Zhang, JJ; Mi, YQ; Sun, XQ; Chen, Y; Miao, Q; Tan, WQ
; Li, Q; Dong, F; Guo, ZY发表期刊STARCH-STARKE
ISSN0038-9056
2020
卷号72期号:5-6页码:1900205
关键词antifungal activityantioxidant activitychitosan derivativesurea groups
研究领域Food Science & Technology
DOI10.1002/star.201900205
产权排序[Zhang, Jingjing; Mi, Yingqi; Sun, Xueqi; Chen, Yuan; Miao, Qin; Tan, Wenqiang; Li, Qing; Dong, Fang; Guo, Zhanyong] Chinese Acad Sci, Key Lab Coastal Biol & Bioresource Utilizat, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; [Zhang, Jingjing; Mi, Yingqi; Sun, Xueqi; Chen, Yuan; Miao, Qin; Tan, Wenqiang; Li, Qing; Dong, Fang; Guo, Zhanyong] Chinese Acad Sci, Ctr Ocean Mega Sci, 7 Nanhai Rd, Qingdao 266071, Peoples R China; [Zhang, Jingjing; Mi, Yingqi; Sun, Xueqi; Chen, Yuan; Guo, Zhanyong] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
通讯作者Guo, Zhanyong(zhanyongguo@hotmail.com)
作者部门海岸带生物学与生物资源保护实验室
英文摘要Eight novel chitosan derivatives bearing urea groups are designed and synthesized. Fourier transform infrared spectroscopy, H-1 nuclear magnetic resonance spectrometer, and elemental analysis are performed to confirm the structural characteristics of chitosan derivatives. The antioxidant activities, including superoxide radicals' scavenging activity, 1,1-diphenyl-2-picrylhydrazyl radicals' scavenging activity, and hydroxyl radical' scavenging activity, of the derivatives are explored within different concentrations in the reaction system. In vitro fungicidal activity of these compounds is further tested against Fusarium oxysporum f. sp. niveum, Phomopsis asparagus, F. oxysporum f. sp. cucumebrium Owen, and Botrytis cinerea, respectively, particularly compounds exhibit significant control effect at 1.0 mg mL(-1). The experimental results indicate that the products bearing urea groups show enhanced antifungal property and antioxidant activity compared with pristine chitosan. Meanwhile, their bioactivities follow some regularity on the whole, that is, they are related to the electron-withdrawing property of the different substituted groups of urea. Derivatives with stronger electron-withdrawing property will have higher biological activities. L929 cells are used to carry out cytotoxicity test of chitosan and chitosan derivatives by Cell Counting Kit-8 assay. The results indicate that some of the samples show low cytotoxicity. This research will be helpful to broaden the application of chitosan in materials.
文章类型Article
资助机构Natural Science Foundation of Shandong Province Science and Technology Development Plan [2019GHY112010]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China [41576156]; Natural Science Foundation of Shandong Province of ChinaNatural Science Foundation of Shandong Province [ZR2017BD015, ZR2019BD064]
收录类别SCI
语种英语
关键词[WOS]IN-VITRO; ENHANCED ANTIOXIDANT; ANTIBACTERIAL; COMPLEXES
研究领域[WOS]Food Science & Technology
WOS记录号WOS:000505836700001
引用统计被引频次：1[WOS][WOS记录][WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/24770
专题海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心
海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
作者单位1.Chinese Acad Sci, Key Lab Coastal Biol & Bioresource Utilizat, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China;
2.Chinese Acad Sci, Ctr Ocean Mega Sci, 7 Nanhai Rd, Qingdao 266071, Peoples R China;
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714Zhang, JJ,Mi, YQ,Sun, XQ,et al. Improved Antioxidant and Antifungal Activity of Chitosan Derivatives Bearing Urea Groups[J]. STARCH-STARKE,2020,72(5-6):1900205.
APAZhang, JJ.,Mi, YQ.,Sun, XQ.,Chen, Y.,Miao, Q.,...&Guo, ZY.(2020).Improved Antioxidant and Antifungal Activity of Chitosan Derivatives Bearing Urea Groups.STARCH-STARKE,72(5-6),1900205.
MLAZhang, JJ,et al."Improved Antioxidant and Antifungal Activity of Chitosan Derivatives Bearing Urea Groups".STARCH-STARKE 72.5-6(2020):1900205.
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