Lin, D; Li, BW
; Qi, J; Ji, XF; Yang, SX; Wang, WH; Chen, LX发表期刊SENSORS AND ACTUATORS B-CHEMICAL
2020-01-15
卷号303页码:127213
关键词Paper microfluidicsmuPADPolyurethane acrylateUltraviolet light curingBacterial detection
研究领域Chemistry, Analytical; Electrochemistry; Instruments & Instrumentation
DOI10.1016/j.snb.2019.127213
产权排序[Lin, Dong; Li, Bowei; Qi, Ji; Yang, Shixuan; Wang, Wenhai; Chen, Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China; [Lin, Dong; Ji, Xiaofei; Chen, Lingxin] Binzhou Med Univ, Sch Pharm, Yantai 264003, Peoples R China; [Chen, Lingxin] Pilot Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266237, Shandong, Peoples R China; [Li, Bowei] Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266071, Shandong, Peoples R China
通讯作者Li, Bowei(bwli@yic.ac.cn); Chen, Lingxin(lxchen@yic.ac.cn)
作者部门海岸带环境工程技术研究与发展中心
英文摘要This study presents a simple, inexpensive and environment-friendly fabrication strategy for microfluidic paper-based analytical devices which can resist the penetration of surfactant solutions and organic solvents, by using water-based polyurethane acrylate via UV light curing. The filter paper's barrier created using cured PUA could withstand surfactant solutions (10 wt%, CTAB, SDS and Triton X-100) and organic solvents (methanol, isopropanol, DMF, DMSO, etc). This is very useful for analyzing complicated biological samples on the microfluidic paper-based analytical devices. In addition, the expense of water-based polyurethane acrylate is very cheap (about $8/500 g) and PUA developer is water that is environmental-friendly. To further verify its advantage, we successfully demonstrated the proposed microfluidic devices for detection of E. coli targets in tap water and seawater via colorimetric analysis in a fast and convenient manner. Our results revealed that the linear response to E. coli BL21 was in the range of 10(4)similar to 10(9) cfu/mL. The proposed method can effectively avoid the damage for the hydrophobic barriers from the solution even some aggressive liquids, and shows great potential in on-site analysis, environmental monitoring, and food safety.
文章类型Article
资助机构National Key Research and Development Program of China [2016YFC1400702]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China [41776110, 21976209, 21876199]; Shandong Provincial Medicine and Health Technology Development Plan [2017WSB290215]; Science and Technology Development Plan of Yantai [2017ZH089]; Department of Science and Technology of Shandong Province of China [GG201709290055, 2017ZH093]; Taishan Scholar Project Special Funding
收录类别SCI
语种英语
关键词[WOS]FLUORESCENCE DETECTION; INK-JET; WAX; BARRIERS; CHIP; ION
研究领域[WOS]Chemistry, Analytical; Electrochemistry; Instruments & Instrumentation
WOS记录号WOS:000500370900005
引用统计被引频次：37[WOS][WOS记录][WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/24769
专题中科院海岸带环境过程与生态修复重点实验室_海岸带环境工程技术研究与发展中心
中科院海岸带环境过程与生态修复重点实验室
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China;
2.Binzhou Med Univ, Sch Pharm, Yantai 264003, Peoples R China;
3.Pilot Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266237, Shandong, Peoples R China;
4.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266071, Shandong, Peoples R China
推荐引用方式
GB/T 7714Lin, D,Li, BW,Qi, J,et al. Low cost fabrication of microfluidic paper-based analytical devices with water-based polyurethane acrylate and their application for bacterial detection[J]. SENSORS AND ACTUATORS B-CHEMICAL,2020,303:127213.
APALin, D.,Li, BW.,Qi, J.,Ji, XF.,Yang, SX.,...&Chen, LX.(2020).Low cost fabrication of microfluidic paper-based analytical devices with water-based polyurethane acrylate and their application for bacterial detection.SENSORS AND ACTUATORS B-CHEMICAL,303,127213.
MLALin, D,et al."Low cost fabrication of microfluidic paper-based analytical devices with water-based polyurethane acrylate and their application for bacterial detection".SENSORS AND ACTUATORS B-CHEMICAL 303(2020):127213.
PDF全文下载地址:
点我下载PDF
