Mei, RC; Wang, YQ
; Yu, Q; Yin, YC; Zhao, RF; Chen, LX发表期刊ACS APPLIED MATERIALS & INTERFACES
ISSN1944-8244
2020-01-15
卷号12期号:2页码:2059-2066
关键词SERSgold nanorodsilver nanoparticlebimetallicinternal standard
研究领域Nanoscience & Nanotechnology; Materials Science, Multidisciplinary
DOI10.1021/acsami.9b18292
产权排序[Mei, Rongchao; Wang, Yunqing; Yu, Qian; Zhao, Rongfang; Chen, Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China; [Yin, Yingchao] Yantai Univ, Collaborat Innovat Ctr Adv Drug Delivery Syst & B, Sch Pharm, Key Lab Mol Pharmacol & Drug Evaluat,Minist Educ, Yantai 264005, Peoples R China; [Chen, Lingxin] Qufu Normal Univ, Coll Chem & Chem Engn, Qufu 273165, Shandong, Peoples R China; [Chen, Lingxin] Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266071, Peoples R China
通讯作者Wang, Yunqing(yqwang@yic.ac.cn); Chen, Lingxin(lxchen@yic.ac.cn)
作者部门海岸带环境工程技术研究与发展中心
英文摘要Bimetallic gold core-silver shell (Au@Ag) surface-enhanced Raman scattering (SERS) tags draw broad interest in the fields of biological and environmental analysis. In reported tags, silver coating tended to smooth the surface and merge the original hotspot of Au cores, which was disadvantageous to signal enhancement from the aspect of surface topography. Herein, we developed gold nanorod (AuNR)-bridged AupAg SERS tags with uniform three-dimensional (3D) topography for the first time. This unique structure was achieved by selecting waxberry-like Au nanoparticles (NPs) as cores, which were capped by vertically oriented AuNR arrays. Upon selective surface blocking with thiol-ligands, Ag NPs were controlled to anisotropically grow on the tips of the AuNRs, producing high-density homo- (Ag-Ag) and hetero- (Au-Ag) hotspots in a single NP. The 3D hotspots rendered this NP extraordinary SERS enhancement ability (an analytical enhancement factor of 3.4 x 10(6)) 30 times higher than the counterpart with a smooth surface, realizing signal detection from a single NP. More importantly, multiplexing signals ("blank" or multiplex "internal standard") can be achieved by simply changing thiol-ligands, as exemplified in the synthesis of NPs with 8 signatures. Furthermore, the multifunctionality has been demonstrated in living cell/in vivo imaging, photothermal therapy, and SERS substrates for ratiometric quantitative analysis, relying on the inherent internal standard signal. The prepared Au@Ag NPs have great potential as standard tools in many SERS-related fields.
文章类型Article
资助机构National Natural Science Foundation of ChinaNational Natural Science Foundation of China [81573393, 21976209]; Science and Technology Development Plan of Shandong Province of China [2019GSF108047]; Youth Innovation Promotion Association CAS [2017256]; Instrument Developing Project of the Chinese Academy of Sciences [YZ201662]; Taishan Scholar Project Special Funding [ts20190962]
收录类别SCI
语种英语
关键词[WOS]ENHANCED RAMAN-SCATTERING; SURFACE; SHELL; NANOPARTICLES; NANOSTRUCTURES; NANOSTARS; NANOGAP; POLYMER
研究领域[WOS]Nanoscience & Nanotechnology; Materials Science, Multidisciplinary
WOS记录号WOS:000508464500009
引用统计被引频次：24[WOS][WOS记录][WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/24768
专题中科院海岸带环境过程与生态修复重点实验室_海岸带环境工程技术研究与发展中心
中科院海岸带环境过程与生态修复重点实验室
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China;
2.Yantai Univ, Collaborat Innovat Ctr Adv Drug Delivery Syst & B, Sch Pharm, Key Lab Mol Pharmacol & Drug Evaluat,Minist Educ, Yantai 264005, Peoples R China;
3.Qufu Normal Univ, Coll Chem & Chem Engn, Qufu 273165, Shandong, Peoples R China;
4.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266071, Peoples R China
推荐引用方式
GB/T 7714Mei, RC,Wang, YQ,Yu, Q,et al. Gold Nanorod Array-Bridged Internal-Standard SERS Tags: From Ultrasensitivity to Multifunctionality[J]. ACS APPLIED MATERIALS & INTERFACES,2020,12(2):2059-2066.
APAMei, RC,Wang, YQ,Yu, Q,Yin, YC,Zhao, RF,&Chen, LX.(2020).Gold Nanorod Array-Bridged Internal-Standard SERS Tags: From Ultrasensitivity to Multifunctionality.ACS APPLIED MATERIALS & INTERFACES,12(2),2059-2066.
MLAMei, RC,et al."Gold Nanorod Array-Bridged Internal-Standard SERS Tags: From Ultrasensitivity to Multifunctionality".ACS APPLIED MATERIALS & INTERFACES 12.2(2020):2059-2066.
PDF全文下载地址:
点我下载PDF
