Li, Qing
; Feng, Yan; Gu, Guodong; Guo, Zhanyong发表期刊STARCH-STARKE
ISSN0038-9056
2018-05
卷号70期号:5-6页码:1700293
关键词amino lactoseantioxidant activitychemical modifications
研究领域Food Science & Technology
DOI10.1002/star.201700293
产权排序[Li, Qing; Feng, Yan; Guo, Zhanyong] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China; [Feng, Yan; Guo, Zhanyong] Univ Chinese Acad Sci, Beijing 100049, Peoples R China; [Gu, Guodong] Alliance Pharma Inc, 17 Lee Blvd Malvern, Malvern, PA 19355 USA
作者部门海岸带生物资源高效利用研究与发展中心
英文摘要In order to improve the bioactivity of lactose, a novel lactose derivative is designed and synthesized by introducing an amino group to the C-6 of lactose. The in vitro antioxidant activities of synthesized lactose derivatives are assessed. It shows better scavenging activity against hydrogen peroxide (IC50<0.1mgmL(-1)), hydroxyl radicals (IC50 0.55mgmL(-1)), and DPPH radicals (IC50 0.37mgmL(-1)) than lactose. Based on this data, it is reasonable to propose that the introduction of amino group through chemical modification is significant to enhance the free antioxidant activity of lactose. This derivatization strategy might provide an effective tool to broaden utilization of lactose.
文章类型Article
资助机构Yantai Science and Technology Development Plan [2015ZH078]; Public Science and Technology Research Funds Projects of Ocean [201505022-3]; Natural Science Foundation of Shandong Province of China [ZR2017BD015]; National Natural Science Foundation of China [41576156]
收录类别SCI
语种英语
关键词[WOS]ANTIFUNGAL ACTIVITY; CHITOSAN DERIVATIVES; INULIN DERIVATIVES; DRUG-RELEASE; STARCH; FILMS; POLYSACCHARIDE; AMYLASE; DESIGN; IMPACT
研究领域[WOS]Food Science & Technology
WOS记录号WOS:000431735200022
引用统计
文献类型期刊论文
条目标识符http://ir.yic.ac.cnhttp://ir.yic.ac.cn/handle/133337/24477
专题海岸带生物学与生物资源利用重点实验室_海岸带生物资源高效利用研究与发展中心
海岸带生物学与生物资源利用重点实验室_海岸带生物学与生物资源保护实验室
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China;
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China;
3.Alliance Pharma Inc, 17 Lee Blvd Malvern, Malvern, PA 19355 USA
推荐引用方式
GB/T 7714Li, Qing,Feng, Yan,Gu, Guodong,et al. Synthesis of Novel Amino Lactose and Evaluation of Its Antioxidant Property[J]. STARCH-STARKE,2018,70(5-6):1700293.
APALi, Qing,Feng, Yan,Gu, Guodong,&Guo, Zhanyong.(2018).Synthesis of Novel Amino Lactose and Evaluation of Its Antioxidant Property.STARCH-STARKE,70(5-6),1700293.
MLALi, Qing,et al."Synthesis of Novel Amino Lactose and Evaluation of Its Antioxidant Property".STARCH-STARKE 70.5-6(2018):1700293.
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