Yang, Q; Li, JH
; Wang, XY; Xiong, H; Chen, LX发表期刊ANALYTICAL CHEMISTRY
ISSN0003-2700
2019-05-21
卷号91期号:10页码:6561-6568
关键词SENSITIVE DETECTIONQUANTUM DOTSCARBON DOTSPOLYMERSQDS
研究领域Chemistry, Analytical
DOI10.1021/acs.analchem.9b00082
产权排序[Yang, Qian; Li, Jinhua; Wang, Xiaoyan; Chen, Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China; [Yang, Qian; Xiong, Hua] Nanchang Univ, State Key Lab Food Sci & Technol, Nanchang 330047, Jiangxi, Peoples R China; [Wang, Xiaoyan] Binzhou Med Univ, Sch Pharm, Yantai 264003, Peoples R China; [Chen, Lingxin] Pilot Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 13266237, Shandong, Peoples R China; [Chen, Lingxin] Chinese Acad Sci, Ctr Ocean Mega Sci, 7 Nanhai Rd, Qingdao 266071, Shandong, Peoples R China
通讯作者Xiong, Hua(huaxiong100@126.com); Chen, Lingxin(lxchen@yic.ac.cn)
作者部门海岸带环境工程技术研究与发展中心
英文摘要A novel ternary-emission fluorescence sensor was proposed by post-imprinting mixing blue-/green-/red-emission bovine hemoglobin (BHb) imprinted polymers (b-MIPs, g-MIPs, and r-MIPs) at a proper ratio and realized the multiplexed and visual detection of BHb. The three MIPs were individually embedded with blue-emission 7-hydroxycoumarin, green-emission CdTe quantum dots (QDs), and red-emission CdTe/ZnS QDs. Upon interaction with BHb within 8 min, the fluorescence of CdTe and CdTe/ZnS QDs were simultaneously turned off, whereas the 7-hydroxycoumarin turned on the fluorescence intensity. Thereupon, the ratiometric fluorescence intensity of the ternary emission linearly varied within 0.025-3 mu M BHb, accompanying the profuse fluorescence color evolution from yellowish green to yellow to salmon to plum to purple to finally blue. In comparison with the dual- or single-emission sensor, the ternary-emission fluorescence MIPs sensor provided a wider color variation covering the green-red-blue window for accurate naked-eye determination of BHb, as well as a lower detection limit down to 7.8 nM and a higher imprinting factor of 15.2. Moreover, the satisfactory recoveries of 99.25-111.7% in determining the spiked BHb in bovine urine samples, as well as the optical stability and post-imprinting construction convenience, indicated that the developed tricolor-emission fluorescence MIPs sensor provided an ideal alternative for rapid, sensitive, and visual determination of proteins in complicated samples.
文章类型Article
资助机构National Natural Science Foundation of ChinaNational Natural Science Foundation of China [21876199, 21575159, 21804010, 21667018, 31860470, 31660482, 41776110]
收录类别SCI
语种英语
关键词[WOS]SENSITIVE DETECTION; QUANTUM DOTS; CARBON DOTS; POLYMERS; QDS
研究领域[WOS]Chemistry, Analytical
WOS记录号WOS:000469304300023
引用统计被引频次：49[WOS][WOS记录][WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/24938
专题中科院海岸带环境过程与生态修复重点实验室_海岸带环境工程技术研究与发展中心
中科院海岸带环境过程与生态修复重点实验室
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China;
2.Nanchang Univ, State Key Lab Food Sci & Technol, Nanchang 330047, Jiangxi, Peoples R China;
3.Binzhou Med Univ, Sch Pharm, Yantai 264003, Peoples R China;
4.Pilot Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 13266237, Shandong, Peoples R China;
5.Chinese Acad Sci, Ctr Ocean Mega Sci, 7 Nanhai Rd, Qingdao 266071, Shandong, Peoples R China
推荐引用方式
GB/T 7714Yang, Q,Li, JH,Wang, XY,et al. Ternary Emission of a Blue-, Green-, and Red-Based Molecular Imprinting Fluorescence Sensor for the Multiplexed and Visual Detection of Bovine Hemoglobin[J]. ANALYTICAL CHEMISTRY,2019,91(10):6561-6568.
APAYang, Q,Li, JH,Wang, XY,Xiong, H,&Chen, LX.(2019).Ternary Emission of a Blue-, Green-, and Red-Based Molecular Imprinting Fluorescence Sensor for the Multiplexed and Visual Detection of Bovine Hemoglobin.ANALYTICAL CHEMISTRY,91(10),6561-6568.
MLAYang, Q,et al."Ternary Emission of a Blue-, Green-, and Red-Based Molecular Imprinting Fluorescence Sensor for the Multiplexed and Visual Detection of Bovine Hemoglobin".ANALYTICAL CHEMISTRY 91.10(2019):6561-6568.
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