Luan, Fang; Wei, Lijie; Zhang, Jingjing; Tan, Wenqiang
; Chen, Yuan; Dong, Fang; Li, Qing; Guo, Zhanyong发表期刊MOLECULES
ISSN1420-3049
2018-03
卷号23期号:3页码:516
关键词cationic chitosan derivativesquaternized chitosandouble quaternized chitosanantioxidant ability
研究领域Biochemistry & Molecular Biology; Chemistry
DOI10.3390/molecules23030516
产权排序[Luan, Fang; Wei, Lijie; Zhang, Jingjing; Tan, Wenqiang; Chen, Yuan; Dong, Fang; Li, Qing; Guo, Zhanyong] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Shangdong, Peoples R China; [Luan, Fang; Wei, Lijie; Zhang, Jingjing; Tan, Wenqiang; Chen, Yuan; Guo, Zhanyong] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
作者部门海岸带生物学与生物资源保护实验室
英文摘要Chitosan (CS) is an abundant and renewable polysaccharide that is reported to exhibit a great variety of beneficial properties. However, the poor solubility of chitosan in water limits its applications. In this paper, we successfully synthesized single N-quaternized (QCS) and double N-diquaternized (DQCS) chitosan derivatives, and the resulting quaternized materials were water-soluble. The degree of quaternization (DQ) of QCS and DQCS was 0.8 and 1.3, respectively. These derivatives were characterized by FTIR, H-1 NMR, C-13 NMR, TGA, and SEM. Moreover, the antioxidant activity of the chitosan was evaluated by free radical scavenging ability (against DPPH-radical, hydroxyl-radical, and superoxide-radical) and ferric reducing power. Our results suggested that the antioxidant abilities were in the order of DQCS > QCS > CS, which was consistent with the number of quaternized groups. These data demonstrate that the number of quaternized groups of chitosan derivatives contributes to their antioxidant activity. Therefore, DQCS, with a higher number of quaternized groups and higher positive charge density, is endowed with high antioxidant activity, and can be used as a candidate material in food and pharmaceutical industries.
文章类型Article
资助机构Natural Science Foundation of China [41576156]; Shandong Province Science and Technology Development Plan [2015GSF121045]; Yantai Science and Technology Development Plan [2015ZH078]; Technology Research Funds Projects of Ocean [2015418022-3]
收录类别SCI
语种英语
关键词[WOS]ANTIBACTERIAL ACTIVITY; CHEMICAL-MODIFICATIONS; SCAVENGING ACTIVITY; TRIMETHYL CHITOSAN; AMMONIUM CHITOSAN; CHITIN; EXTRACTION; HYDROGELS; CHLORIDE
研究领域[WOS]Biochemistry & Molecular Biology; Chemistry, Multidisciplinary
WOS记录号WOS:000428514100007
引用统计被引频次：24[WOS][WOS记录][WOS相关记录]
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/24496
专题海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
中科院海岸带环境过程与生态修复重点实验室_污染过程与控制实验室
海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Shangdong, Peoples R China;
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714Luan, Fang,Wei, Lijie,Zhang, Jingjing,et al. Preparation and Characterization of Quaternized Chitosan Derivatives and Assessment of Their Antioxidant Activity[J]. MOLECULES,2018,23(3):516.
APALuan, Fang.,Wei, Lijie.,Zhang, Jingjing.,Tan, Wenqiang.,Chen, Yuan.,...&Guo, Zhanyong.(2018).Preparation and Characterization of Quaternized Chitosan Derivatives and Assessment of Their Antioxidant Activity.MOLECULES,23(3),516.
MLALuan, Fang,et al."Preparation and Characterization of Quaternized Chitosan Derivatives and Assessment of Their Antioxidant Activity".MOLECULES 23.3(2018):516.
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