, Shuwen; Ding, Jiawang; Qin, Wei] Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Shandong Prov Key Lab Coastal Environm Proc, Yantai 264003, Shandong, Peoples R China; [Ding, Jiawang; Qin, Wei] Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266200, Peoples R China; [Liu, Shuwen] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
作者部门海岸带环境过程实验室
英文摘要Conventional potentiometric ion sensors that rely on a specific ion carrier in a polymeric membrane can hardly achieve multianalyte detection. Inspired by the remarkable ability of built-in logic gate sensors for multianalyte detection, herein we report a potentiometric aptasensing platform based on a G-quadruplex/hemin DNAzyme and logic gate operations for determination of two analytes using a single membrane electrode. A bifunctional probe with two aptamer units and a signal reporter oligonucleotide with a DNAzyme sequence are assembled on the magnetic beads to form a DNA hybrid structure. The "OR" and "INHIBIT" logic functions can be performed by using the two aptamers and their targets as inputs, and using the chronopotentiometric response based on the G-quadruplex/hemin DNAzyme-H2O2-mediated oxidation of 3,3',5,5'-tetramethylbenzidine as output. Kanamycin and oxytetracycline, as commonly used antibiotics, have been employed as the models and successfully measured.
文章类型Article
资助机构National Natural Science Foundation of ChinaNational Natural Science Foundation of China [21575158, 21475148, 41876108]; National Key Research and Development Program of China [2016YFC1400700]; Instrument Developing Project of the Chinese Academy of Sciences [Y728021021]; Taishan Scholar Program of Shandong Province [TS20081159]
收录类别SCI
语种英语
关键词[WOS]ION-SELECTIVE ELECTRODES; SOLID-CONTACT; LABEL-FREE; COLORIMETRIC DETECTION; MEMBRANE ELECTRODES; APTAMER; MOLECULES; CYSTEINE; SYSTEMS; SENSORS
研究领域[WOS]Chemistry, Analytical
WOS记录号WOS:000459642400083
引用统计被引频次：24[WOS][WOS记录][WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/24998
专题中科院海岸带环境过程与生态修复重点实验室_海岸带环境过程实验室
中科院海岸带环境过程与生态修复重点实验室
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Shandong, Peoples R China;
2.Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, Shandong Prov Key Lab Coastal Environm Proc, Yantai 264003, Shandong, Peoples R China;
3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266200, Peoples R China;
4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714Liu, SW,Ding, JW,Qin, W. Dual-Analyte Chronopotentiometric Aptasensing Platform Based on a G-Quadruplex/Hemin DNAzyme and Logic Gate Operations[J]. ANALYTICAL CHEMISTRY,2019,91(4):3170-3176.
APALiu, SW,Ding, JW,&Qin, W.(2019).Dual-Analyte Chronopotentiometric Aptasensing Platform Based on a G-Quadruplex/Hemin DNAzyme and Logic Gate Operations.ANALYTICAL CHEMISTRY,91(4),3170-3176.
MLALiu, SW,et al."Dual-Analyte Chronopotentiometric Aptasensing Platform Based on a G-Quadruplex/Hemin DNAzyme and Logic Gate Operations".ANALYTICAL CHEMISTRY 91.4(2019):3170-3176.
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