Jiang, XJ; Wang, P; Liang, RN
; Qin, W发表期刊ANALYTICAL CHEMISTRY
ISSN0003-2700
2019-05-21
卷号91期号:10页码:6424-6429
关键词SELECTIVE ELECTRODESBLOOD COMPATIBILITYPHOSPHORYLCHOLINESURFACES
研究领域Chemistry, Analytical
DOI10.1021/acs.analchem.9b00039
产权排序[Jiang, Xiaojing; Liang, Rongning; Qin, Wei] Chinese Acad Sci, Yantai Inst Coastal Zone Res, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Shandong, Peoples R China; [Jiang, Xiaojing; Liang, Rongning; Qin, Wei] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Shandong Key Lab Coastal Environm Proc, Yantai 264003, Shandong, Peoples R China; [Liang, Rongning; Qin, Wei] Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266200, Shandong, Peoples R China; [Jiang, Xiaojing] Univ Chinese Acad Sci, Beijing 100049, Peoples R China; [Wang, Peng] Shandong B&E Biotechnol Co Ltd, Yantai, Peoples R China
通讯作者Liang, Rongning(rnliang@yic.ac.cn); Qin, Wei(wqin@yic.ac.cn)
作者部门海岸带环境过程实验室
英文摘要Polymeric membrane potentiometric ion sensors have been widely used in clinical diagnosis for the detection of electrolyte ions and account for billions of measurements every year throughout the world. However, in many cases of practical relevance, biofouling, which might lead to sensor failure, usually occurs due to the lack of biocompatibility of these sensors. Herein, we describe a simple and robust approach for improving the biocompatibility of the polymeric ion-selective membranes. A marine mussel-inspired polydopamine polymer is used as a hydrophilic coating on the surface of conventional potentiometric ion sensors. Such a coating can be easily formed by self-polymerization of dopamine and robustly deposited on the sensor surface mimicking the adhesion mechanism of mussels. The classical poly(vinyl chloride) membrane-based calcium ion-selective electrode (ISE) is chosen as a model. Compared to the unmodified Ca2+ ISE, the polydopamine modified electrode shows a significantly reduced blood platelet adsorption while retaining original potentiometric ion response properties, which clearly indicates a high antifouling capability induced by the hydrophilic polydopamine coating. We believe that the proposed approach can provide an appealing way to improve the biocompatibility in the development of polymeric membrane electrochemical and optical sensors.
文章类型Article
资助机构National Natural Science Foundation of ChinaNational Natural Science Foundation of China [21874151, 21677172, 41576106]; National Key Research and Development Program of China [2016YFC1400700]; Youth Innovation Promotion Association of CAS [2014190]; Taishan Scholar Program of Shandong Province [tspd20181215]
收录类别SCI
语种英语
关键词[WOS]SELECTIVE ELECTRODES; BLOOD COMPATIBILITY; PHOSPHORYLCHOLINE; SURFACES
研究领域[WOS]Chemistry, Analytical
WOS记录号WOS:000469304300006
引用统计被引频次：18[WOS][WOS记录][WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/24937
专题中科院海岸带环境过程与生态修复重点实验室_海岸带环境过程实验室
中科院海岸带环境过程与生态修复重点实验室
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Shandong, Peoples R China;
2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Shandong Key Lab Coastal Environm Proc, Yantai 264003, Shandong, Peoples R China;
3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266200, Shandong, Peoples R China;
4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China;
5.Shandong B&E Biotechnol Co Ltd, Yantai, Peoples R China
推荐引用方式
GB/T 7714Jiang, XJ,Wang, P,Liang, RN,et al. Improving the Biocompatibility of Polymeric Membrane Potentiometric Ion Sensors by Using a Mussel-Inspired Polydopamine Coating[J]. ANALYTICAL CHEMISTRY,2019,91(10):6424-6429.
APAJiang, XJ,Wang, P,Liang, RN,&Qin, W.(2019).Improving the Biocompatibility of Polymeric Membrane Potentiometric Ion Sensors by Using a Mussel-Inspired Polydopamine Coating.ANALYTICAL CHEMISTRY,91(10),6424-6429.
MLAJiang, XJ,et al."Improving the Biocompatibility of Polymeric Membrane Potentiometric Ion Sensors by Using a Mussel-Inspired Polydopamine Coating".ANALYTICAL CHEMISTRY 91.10(2019):6424-6429.
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