Cao, Ruiwen; Wang, Dan; Wei, Qianyu; Wang, Qing
; Yang, Dinglong; Liu, Hui; Dong, Zhijun; Zhang, Xiaoli; Zhang, Qianqian; Zhao, Jianmin发表期刊FRONTIERS IN PHYSIOLOGY
ISSN1664-042X
2018-08-21
卷号9页码:1173
关键词saxitoxinCrassostrea gigasChlamys farrerioxidative stressimmunotoxicity
研究领域Physiology
DOI10.3389/fphys.2018.01173
产权排序[Cao, Ruiwen; Wang, Dan; Wei, Qianyu; Wang, Qing; Yang, Dinglong; Liu, Hui; Dong, Zhijun; Zhang, Xiaoli; Zhang, Qianqian; Zhao, Jianmin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Muping Coastal Environm Res Stn, Yantai, Peoples R China; [Cao, Ruiwen; Wang, Qing; Yang, Dinglong; Liu, Hui; Dong, Zhijun; Zhang, Xiaoli; Zhang, Qianqian; Zhao, Jianmin] Chinese Acad Sci Yantai, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Biol Resources Utilizat, Yantai, Peoples R China; [Cao, Ruiwen] Univ Chinese Acad Sci, Beijing, Peoples R China
作者部门中国科学院牟平海岸带环境综合试验站
英文摘要Harmful algae blooms have expanded greatly in recent decades, and their secreted toxins pose a severe threat to human health and marine ecosystems. Saxitoxin (STX) is a main paralytic shellfish poison naturally produced by marine microalgae of the genus Alexandrium. Despite numerous studies have assessed the impacts of STX on marine bivalves, comparative in vivo study on the toxicity of STX on bivalves with distinct accumulation ability (such as oysters and scallops) has been seldom investigated. The aim of this study was to identify whether distinct sensitivity exists between oysters, Crassostrea gigas, and scallops, Chlamys farreri under the same amount of STX exposure using multiple biomarker responses. The responses of different biochemical markers including oxidative stress markers (catalase, superoxide dismutase, glutathione S-transferase, and lipid peroxidation) and immunotoxicity biomarkers (hemocyte phagocytosis rate, reactive oxidative species production, and DNA damages) were evaluated in bivalves after 12, 48, and 96 h of exposure to STX. The integrated biomarker responses value combined with two-way ANOVA analysis suggested that STX posed slightly severer stress on scallops than oysters for the extended period of time. This study provided preliminary results on the usefulness of a multi-biomarker approach to assess the toxicity associated with STX exposure in marine bivalves.
文章类型Article
资助机构Strategic Priority Research Program of the Chinese Academy of Sciences [XDA11020305]; Key Research Program of the Chinese Academy of Sciences [KZZDEW-14]; Informatization Engineering of Scientific Research [XXH13506-305]; Instrument Developing Project of the Chinese Academy of Sciences [YJKYYQ20170071]; Youth Innovation Promotion Association, CAS [2016196]
收录类别SCI
语种英语
关键词[WOS]MUSSEL MYTILUS-GALLOPROVINCIALIS; PARALYTIC SHELLFISH TOXIN; HARMFUL ALGAL BLOOMS; OXIDATIVE STRESS; RUDITAPES-PHILIPPINARUM; ALEXANDRIUM-MINUTUM; TRANSCRIPTIONAL RESPONSES; BIOCHEMICAL RESPONSES; GYMNODINIUM-CATENATUM; ANTIOXIDANT RESPONSES
研究领域[WOS]Physiology
WOS记录号WOS:000442246500001
引用统计被引频次：12[WOS][WOS记录][WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/24514
专题支撑部门_中国科学院牟平海岸带环境综合试验站
海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
中科院海岸带环境过程与生态修复重点实验室_海岸带环境过程实验室
中科院海岸带环境过程与生态修复重点实验室
海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Muping Coastal Environm Res Stn, Yantai, Peoples R China;
2.Chinese Acad Sci Yantai, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Biol Resources Utilizat, Yantai, Peoples R China;
3.Univ Chinese Acad Sci, Beijing, Peoples R China
推荐引用方式
GB/T 7714Cao, Ruiwen,Wang, Dan,Wei, Qianyu,et al. Integrative Biomarker Assessment of the Influence of Saxitoxin on Marine Bivalves: A Comparative Study of the Two Bivalve Species Oysters, Crassostrea gigas, and Scallops, Chlamys farreri[J]. FRONTIERS IN PHYSIOLOGY,2018,9:1173.
APACao, Ruiwen.,Wang, Dan.,Wei, Qianyu.,Wang, Qing.,Yang, Dinglong.,...&Zhao, Jianmin.(2018).Integrative Biomarker Assessment of the Influence of Saxitoxin on Marine Bivalves: A Comparative Study of the Two Bivalve Species Oysters, Crassostrea gigas, and Scallops, Chlamys farreri.FRONTIERS IN PHYSIOLOGY,9,1173.
MLACao, Ruiwen,et al."Integrative Biomarker Assessment of the Influence of Saxitoxin on Marine Bivalves: A Comparative Study of the Two Bivalve Species Oysters, Crassostrea gigas, and Scallops, Chlamys farreri".FRONTIERS IN PHYSIOLOGY 9(2018):1173.
PDF全文下载地址:
点我下载PDF
