潍坊医学院生命科学与技术学院导师教师师资介绍简介-韩阳阳

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生命科学与技术学院硕士研究生导师简介

专	业：	遗传学
姓	名：	韩阳阳
职	称：	副教授
研究领域：		肿瘤分子生物学及生物力学
邮	箱：	hanyy2009@163.com
电	话：	**015
主要社会兼职 1. 中国生物医学工程学会高级会员； 2. 中国生物化学与分子生物学学会会员；代表性专利及论文 1. FOXL2启动子基因的重组与构建的模型及应用，国家发明专利，已授权， 2018.01.18，ZL5081.7，第一发明人； 2. 上皮性卵巢癌的诊治靶标基因及其应用，国家发明专利，实审中，2019.10.21，，第一发明人。 3. Han Yangyang** #, Wu Jun#, Yang Weiwei#, Wang Di, Zhang Tianliang, Cheng Min. New STAT3-FOXL2 pathway and its function in cancer cells, BMC Molecular and Cell Biology, 2019, 20(1): 17 （中科院二区） 4. *Han Y.Y.,** Wang T.X., Sun S.D., Zhai Z.H., Tang S.J.. Cloning of the promoter region of a human gene, FOXL2, and its regulation by STAT3. Molecular Medicine Reports, 2017, 16(3): 2856-2862 5. Han Y.Y.* #, Chen Y.H.#, Yin S.H., Zhang M., Wang W.. Overexpression of TaEXPB23, a wheat expansin gene, improves oxidative stress tolerance in transgenic tobacco plants. Journal of Plant Physiology, 2015, 173: 62-71 Q1（中科院二区） 6. Han Y.Y.#, Zhou S.#, Chen Y.H., Kong X.Z., Xu Y., Wang W.. The involvement of expansins in responses to phosphorus availability in wheat, and its potentials in improving phosphorus efﬁciency of plants. Plant Physiology and Biochemistry, 2014, 78: 53-62 7. Han Y.Y., Li A.X., Li F., Zhao M.R., Wang W.*. Characterization of a wheat

(Triticum aestivum L.) expansin gene, TaEXPB23, involved in the abiotic stressresponse and phytohormone regulation. PlantPhysiology and Biochemistry, 2012,54: 49-58

8.Xinli Ouyang #, Yangyang Han#, Yongfang Xie#, Yide Wu,Shaojia Guo, Min Cheng, Guohui Wang. The collagen metabolism aﬀects the scleral mechanical properties in the diﬀerent processes of scleral remodeling, Biomedicine & Pharmacotherapy, 2019, 118

9.Li F. #, Han Y.Y. # (co-first author), Feng Y.N., Xing S.C., Zhao M.R.,Chen Y.H., Wang W.*. The ectopic expression of wheat expansins in tobaccodriven by the RD29 promoter conferswater stress tolerance and improved phenotype. Journal of Biotechnology,2013, 163: 281-291 （中科院二区）

10.Wang W.Q.#, Tian F.X. #, Hao Q.Q. #, Han Y.Y. # (co-first author), Li Q.X., Wang X., Wang W.L., Wang Y., Wang W*.. Improved salt tolerancein a wheat stay-green mutant tasg1. ActaPhysiologiae Plantarum, 2018, 40:39

11. Chen Y.H., Han Y.Y., Zhang M., Zhou S., Kong X.Z.,Wang W.. Overexpression of the Wheat Expansin Gene TaEXPA2 Improved SeedProduction and Drought Tolerance in Transgenic Tobacco Plants. Plos One, 2016,DOI: 10.1371/journal.pone.**

12.Chen Y.H., HanY.Y., Kong X.Z., Kang H.H., Ren Y.Q., Wang W.. Ectopic expression of wheatexpansin gene TaEXPA2 improved the salt tolerance of transgenic tobacco byregulating Na+/K+ and antioxidant competence. Physiologia Plantarum, 2016, DOI: doi:10.1111/ppl.12492

13.Zhao M.R., HanY.Y., Feng Y.N., Li F., Wang W.. Expansins are involved in cell growthmediated by abscisic acidand indole-3-acetic acid under drought stress inwheat. Plant Cell Report, 2012,31(4): 671-685

14. Li A.X., Han Y.Y., Wang X., Chen Y.H., ZhaoM.R., Zhou S.M., Wang W.. Root-specific expression of wheat expansin gene TaEXPB23 enhances root growth anddrought tolerance in tobacco. Environmentaland Experimental Botany, 2014, 110: 73-84

15.Zhou S. HanY.Y., Chen Y.H, Kong X.Z., Wang W.. The involvement of expansins inresponse to water stress during leaf development in wheat. Journal of Plant Physiology, 2015, 183: 64-74

16. Xin Xu, LinWang, Linda Hu, Wilhelm G. Dirks, Yao Zhao, Zhishuai Wei, Dexiang Chen,Zhaoliang Li, Zhanju Wang, Yangyang Han,Liuya Wei, Hans G. Drexler, and Zhenbo Hu. Small Molecular Modulators of JMJD1CPreferentially Inhibit Growth of Leukemia Cells. International Journal ofCancer, 2020, 146(2): 400-412

17. 军，王迪，苗春雷，韩阳阳*；FOXL2 的研究现状及其调控机制，中国细胞